Results 141 to 150 of about 37,070 (254)

Calcium Beta‐Hydroxy‐Beta‐Methylbutyrate‐Enriched Nutritional Supplementation During Dietary Weight Loss in Adults With Obesity: A Randomized Controlled Trial

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Dietary and pharmacologic weight loss can reduce skeletal muscle. Whether calcium beta‐hydroxy‐beta‐methylbutyrate (CaHMB)‐enriched supplementation preserves muscle while promoting fat loss in adults with obesity remains uncertain. We evaluated a CaHMB‐enriched nutritional supplement during energy restriction.
Jiaojiao Jiang   +5 more
wiley   +1 more source

Prolactin and Triiodothyronine Modulate Seasonal Variation in Brown Adipose Tissue in Djungarian Hamsters

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 7, Page 710-718, August 2026.
ABSTRACT Seasonal photoperiodic cycles regulate energy rheostasis in many animals. Brown adipose tissue (BAT) and the liver are key metabolic organs that show remarkable plasticity in response to photoperiodic conditions. Prolactin (PRL) and thyroid hormones are endocrine signals that transmit neural‐derived photoperiodic time measurement encoding to ...
Sayantan Sur   +5 more
wiley   +1 more source

Deep Learning‐Driven Computational Imaging for Noninvasive Monitoring System of Brain Temperature and Metabolism: A Hypothermia Validation for Acute Ischemic Stroke

open access: yesMedComm, Volume 7, Issue 8, August 2026.
This study presents the first proof‐of‐concept framework for 3D brain temperature and metabolism imaging using deep learning and clinical validation. An integrated multimodal instrument enables noninvasive neuro‐monitoring, while MRI‐based 3D modeling and computational imaging improve prediction accuracy, visualization quality, and spatial resolution ...
Tianhang Yang   +12 more
wiley   +1 more source

Improving incretin-mediated body weight loss via energy expenditure. [PDF]

open access: yesTrends Endocrinol Metab
Elmendorf AJ   +3 more
europepmc   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang   +9 more
wiley   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang   +6 more
wiley   +1 more source

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