Results 61 to 70 of about 65,191 (322)

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

The Role of the Sympathetic Nervous System in the Hypothermic Effect of d-Fenfluramine [PDF]

, 2002
Experiments in this dissertation were conducted to characterize the effects of d-fenfluramine on body temperature and the mechanisms by which d-fenfluramine alter body temperature.
Subramanian, Srividya
core   +1 more source

Consistency of metabolic responses and appetite sensations under postabsorptive and postprandial conditions [PDF]

, 2012
The present study aimed to investigate the reliability of metabolic and subjective appetite responses under fasted conditions and following consumption of a cereal-based breakfast. Twelve healthy, physically active males completed two postabsorption (PA)
Astbury, Atkinson, Atkinson, Bland, Blundell, Compher, Craig, De Castro, Emma J. Stevenson, Flint, Gibson, Hopkins, Isaksson, Javier T. Gonzalez, Katch, Levine, Miles, Penny L.S. Rumbold, Peracchi, Peronnet, Piers, Ping-Delfos, Raben, Rachel C. Veasey, Rosen, Segal, Stevenson, Stubbs, Stunkard, Weststrate   +29 more
core   +3 more sources

Biomimetic and Compressible Wood Phase Change Gel With Hierarchically Aligned Lamellar Structure for Controlled Thermal Management

Carbon Energy, EarlyView.
Inspired by skeletal muscle thermogenesis, a wood phase change gel exhibiting mechano‐controlled heat release is developed. Under compression, the wood phase change gel overcomes its energy barrier, inducing its phase change from supercooling to crystallization and raising its overall temperature by around 5°C.
Jiazuo Zhou, Yifan Liu, Xinbei Jia, Yudong Li, Xiaohan Sun, Xinyao Ji, Yuan Yu, Taikun Yao, Zhuoer Li, Jian Li, Haiyue Yang, Yao Xiao, Wentao Gan, Chengyu Wang   +13 more
wiley   +1 more source

Nutritional Influences on Brown and Beige Adipocyte: Unraveling the Molecular Mechanisms and Metabolic Implications. [PDF]

Food Sci Nutr
Nutrient‐focused dietary strategies can enhance BAT function and activity, thereby contributing to the modulation of metabolic disorders and the optimization of metabolic health. ABSTRACT Brown adipose tissue (BAT) and beige adipose tissue (beige fat) function as thermogenic organs, significantly influencing human metabolism through various mechanisms.
Wang Y, Zhang K, Kan C, Zhang W, Sun X, Li L.   +5 more
europepmc   +2 more sources

Central control of brown adipose tissue thermogenesis

Frontiers in Endocrinology, 2012
Thermogenesis, the production of heat energy, is an essential component of the homeostatic repertoire to maintain body temperature during the challenge of low environmental temperature and plays a key role in elevating body temperature during the febrile
Shaun F. Morrison, Christopher J. Madden, Domenico eTupone   +2 more
doaj   +1 more source

A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis

Nature Communications, 2022
The signaling mechanisms regulating adipose thermogenesis have not been fully elucidated. Here, the authors show that a brown fat-enriched adipokine ADISSP promotes adipose thermogenesis and improves metabolic health independently of b-adrenergic ...
Qingbo Chen, Lei Huang, Dongning Pan, Kai Hu, Rui Li, Randall H. Friedline, Jason K. Kim, Lihua Julie Zhu, David A. Guertin, Yong-Xu Wang   +9 more
doaj   +1 more source

THADA regulates the organismal balance between energy storage and heat production [PDF]

, 2017
Human susceptibility to obesity is mainly genetic, yet the underlying evolutionary drivers causing variation from person to person are not clear. One theory rationalizes that populations that have adapted to warmer climates have reduced their metabolic ...
Braeckman, Bart, Cakan-Akdogan, Gulcin, Frejno, Martin, Jabs, Markus, Males, Matilda, Moraru, Alexandra, Muelleder, Michael, Mueller, Sandra, Ralser, Markus, Strassburger, Katrin, Teleman, Aurelio A   +10 more
core   +2 more sources

Adaptive thermogenesis in humans [PDF]

International Journal of Obesity, 2010
The increasing prevalence of obesity and its comorbidities reflects the interaction of genes that favor the storage of excess energy as fat with an environment that provides ad libitum availability of energy-dense foods and encourages an increasingly sedentary lifestyle.
Rudolph L. Leibel, Michael Rosenbaum
openaire   +3 more sources

Heart failure and obesity: Translational approaches and therapeutic perspectives. A scientific statement of the Heart Failure Association of the ESC

European Journal of Heart Failure, EarlyView.
Abstract Obesity and heart failure (HF) represent two growing pandemics. In the general population, obesity affects one in eight adults and is linked with an increased risk for HF. Obesity is even more common in patients with HF, where it complicates the diagnosis of HF and is linked with worse symptoms and impaired exercise capacity. Over the past few
Gianluigi Savarese, Gabriele G. Schiattarella, Felix Lindberg, Markus S. Anker, Antoni Bayes‐Genis, Magnus Bäck, Frieder Braunschweig, Chiara Bucciarelli‐Ducci, Javed Butler, Antonio Cannata, Federico Capone, Ovidiu Chioncel, Emilia D'Elia, Arantxa González, Gerasimos Filippatos, Nicolas Girerd, Jean‐Sébastien Hulot, Carolyn S.P. Lam, Lars H. Lund, Christoph Maack, Brenda Moura, Mark C. Petrie, Massimo Piepoli, Abdullah Shehab, Mehmet B. Yilmaz, Peter Seferovic, Carlo G. Tocchetti, Giuseppe M.C. Rosano, Marco Metra   +28 more
wiley   +1 more source