Results 21 to 30 of about 69,336 (236)

At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1

Molecular Metabolism, 2019
Objective: Hyperthyroidism is associated with increased metabolism (“thyroid thermogenesis”) and elevated body temperature, often referred to as hyperthermia.
Claudia Dittner, Erik Lindsund, Barbara Cannon, Jan Nedergaard   +3 more
doaj   +1 more source

Aqueous extracts of Aconite promote thermogenesis in rats with hypothermia via regulating gut microbiota and bile acid metabolism

Chinese Medicine, 2021
Background Intermittent or prolonged exposure to severe cold stress disturbs energy homeostasis and can lead to hypothermia, heart failure, Alzheimer’s disease, and so on. As the typical “hot” traditional Chinese medicine, Aconite has been widely used to
Juan Liu, Yuzhu Tan, Hui Ao, Wuwen Feng, Cheng Peng   +4 more
doaj   +1 more source

Involvement of TRP Channels in Adipocyte Thermogenesis: An Update

Frontiers in Cell and Developmental Biology, 2021
Obesity prevalence became a severe global health problem and it is caused by an imbalance between energy intake and expenditure. Brown adipose tissue (BAT) is a major site of mammalian non-shivering thermogenesis or energy dissipation.
Wuping Sun, Yixuan Luo, Fei Zhang, Shuo Tang, Tao Zhu   +4 more
doaj   +1 more source

Thermal stress induces glycolytic beige fat formation via a myogenic state. [PDF]

, 2019
Environmental cues profoundly affect cellular plasticity in multicellular organisms. For instance, exercise promotes a glycolytic-to-oxidative fibre-type switch in skeletal muscle, and cold acclimation induces beige adipocyte biogenesis in adipose tissue.
A Jaworski, AA Lans van der, Andrew Brack, Annarita Scaramozza, C Trapnell, Carlos Henrique Sponton, DC Berry, ES Bachman, H Ohno, J Nedergaard, J Sanchez-Gurmaches, J Wu, JR Arch, JZ Long, K Ikeda, K Nishijo, K Shinoda, Kazuki Tajima, Kenji Ikeda, Kosaku Shinoda, Kyeongkyu Kim, L Kazak, L Vishvanath, L Ye, LZ Sharp, M Razzoli, ME Lidell, MJ Hanssen, ML Gantner, MS Rodeheffer, P Cohen, P Seale, Qiang Wang, S Collins, S Heinz, S Jung, S Kajimura, S Tripathi, Shingo Kajimura, T Buch, T Yoneshiro, Takeshi Yoneshiro, VK Mootha, Y Hasegawa, YH Lee, YH Tseng, Yong Chen, Zachary Brown, ZF Yang   +48 more
core   +2 more sources

Gsα deficiency in the dorsomedial hypothalamus leads to obesity, hyperphagia, and reduced thermogenesis associated with impaired leptin signaling

Molecular Metabolism, 2019
Objective: Gsα couples multiple receptors, including the melanocortin 4 receptor (MC4R), to intracellular cAMP generation. Germline inactivating Gsα mutations lead to obesity in humans and mice.
Min Chen, Eric A. Wilson, Zhenzhong Cui, Hui Sun, Yogendra B. Shrestha, Brandon Podyma, Christina H. Le, Benedetta Naglieri, Karel Pacak, Oksana Gavrilova, Lee S. Weinstein   +10 more
doaj   +1 more source

Chewing increases postprandial diet-induced thermogenesis

Scientific Reports, 2021
Slow eating, which involves chewing food slowly and thoroughly, is an effective strategy for controlling appetite in order to avoid being overweight or obese.
Yuka Hamada, Naoyuki Hayashi
doaj   +1 more source

Thyroid thermogenesis in adult rat hepatocytes in primary monolayer culture: direct action of thyroid hormone in vitro. [PDF]

, 1979
We have studied the effect of 3,5,3'-triiodothyronine (T3) on the respiration of adult rat hepatocytes in primary monolayer culture prepared from hypothyroid rat liver. After addition of T3 to the culture medium at a concentration of 2 x 10(-7) M, oxygen
Bissell, DM, Edelman, IS, Ismail-Beigi, F   +2 more
core   +2 more sources

mTORC1 inhibition uncouples lipolysis and thermogenesis in white adipose tissue to contribute to alcoholic liver disease

Hepatology Communications, 2023
Background:. Adipose tissue thermogenic activities use fatty acids from lipolysis for heat generation. Therefore, a tight coupling between lipolysis and thermogenesis is physiologically imperative in maintaining not only body temperature but also lipids ...
Qing Song, Yingli Chen, Qinchao Ding, Alexandra Griffiths, Lifeng Liu, Jooman Park, Chong Wee Liew, Natalia Nieto, Songtao Li, Xiaobing Dou, Yuwei Jiang, Zhenyuan Song   +11 more
doaj   +1 more source

Autonomic regulation of brown adipose tissue thermogenesis in health & disease: Potential clinical applications for altering BAT thermogenesis

Frontiers in Neuroscience, 2014
From mouse to man, brown adipose tissue (BAT) is a significant source of thermogenesis contributing to the maintenance of the body temperature homeostasis during the challenge of low environmental temperature.
Domenico eTupone, Christopher J. Madden, Shaun F. Morrison   +2 more
doaj   +1 more source

Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice [PDF]

, 2012
Insulin resistance and impaired glucose homoeostasis are important indicators of Type 2 diabetes and are early risk factors of AD (Alzheimer's disease).
Alex J. Harper, Alison D. McNeilly, Almind, Arch, Azzu, Balleza-Tapia, Biessels, Burcelin, Butler, Cai, Cannon, Choi, Cioffi, Cole, Craft, Craft, D. Lee Hamilton, David R. Howlett, De Felice, de la Monte, de la Monte, Dominguez, Folch, Fromme, Frölich, Fukumoto, Harrison, Hassing, Ho, Huse, Ishrut Hussain, Janson, Jennifer Gallagher, John R. Speakman, Judy Latcham, Kirsten A. Bannon, Kobayashi, Kontani, Kus, LaFerla, Laura A. Burgess, Lee, Li, Lobke M. Vaanholt, Luchsinger, Luo, Mensink, Michael L.J. Ashford, Mirshamsi, Paul J. Meakin, Pietrak, Rapoport, Rivera, Roberds, Sankaranarayanan, Selman, Speakman, Steen, Tiraby, Vassar, Vassar, Vattemi, Xie   +62 more
core   +4 more sources