Results 231 to 240 of about 104,127 (354)

Tetravalent antibodies are more potent and efficacious erythropoiesis‐stimulating agents than erythropoietin in vivo

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Recent studies have shown that tetravalent antibodies are potent and efficacious agonists of the erythropoietin (EPO) receptor (EPOR) both in vitro and in vivo. To identify antibody‐based erythropoiesis‐stimulating agents (ESAs) with therapeutic potential, we evaluated various tetravalent antibody formats for EPOR agonism and key biophysical ...
Jarrett J. Adams, Levi L. Blazer, Jacky Chung, Minoo Karimi, Taylor Davidson, Bailey Blair, Carlos Waddle, Craig A. Hokanson, Heather A. Bruce, Alexander U. Singer, Eva‐Maria Tombak, Kiira Gildemann, Nele Tamberg, Kaja Kiiver, Mart Ustav Jr, Yue Ma, Luigi Colombo, Lily Jun‐Shen Huang, Stephen W. Michnick, Orson W. Moe, Sachdev S. Sidhu   +20 more
wiley   +1 more source

Recombinant Forms of α-Amylase AmyBL159 from a Thermophilic Bacterium <i>Bacillus licheniformis</i> MGMM159: The Effect of the Expression System on the Enzyme Properties. [PDF]

Microorganisms
Suleimanova ER, Klochkova EA, Validov SZ, Kolomytseva MP, Chernykh AM, Trachtmann NV.   +5 more
europepmc   +1 more source

Improvement of the rinderpest vaccine thermostability : End of year 1 and 2 report [PDF]

, 1989
Calvez, D., Diallo, Adama, Lefèvre, Pierre-Charles   +2 more
core  

Myoglobin immobilized on Fe3O4@SiO2 magnetic nanoparticles: Direct electron transfer, enhanced thermostability and electroactivity

, 2007
Qin Xu, Xiaojun Bian, Liangliang Li, Xiao Hu, Min Sun, Da Chen, Yang Wang   +6 more
openalex   +2 more sources

Extracellular expression in Bacillus subtilis of a thermostable Geobacillus stearothermophilus lipase

, 2021
Ridwan Elemosho, Antonius Suwanto, Maggy Thenawidjaja   +2 more
openalex   +1 more source

Residue 365 in Hemagglutinin-Neuraminidase Is a Key Thermostable Determinant of Genotype VI.2.1.1.2.2 Newcastle Disease Virus. [PDF]

Viruses
Di T, Zhao R, Shi Q, Wang F, Han Z, Li H, Shao Y, Sun J, Liu S.   +8 more
europepmc   +1 more source

Evaluation of an Alternative Recombinant Thermostable Thermus thermophilus (r Tth )-Based Real-Time Reverse Transcription-PCR Kit for Detection of Rotavirus A [PDF]

, 2017
Eric Katz, Rashi Gautam, Michael D. Bowen   +2 more
openalex   +1 more source

Thermostable Cas9 nucleases

, 2016
Thermostable Cas9 nucleases. The present invention relates to the field of genetic engineering and more particularly to nucleic acid editing and genome modification. The present invention provides an isolated Cas protein or polypeptide fragment thereof having an amino acid sequence of SEQ ID NO: 1 or a sequence of at least 77% identity therewith ...
van der Oost, J., Daas, M.J.A., Kengen, S.W.M., de Vos, W.M.   +3 more
openaire   +1 more source

Synechococcus Under Stress: Contrasting Physiological and Transcriptional Responses to Salinity and Temperature in Marine Versus Euryhaline Strains

Environmental Microbiology Reports, Volume 18, Issue 1, February 2026.
Two model strains of Synechococcus sp.—the marine RS9907 and the euryhaline WH5701—exhibit distinct physiological responses to salinity after long acclimations at optimal and cold growth temperatures. Transcriptomic and photochemical analyses reveal drastic differences in their regulatory strategies and photosynthetic activity across a salinity ...
Isabel Escribano‐Gómez, Rebeca Pérez, Uxue Arrizabalaga, Raquel Liébana, Miriam Vergara‐Len, Ángel López‐Urrutia, Laura Alonso‐Sáez   +6 more
wiley   +1 more source

Some Like It Hot –Structural Changes in Extremophile Rubredoxin at 120 °C

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
We reveal the high temperature crystal structure of a hyperthermophilic (Pyrococcus furiosus) rubredoxin at 393 K (120 °C), together with multiple complementary structures down to 100 K. The results are compared with molecular dynamics calculations. Significant changes in H‐bonding are observed.
Tzanko Doukov, Igor Leontyev, Francis E. Jenney Jr., Dominic George, Stephen P. Cramer   +4 more
wiley   +2 more sources