ELOVL3 regulates phospholipid homeostasis and thermogenesis in brown adipose tissue [PDF]
Journal of Lipid ResearchNonshivering thermogenesis plays an important role in maintaining body temperature and energy homeostasis. Elongation of very long-chain fatty acid protein 3 (ELOVL3), which catalyzes the synthesis of C20-C24 fatty acids, is induced in brown adipose ...
Zhenbang Qin +7 more
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The impact of dietary factors on the function of brown and beige adipose tissues—implications on health and disease [PDF]
Frontiers in NutritionThe development of strategies that promote the activation of adaptive thermogenesis in brown and beige adipose tissues is expected to lead to advances in the prevention and treatment of obesity, diabetes, and cardiovascular diseases.
Bruna Bombassaro +7 more
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Loss of histone methyltransferase Smyd3 triggers WAT browning and adaptive thermogenesis via enhancing PPARγ expression in a H4K20me3-dependent manner [PDF]
Journal of Translational MedicineAdaptive thermogenesis driven by brown/beige adipose tissue has gained attention as a promising strategy for combating obesity. Histone methyltransferase SET and MYND Domain Containing 3 (Smyd3) is strongly associated with metabolic and cardiovascular ...
Meiling Shu +7 more
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Brown adipose tissue and skeletal muscle coordinately contribute to thermogenesis in mice [PDF]
eLifeEndotherms increase the rate of metabolism in metabolic organs as one strategy to cope with a decline in the temperature of the external environment. However, an additional major contributor to maintenance of body temperature in a cold environment is ...
Yuna Izumi-Mishima +11 more
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Akebia Saponin D Targeting Ubiquitin Carboxyl‐Terminal Hydrolase 4 Promotes Peroxisome Proliferator‐Activated Receptor Gamma Deubiquitination and Activation of Brown Adipose Tissue Thermogenesis in Obesity [PDF]
MedCommPromoting thermogenesis in adipose tissue to enhance energy expenditure is widely regarded as a promising strategy for obesity treatment. However, the development of effective thermogenic drugs remains challenging.
Lang Chen +13 more
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Emerging roles of histone deacetylases in adaptive thermogenesis
Frontiers in Endocrinology, 2023 Brown and beige adipose tissues regulate body energy expenditure through adaptive thermogenesis, which converts energy into heat by oxidative phosphorylation uncoupling.
Ruonan Zhou +8 more
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Frontiers in Plant Science, 2022 Floral thermogenesis is coupled with odor emission in known thermogenic plants. It is widely accepted that elevation in floral temperature can help release of volatile organic compounds (VOCs).
Ruohan Wang +12 more
doaj +1 more source
Adipocyte, 2023 Brown adipocytes were proposed to reverse metabolic conditions such as obesity and diabetes, which make them potential for therapeutic applications.
Van Thi-Tuong Nguyen +2 more
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Molecular Metabolism, 2020 Objective: Brown adipose tissue (BAT)–mediated thermogenesis plays a key role in energy homeostasis and the maintenance of body temperature. Previous work suggests that brain-derived neurotrophic factor (BDNF) is involved in BAT thermogenesis, but the ...
He You, Pengcheng Chu, Wei Guo, Bai Lu
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Lipokines and Thermogenesis [PDF]
Endocrinology, 2019 Abstract Adaptive thermogenesis is a catabolic process that consumes energy-storing molecules and expends that energy as heat in response to environmental changes. This process occurs primarily in brown and beige adipose tissue. Thermogenesis is regulated by many factors, including lipid derived paracrine and endocrine hormones called ...
Matthew D Lynes +2 more
openaire +2 more sources