Results 71 to 80 of about 83,845 (311)

Creatine and low-dose lithium supplementation separately alter energy expenditure, body mass, and adipose metabolism for the promotion of thermogenesis

iScience
Summary: Nutraceutical approaches to promote adipose tissue thermogenesis may help to prevent obesity onset. Creatine is a critical regulator of adipose metabolic function and low-dose lithium supplementation has been shown to promote adipose ...
M.S. Finch, G.L. Gardner, J.L. Braun, M.S. Geromella, J. Murphy, K. Colonna, R. Dhaliwal, A. Retta, A. Mohammad, J.A. Stuart, P.J. LeBlanc, V.A. Fajardo, B.D. Roy, R.E.K. MacPherson   +13 more
doaj   +1 more source

Panax notoginseng saponins modulate the gut microbiota to promote thermogenesis and beige adipocyte reconstruction via leptin-mediated AMPKα/STAT3 signaling in diet-induced obesity

Theranostics, 2020
Background: Activation of the thermogenic program in white and brown adipocytes presents a promising avenue for increasing energy expenditure during the treatment of obesity.
Yu Xu, Ning Wang, H. Tan, Sha Li, Cheng Zhang, Zhangjin Zhang, Yibin Feng   +6 more
semanticscholar   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that preces the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Mitochondrial H+ Leak and Thermogenesis.

Annual Review of Physiology, 2021
Mitochondria of all tissues convert various metabolic substrates into two forms of energy: ATP and heat. Historically, the primary focus of research in mitochondrial bioenergetics was on the mechanisms of ATP production, while mitochondrial thermogenesis
A. Bertholet, Yuriy Kirichok
semanticscholar   +1 more source

Octopamine drives honeybee thermogenesis

eLife, 2022
In times of environmental change species have two options to survive: they either relocate to a new habitat or they adapt to the altered environment. Adaptation requires physiological plasticity and provides a selection benefit.
Sinan Kaya-Zeeb, Lorenz Engelmayer, Mara Straßburger, Jasmin Bayer, Heike Bähre, Roland Seifert, Oliver Scherf-Clavel, Markus Thamm   +7 more
openaire   +4 more sources

A Functionally Conserved Enhancer is Critical for PGC1A Expression and Thermogenesis in Brown Fat

Advanced Science, EarlyView.
An evolutionarily conserved enhancer controls PGC1A expression and thermogenic activation in brown adipose tissue. Integrative multi‐omics analyses identify two BAT‐specific enhancers, with PGC1A‐En1 functioning as the dominant regulatory element that maintains thermogenic capacity across species.
Duo Su, Haosen Yang, Xiaokai Li, Tingting Jiang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Li Li, Hongping Zhang, Linjie Wang   +10 more
wiley   +1 more source

Latest advances in the regulatory genes of adipocyte thermogenesis

Frontiers in Endocrinology, 2023
An energy imbalance cause obesity: more energy intake or less energy expenditure, or both. Obesity could be the origin of many metabolic disorders, such as type 2 diabetes and cardiovascular disease.
Tao Nie, Jinli Lu, Hua Zhang, Liufeng Mao   +3 more
doaj   +1 more source

Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue.

Cell Reports, 2019
The relation between gut microbiota and the host has been suggested to benefit metabolic homeostasis. Brown adipose tissue (BAT) and beige adipocytes facilitate thermogenesis to maintain host core body temperature during cold exposure.
Baoguo Li, Li Li, Min Li, S. Lam, Guanlin Wang, Yingga Wu, Hanlin Zhang, Chaoqun Niu, Xueying Zhang, Xue Liu, C. Hambly, W. Jin, G. Shui, J. Speakman   +13 more
semanticscholar   +1 more source

Brown Adipose Tissue, Diet-Induced Thermogenesis, and Thermogenic Food Ingredients: From Mice to Men

Frontiers in Endocrinology, 2020
Since the recent rediscovery of brown adipose tissue (BAT) in adult humans, this thermogenic tissue has been attracting increasing interest. The inverse relationship between BAT activity and body fatness suggests that BAT, because of its energy ...
M. Saito, Mami Matsushita, T. Yoneshiro, Y. Okamatsu‐Ogura   +3 more
semanticscholar   +1 more source

Intestinal AMPK modulation of microbiota mediates crosstalk with brown fat to control thermogenesis

Nature Communications, 2021
The energy-dissipating capacity of brown adipose tissue through thermogenesis can be targeted to improve energy balance. Mammalian 5′-AMP-activated protein kinase, a key nutrient sensor for maintaining cellular energy status, is a known therapeutic ...
Wendong Huang, Eryun Zhang, Lihua Jin, Yangmeng Wang, Jui Tu, Lili Ding, Zhipeng Fang, Mingjie Fan, I. Al-Abdullah, R. Natarajan, K. Ma, Zhengtao Wang, A. Riggs, Li Yang   +13 more
semanticscholar   +1 more source