Results 61 to 70 of about 83,845 (311)
Nature Medicine, 2017 Uncoupling protein 1 (UCP1) plays a central role in nonshivering thermogenesis in brown fat; however, its role in beige fat remains unclear. Here we report a robust UCP1-independent thermogenic mechanism in beige fat that involves enhanced ATP-dependent ...
K. Ikeda +13 more
semanticscholar +1 more source
Energy expenditure during overfeeding
Nutrition & Metabolism, 2006 The large inter-individual variation in weight gain during standardized overfeeding together with a weight gain that is often less than theoretically calculated from the energy excess suggest that there are differences between persons in the capacity to ...
Westerterp Klaas R, Joosen Annemiek MCP
doaj +1 more source
Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis
Scientific Reports, 2022 Brown adipose tissue (BAT) dissipates chemical energy as heat through uncoupling protein 1 (UCP1). The induction of mitochondrial reactive oxygen species (ROS) in BAT was recently identified as a mechanism that supports UCP1-dependent thermogenesis.
Sayaka Saijo +8 more
doaj +1 more source
Violet-light suppression of thermogenesis by Opsin 5 hypothalamic neurons
Nature, 2020 The opsin family of G-protein-coupled receptors are used as light detectors in animals. Opsin 5 (also known as neuropsin or OPN5) is a highly conserved opsin that is sensitive to visible violet light 1 , 2 .
Kevin X. Zhang +20 more
semanticscholar +1 more source
Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges
Advanced Functional Materials, EarlyView.Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley +1 more source
Huddling behavior regulate adaptive thermogenesis in Brandt’s voles (Lasiopodomys brandtii)
Cell & BioscienceBackground Brown adipose tissue (BAT) is the main site of non-shivering thermogenesis (NST) in small mammals, playing an important role in maintaining body temperature and energy balance. Huddling is a behavioral strategy for small rodents to save energy
Min Liu +3 more
doaj +1 more source
Bioactivity in Whey Proteins Influencing Energy Balance [PDF]
, 2012 Peer-reviewedObesity develops due to energy (food) intake exceeding energy expenditure. Nutrients that reduce the positive energy balance are thus being considered as therapies to combat obesity.
Cotter, Paul D. +4 more
core +1 more source
IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis.
Journal of Clinical Investigation, 2021 Adipose thermogenesis is repressed in obesity, reducing the homeostatic capacity to compensate for chronic overnutrition. Inflammation inhibits adipose thermogenesis, but little is known about how this occurs.
Shuai Yan +8 more
semanticscholar +1 more source
Advanced Science, EarlyView.Mid‐infrared optoacoustic microscopy (MiROM) acquires lipid‐ and protein‐ associated vibrational contrast in intact fat tissue without dyes, preserving native tissue architecture. Through lateral and axial segmentation, MiROM tracks intrinsic intracellular changes during postnatal remodeling. A quantitative spatial analysis tool (Q‐SAT) maps white‐ and
Myeongseop Kim +7 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai +6 more
wiley +1 more source