Results 201 to 210 of about 37,151 (264)

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, Volume 293, Issue 16, Page 4789-4804, August 2026.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source

Immune checkpoint blockade targets macrophage PD-1 to exacerbate metabolic dysfunction. [PDF]

Immunometabolism (Cobham)
Song Z, Frezza C.
europepmc   +1 more source

Fast & fuelious: the malate–aspartate shuttle in brown adipocyte lipid metabolism

The FEBS Journal, Volume 293, Issue 15, Page 4480-4483, August 2026.
Brown adipose tissue (BAT) produces heat in response to cold exposure, for which it relies on the coordination of aerobic and anaerobic metabolism. However, how reaction intermediates connect these two essential pathways is unclear. In this issue of The FEBS Journal, Veliova et al., report that the malate–aspartate shuttle (MAS) supports norepinephrine‐
Lukas Blaas, Alexander Bartelt
wiley   +1 more source

Bioactive Constituents and Therapeutic Mechanisms of Shenfu Decoction in a Rat Model of Seawater-Immersion-Induced Accidental Hypothermia. [PDF]

Pharmaceuticals (Basel)
Gong Y, Wang Z, Ben Y, Chen H, Wang Y, Sun C, Deng H, Zhang H, Yin Z, Gu W.   +9 more
europepmc   +1 more source

A nutrient-hormone axis pivots an energy trade-off between resting thermogenesis and movement expenditure. [PDF]

J Sport Health Sci
Rusu PM, Htin Aung O, Chan AY, Wu Y, Cleofe MAS, Trewin AJ, Giri S, Foollee A, Flores SA, Lemus MB, Greaves E, Hille S, Dodd GT, McGrath MJ, Müller OJ, Stefanidis A, Rose AJ.   +16 more
europepmc   +1 more source

Phosphomannomutase 1 restrains adipose thermogenic programming via inosine signaling. [PDF]

Mol Metab
Ye Y, Xu R, Liu T, Su Y, Lu X, Sun J, Zhao J, Lu Y, Yang Y, Han J.   +9 more
europepmc   +1 more source

Diet-Induced Browning of White Adipose Tissue: Molecular Targets, Mechanisms, and Therapeutic Potential. [PDF]

Curr Issues Mol Biol
Yang ZD, Chen JW, Mei YX, Xia XW, Gong YJ, Ding WJ.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Nonshivering thermogenesis

Brain Research Bulletin, 1984
Nonshivering thermogenesis was originally defined as a cold-induced increase in heat production not associated with the muscle activity of shivering. Recent research shows it to be a metabolic process located primarily in brown adipose tissue and controlled by the activity of the sympathetic nervous supply of this tissue.
Jean Himms-Hagen, J Himms-Hagen
exaly   +3 more sources

Thermogenesis and Obesity

British Medical Bulletin, 1981
Obesity is generally considered to be the major nutritional disorder in the Western world, affecting, for example, some 10% of the middle-aged population in the UK, with up to 50% of the same group being overweight and at an increased risk of disease and early death.
W P, James, P, Trayhurn
openaire   +2 more sources

Perinatal thermogenesis

Early Human Development, 1995
The rapid initiation of thermogenesis is crucial for the survival of newborn infants. At birth the fetus must adapt to cooling, increased oxygenation and separation from the placenta. An experimental approach in the chronically instrumental fetal sheep of 'simulated birth in utero' allowed the evaluation of each of these stimuli sequentially.
T R, Gunn, P D, Gluckman
openaire   +2 more sources