Results 41 to 50 of about 10,764 (259)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Synthesis and characterization of N-octanoyl glycol chitosan as a novel temperature and pH-sensitive injectable hydrogel for biomedical applications

Materials & Design
Multi-responsive hydrogel formulations have received significant attention in biomedical applications as promising injectable depots and platforms for tissue regeneration.
Hoang-Minh Pham, Chanyang Joo, Mst Jannatul Ferdous, Israr Ali, Sun-Woong Kang, Kang Moo Huh   +5 more
doaj   +1 more source

Comparative evaluation of RetCam vs. gonioscopy images in congenital glaucoma

Indian Journal of Ophthalmology, 2014
Purpose: To compare clarity, exposure and quality of anterior chamber angle visualization in congenital glaucoma patients, using RetCam and indirect gonioscopy images. Design: Cross-sectional study Participants. Congenital glaucoma patients over age of 5
Raj V Azad, Parijat Chandra, Anuradha Chandra, Aparna Gupta, Viney Gupta, Ramanjit Sihota   +5 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Brachytherapy of intra ocular tumors using ′BARC I-125 Ocu-Prosta seeds′: An Indian experience

Indian Journal of Ophthalmology, 2014
Aim: To report our experience of brachytherapy using ′BARC I-125 Ocu-Prosta seeds′ for the management of intraocular tumors with regard to tumor control, globe preservation visual outcome, and patient survival at Sankara Nethralaya, Chennai, India ...
Vikas Khetan, Lingam Gopal, Mahesh P Shanmugam, Aditi Gupta, Tarun Sharma, Pramod Bhende, Siva Muthukumar, R Subramaniam, Thayalan Kuppuswamy, S K Saxena, Ashutosh Dash   +10 more
doaj   +1 more source

Colloidal Gels: Equilibrium and Non-Equilibrium Routes [PDF]

, 1995
We attempt a classification of different colloidal gels based on colloid-colloid interactions. We discriminate primarily between non-equilibrium and equilibrium routes to gelation, the former case being slaved to thermodynamic phase separation while the ...
A Duquennoy, A Dutrey, AC Raga, AM Ghez, B Reipurth, B Reipurth, B Reipurth, B Reipurth, C Leinert, EJ Wampler, F Malbet, G Basri, I Joncour, J Solf, J-M Mariotti, LB Lucy, R Gredel, R Mathieu   +17 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

The effect of multimedia interventions on the informed consent process for cataract surgery in rural South India

Indian Journal of Ophthalmology, 2014
Context: The provision of ocular surgical interventions for poorer, less educated populations is increasing as a result of increased globalization and outreach.
Abraar Karan, Prashanth Somasundaram, Haben Michael, Aryan Shayegani, Hylton Mayer   +4 more
doaj   +1 more source

Viscoelastic gels of guar and xanthan gum mixtures provide long-term stabilization of iron micro- and nanoparticles [PDF]

, 2012
Iron micro- and nanoparticles used for groundwater remediation and medical applications are prone to fast aggregation and sedimentation. Diluted single biopolymer water solutions of guar gum (GG) or xanthan gum (XG) can stabilize these particles for few ...
A Molfetta Di, A Tiraferri, AB Rodd, C Noubactep, D Kim, D Risica, Dingqi Xue, DL Huber, E Choppe, E Dalla Vecchia, E Dalla Vecchia, F García-Ochoa, FS Freyria, G Schramm, ICM Dea, ICM Dea, IT Norton, J Amundarain, JA Casas, K Hyun, KJ Cantrell, L Zhong, M Iijima, M Milas, M Oostrom, MJ Truex, ML Williams, PHT Uhlherr, PJ Flory, Rajandrea Sethi, RHW Wientjes, S Comba, S Comba, T Phenrat, TG Mezger, V Zolla, VB Pai, W Zhang, X Li, Y Qiang, Z Xiu   +40 more
core   +1 more source

Advancing Research on Biomaterials and Biological Materials with Scanning Electron Microscopy under Environmental and Low Vacuum Conditions

Advanced Engineering Materials, EarlyView.
Herein, environmental scanning electron microscopy (ESEM) is discussed as a powerful extension of conventional SEM for life sciences. By combining high‐resolution imaging with variable pressure and humidity, ESEM allows the analysis of untreated biological materials, supports in situ monitoring of hydration‐driven changes, and advances the functional ...
Jendrian Riedel, Lea Dierker, Antoine Eyram Kwame, Kim Nora Wagner, Jonas J. Unterholzner, Jan‐Henning Dirks, Dorothea Brüggemann   +6 more
wiley   +1 more source