Results 181 to 190 of about 6,447 (219)

Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes. [PDF]

Proteome Sci, 2016
Mateus A, Määttä TA, Savitski MM.
europepmc   +1 more source

Sesamin Ameliorates High‐Sugar, High‐Fat Diet‐Induced Hepatic Dysfunction via CYP1A2‐Mediated Regulation of Lipid Metabolism and Oxidative Stress

Journal of Cellular and Molecular Medicine, Volume 30, Issue 14, July 2026.
ABSTRACT BackgroundHigh‐sugar, high‐fat diets (HSDFD) can lead to hepatic dysfunction, but the molecular mechanisms underlying protective compounds like sesamin remain unclear MethodsWe employed a multi‐faceted approach combining in silico and in vivo techniques.
Xiliang Zhu, Jie Yan, Qi Liu, Zhaoyun Cheng, Yi Luo   +4 more
wiley   +1 more source

Photobiomodulation restores blood–brain barrier integrity after hypoxia via endothelial von Willebrand factor modulation in a humanised tricellular transwell model

The Journal of Physiology, Volume 604, Issue 14, Page 6080-6103, 15 July 2026.
Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos, Denis E. Bragin, Nagesh C. Shanbhag, Luise Schlotterose, Mootaz M. Salman   +4 more
wiley   +1 more source

Comprehensive Chemoproteomics Unveils Selective HMG-CoA Synthase 1 Inhibitors for Targeting Mevalonate Metabolism in Cancer. [PDF]

J Am Chem Soc
Sun L, Yi SA, Pham BQ, Mocellin A, Sen S, de la Cruz MJ, Ordureau A, An H.   +7 more
europepmc   +1 more source

Label-Free Target Discovery Strategy for Natural Active Products. [PDF]

Biomolecules
Shan L, Chen Y, Cao X, Jin X, Liu B.
europepmc   +1 more source

Biophysical Sensing Tools in Drug Discovery: Integrating Kinetics, Thermodynamics, Cellular Target Engagement and Structure. [PDF]

Sensors (Basel)
Balıkçı E, Akıl C.
europepmc   +1 more source

3D Proteomics: Structural, Functional, Chemical and Biomarker Discovery Proteomics With LiP-MS. [PDF]

Mol Cell Proteomics
Elsässer F, de Souza N, Picotti P.
europepmc   +1 more source

Dissection of Genotype-Dependent Responses Reveals Leaf Proteome Signatures Associated with Maize Thermotolerance During Flowering Under Enclosure-Imposed Heat Stress. [PDF]

Proteomes
Liu R, Li X, Zha Z, Zhang M, Kong L, Cui Y, Zhao W, Meng Q, Wang Y, Chen Y.   +9 more
europepmc   +1 more source

Proteome-Wide Monitoring of Drug Action in Living Cells Using a Novel Label-Free Solvent-Based Shift Assay. [PDF]

Mol Cell Proteomics
Steinbrunn D, Cepeleaga C, Betz A, Kibar G, Holzner M, Maier SK, Zasada C, Hagemann G, Sieber SA, Hahne H.   +9 more
europepmc   +1 more source

Expanding the Reach of Membrane Protein-Ligand Interaction Studies Through the Integration of Mass Spectrometry and Membrane Mimetics. [PDF]

Proteomics
Lambos JC, Bhattacharya A, Al-Seragi M, Duong van Hoa F.   +3 more
europepmc   +1 more source