Results 1 to 10 of about 62,258 (326)
Lipokines and Thermogenesis [PDF]
Endocrinology, 2019 Abstract Adaptive thermogenesis is a catabolic process that consumes energy-storing molecules and expends that energy as heat in response to environmental changes. This process occurs primarily in brown and beige adipose tissue. Thermogenesis is regulated by many factors, including lipid derived paracrine and endocrine hormones called ...
Matthew D Lynes +2 more
openaire +3 more sources
Developmental Cell, 2017 THADA has been associated with cold adaptation and diabetes in humans, but the cellular and molecular basis of its function has been unknown. Moraru and colleagues (2017) report in this issue of Developmental Cell that it triggers thermogenesis by uncoupling ATP hydrolysis from calcium transport into the endoplasmic reticulum.
Nirmalya Chatterjee +2 more
openaire +4 more sources
Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue [PDF]
, 2007 In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis).
Bianco, Antonio C. +12 more
core +1 more source
Bioscience Reports, 2001 The article discusses the importance of avian skeletal muscle as a source for heat generation by means of both shivering and non-shivering. Non-shivering thermogenesis in birds is still a polemic issue. Recent evidence at the molecular/cellular level indicates, however, that this type of heat generation may also exist among birds.
Claudia R. Vianna +2 more
openaire +3 more sources
Thermogenesis in ectothermic vertebrates [PDF]
Temperature, 2015 Thermogenesis refers to the production of heat by living organisms as a by-product of metabolic activity and is the principal thermoregulatory effector employed by endothermic organisms.
Andrade, Denis Vieira +2 more
openaire +5 more sources
Thyroid thermogenesis in adult rat hepatocytes in primary monolayer culture: direct action of thyroid hormone in vitro. [PDF]
, 1979 We have studied the effect of 3,5,3'-triiodothyronine (T3) on the respiration of adult rat hepatocytes in primary monolayer culture prepared from hypothyroid rat liver. After addition of T3 to the culture medium at a concentration of 2 x 10(-7) M, oxygen
Bissell, DM +2 more
core +2 more sources
Glucagon, GLP-1 and Thermogenesis [PDF]
International Journal of Molecular Sciences, 2019 Brown adipose tissue (BAT) thermogenesis is a conserved mechanism to maintain body temperature in mammals. However, since BAT contribution to energy expenditure can represent a relevant modulator of metabolic homeostasis, many studies have focused on the nervous system and endocrine factors that control the activity of this tissue.
Ismael González-García +4 more
openaire +7 more sources
Wireless optogenetics protects against obesity via stimulation of non-canonical fat thermogenesis. [PDF]
, 2020 Cold stimuli and the subsequent activation of β-adrenergic receptor (β-AR) potently stimulate adipose tissue thermogenesis and increase whole-body energy expenditure.
Ferro, Marc D +8 more
core
Adipocyte Liver Kinase b1 Suppresses Beige Adipocyte Renaissance Through Class IIa Histone Deacetylase 4. [PDF]
, 2017 Uncoupling protein 1+ beige adipocytes are dynamically regulated by environment in rodents and humans; cold induces formation of beige adipocytes, whereas warm temperature and nutrient excess lead to their disappearance. Beige adipocytes can form through
Chawla, Ajay +6 more
core +1 more source
mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]
, 2016 Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Albert V +12 more
core +4 more sources