Results 71 to 80 of about 65,191 (322)

Fighting obesity by targeting factors regulating beige adipocytes. [PDF]

, 2018
Purpose of reviewThe current review provides an update on secreted factors and mechanisms that promote a thermogenic program in beige adipocytes, and their potential roles as therapeutic targets to fight obesity.Recent findingsWe outline recent studies ...
Koliwad, Suneil K, McQueen, Allison E, Wang, Jen-Chywan   +2 more
core   +1 more source

Repeatability of brown adipose tissue measurements on FDG PET/CT following a simple cooling procedure for BAT activation [PDF]

, 2019
Brown Adipose Tissue (BAT) is present in a significant number of adult humans and can be activated by exposure to cold. Measurement of active BAT presence, activity, and volume are desirable for determining the efficacy of potential treatments intended ...
Crandall, John P, Gajwani, Prateek, Mawhinney, Daniel D, O., Joo H, Sterzer, Fred, Wahl, Richard L   +5 more
core   +2 more sources

Exploring the Potential of Liposomal Delivery of Naringenin and Berberine for Browning Adipose Tissue and Obesity Management

European Journal of Lipid Science and Technology, EarlyView.
Biocompatible and biodegradable liposomes were developed to encapsulate naringenin (N) and berberine (B), enhancing their stability and bioavailability. Their effects on thermogenesis and browning in 3T3‐L1 preadipocyte cells compared to their free forms were investigated.
Elif Didem Örs Demet, Kübra Uçar Baş, Aslıhan Alpaslan, Dilem Tuğal Aslan, Tuba Reçber, Tuğba Gülsün, Mustafa Çelebier, Zeynep Göktaş   +7 more
wiley   +1 more source

Citrus aurantium L. polymethoxyflavones promote thermogenesis of brown and white adipose tissue in high-fat diet induced C57BL/6J mice

Journal of Functional Foods, 2020
Promoting thermogenesis of brown and beige adipocytes increases energy expenditure, which is a critical approach to prevent obesity. In the present study, we elucidated the effect of the citrus polymethoxyflavones on adaptive thermogenesis in high fat ...
Guangning Kou, Yan Hu, Zixiao Jiang, Zhenqing Li, Peiyuan Li, Hongjie Song, Qiyang Chen, Zhiqin Zhou, Quanjun Lyu   +8 more
doaj  

Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice [PDF]

, 2012
Insulin resistance and impaired glucose homoeostasis are important indicators of Type 2 diabetes and are early risk factors of AD (Alzheimer's disease).
Alex J. Harper, Alison D. McNeilly, Almind, Arch, Azzu, Balleza-Tapia, Biessels, Burcelin, Butler, Cai, Cannon, Choi, Cioffi, Cole, Craft, Craft, D. Lee Hamilton, David R. Howlett, De Felice, de la Monte, de la Monte, Dominguez, Folch, Fromme, Frölich, Fukumoto, Harrison, Hassing, Ho, Huse, Ishrut Hussain, Janson, Jennifer Gallagher, John R. Speakman, Judy Latcham, Kirsten A. Bannon, Kobayashi, Kontani, Kus, LaFerla, Laura A. Burgess, Lee, Li, Lobke M. Vaanholt, Luchsinger, Luo, Mensink, Michael L.J. Ashford, Mirshamsi, Paul J. Meakin, Pietrak, Rapoport, Rivera, Roberds, Sankaranarayanan, Selman, Speakman, Steen, Tiraby, Vassar, Vassar, Vattemi, Xie   +62 more
core   +4 more sources

Contextualising Physical Activity Levels in Patients With Anorexia Nervosa: A Systematic Review and Meta‐Analysis

European Eating Disorders Review, EarlyView.
ABSTRACT Background and objective Anorexia nervosa (AN) is a mental disorder most prevalent among adolescent females, with rising cases in younger and more culturally diverse populations. Unhealthy activity patterns are common and have been linked to increased relapse rates; however, data on objectively measured physical activity levels (PALs) in this ...
Álex V. Pagador, Hugo Olmedillas, Danika A. Quesnel, Iván Cavero‐Redondo, María Fernandez‐del‐Valle   +4 more
wiley   +1 more source

DsbA-L deficiency in T cells promotes diet-induced thermogenesis through suppressing IFN-γ production

Nature Communications, 2021
Adipose tissue-resident T cells are known to regulate thermogenesis and energy expenditure. Here the authors report that deletion of mitochondria-localized protein DsbA-L in T cells promotes diet-induced thermogenesis via suppressing IFN-γ production.
Haiyan Zhou, Xinyi Peng, Jie Hu, Liwen Wang, Hairong Luo, Junyan Zhang, Yacheng Zhang, Guobao Li, Yujiao Ji, Jingjing Zhang, Juli Bai, Meilian Liu, Zhiguang Zhou, Feng Liu   +13 more
doaj   +1 more source

Practical utility and reliability of whole-room calorimetry in young children [PDF]

, 2012
The use of whole-room calorimetry (WRC) in young children can increase our understanding of children's energy balance. However, studies using WRC in young children are rare due to concerns about its feasibility.
Anthony D. Okely, Dylan Cliff, John J. Reilly, Marijka Batterham, Rachel A. Jones, Schofield, Søren Brage, Ulf Ekelund, Xanne Janssen   +8 more
core   +2 more sources

Exploring the Potential of Tsuruazuki Bean as a Functional Food to Curb Obesity Using Human Amniotic Epithelial Cells and 3T3‐L1 Preadipocytes

Food Frontiers, EarlyView.
Obesity is a global health problem that requires research and regulatory attention. This research aims to investigate transcriptome‐wide changes induced by Vigna umbellata (Tsuruazuki) using a stem cell‐based tool and preadipocytes to explore its untapped potential as a functional food for anti‐obesity applications.
Elda Nurafnie Ibnu Rasid, Farhana Ferdousi, Kazunori Sasaki, Kyoko Toda, Shinya Takahashi, Mari Maeda‐Yamamoto, Hiroko Isoda   +6 more
wiley   +1 more source

At thermoneutrality, acute thyroxine-induced thermogenesis and pyrexia are independent of UCP1

Molecular Metabolism, 2019
Objective: Hyperthyroidism is associated with increased metabolism (“thyroid thermogenesis”) and elevated body temperature, often referred to as hyperthermia.
Claudia Dittner, Erik Lindsund, Barbara Cannon, Jan Nedergaard   +3 more
doaj