Results 31 to 40 of about 2,719,034 (384)

A numerical model for studying the thermal denaturation-aggregation of whey proteins under continuous thermal processing

International Journal of Food Studies, 2020
A computational fluid dynamics model was designed to study the problem of thermal processing of a liquid food product containing whey proteins within a heat exchanger consisting of heating, holding and cooling tubular sections.
Artemio Plana-Fattori, Christophe Doursat, Alienor Coutouly, Alain Riaublanc, Denis Flick   +4 more
doaj   +1 more source

Driving denaturation: Nanoscale thermal transport as a probe of DNA melting [PDF]

, 2011
DNA denaturation has long been a subject of intense study due to its relationship to DNA transcription and its fundamental importance as a nonlinear, structural transition. Many aspects of this phenomenon, however, remain poorly understood.
Chien, Chih-Chun, Dubi, Yonatan, Velizhanin, Kirill A., Zwolak, Michael   +3 more
core   +2 more sources

Thermal Denaturation of DNA G-Quadruplexes and their Complexes with Ligands: Thermodynamic Analysis of the Multiple States Revealed by Mass Spectrometry

bioRxiv, 2018
As the idea that G-quadruplex nucleic acid structures are involved in cellular processes is gaining support, it becomes important to develop ligands that specifically target G-quadruplexes. However, ligand design is complicated because there are multiple
Adrien Marchand, F. Rosu, R. Zenobi, V. Gabélica   +3 more
semanticscholar   +1 more source

The Effect of Trifluoroethanol and Glycerol on the Thermal Properties of Collagen Using Optical Displacement-Enhanced Heterodyne Polarimeter

Applied Sciences, 2015
An angular displacement-enhanced heterodyne polarimeter has been employed to investigate the interplay between trifluoroethanol (TFE) and glycerol on the thermal denaturation of type I collagen.
Chien-Ming Wu, Horn-Haw Chen, Kai-Han Tseng, Hung-Wei Chen   +3 more
doaj   +1 more source

Determination of Pseudokinase-ligand Interaction by a Fluorescence-based Thermal Shift Assay

Bio-Protocol, 2014
This protocol describes a robust technique for the measurement of pseudokinase-ligand interaction by a fluorescence-based Thermal Shift Assay (TSA).
Isabelle Lucet, Joanne Hildebrand, Peter Czabotar, Jian-Guo Zhang, Nicos Nicola, John Silke, Jeffrey Babon, James Murphy   +7 more
doaj   +1 more source

Renormalisation group determination of the order of the DNA denaturation transition [PDF]

, 2010
We report on the nature of the thermal denaturation transition of homogeneous DNA as determined from a renormalisation group analysis of the Peyrard-Bishop-Dauxois model.
Dietrich S., F. de los Santos, J. M. Romero-Enrique, Jost D., Joyeux M., Jülicher F., Lipowsky R., M. A. Muñoz, Parry A. O., Peyrard M., Romero-Enrique J. M., Romero-Enrique J. M., Romero-Enrique J. M., Schick M., Spohn H.   +14 more
core   +2 more sources

Denaturation studies on bovine serum albumin–bile salt system: Bile salt stabilizes bovine serum albumin through hydrophobicity

Journal of Pharmaceutical Analysis, 2018
Protein denaturation is under intensive research, since it leads to neurological disorders of severe consequences. Avoiding denaturation and stabilizing the proteins in their native state is of great importance, especially when proteins are used as drug ...
Karpagaraj Malarkani, Ivy Sarkar, Susithra Selvam   +2 more
doaj   +1 more source

The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation [PDF]

, 2011
Background: The regulatory subunit (R) of cAMP-dependent protein kinase (PKA) is a modular flexible protein that responds with large conformational changes to the binding of the effector cAMP.
A Horvath, A Natalello, A Zhou, AG Murzin, AM Arutyunyan, AM Fernandez-Escamilla, Angel L. Pey, Angela M. Gronenborn, Anja Underhaug Gjerde, AP Kornev, Aurora Martinez, C Kim, CE Poteet-Smith, CI Bayly, Claudine Mayer, D Hamada, D Vigil, DA Case, DA Leon, DA Leon, DT Haynie, E Deu, EL Greene, F Chiti, G Soldi, H Azakami, H LeVine 3rd, H Rehmann, I Luque, IJ Byeon, IM Plaza del Pino, In-Ja L. Byeon, J Sancho, J Wang, J Wang, J Wu, JA Beavo, JA Carney, JM Canaves, JM Louis, JM Sanchez-Ruiz, JP Ryckaert, JS Richardson, KE Tang, Khanh K. Dao, KK Dao, Knut Teigen, L Holm, M Fandrich, M Fandrich, M Manno, M Mauro, M Thórólfsson, MA Andrade, MS Akhtar, N Ferguson, N Kannan, P Banky, R Aoki, R Das, R Day, R Kopperud, R Shrivastava, RW Carrell, SO Doskeland, SS Taylor, SS Taylor, Stein O. Døskeland, TJ Kamerzell, U Essmann, V Vetri, VJ Hilser, W Wong, WD Cornell, WL Jorgensen, WN Lanzilotta, Y Su   +76 more
core   +11 more sources

Structural changes in cartilage and collagen studied by high temperature Raman spectroscopy [PDF]

, 2017
Understanding the high temperature behavior of collagen and collagenous tissue is important for surgical procedures and biomaterials processing for the food, pharmaceutical, and cosmetics industries. One primary event for proteins is thermal denaturation
Dudhia, J, Fields, M, McMillan, P F, Spencer, N   +3 more
core   +2 more sources

Direct observation of large temperature fluctuations during DNA thermal denaturation [PDF]

, 2006
In this paper we report direct measurement of large low frequency temperature fluctuations in double stranded (ds) DNA when it undergoes thermal denaturation transition.
Chatterji, Dipankar, Nagapriya, K. S., Raychaudhuri, A. K.   +2 more
core   +2 more sources