Results 31 to 40 of about 18,156 (205)

Synthesis, Anticancer Activity and Carbonic Anhydrase Inhibitory Activity of new Thiadiazole-hydrazone Derivatives

open access: yesCumhuriyet Science Journal, 2023
In five steps, new compounds 5a, 5b of thiadiazole-hydrazone derivatives were synthesized. Various spectral methods, such as 1H NMR, 13C NMR, and elemental analyses, were used to clarify the structures of the compounds. Three cancer cell lines (MCF7, MDA,
Ulviye Acar Çevik   +1 more
doaj   +1 more source

Red Phosphorescence from Benzo[2,1,3]thiadiazoles at Room Temperature [PDF]

open access: yes, 2016
We describe the red phosphorescence exhibited by a class of structurally simple benzo[2,1,3]thiadiazoles at room temperature. The photophysical properties of these molecules in deoxygenated cyclohexane, including their absorption spectra, steady-state ...
Graham T. Sazama   +7 more
core   +2 more sources

trans-Diaquabis[2,5-bis(pyridin-2-yl)-1,3,4-thiadiazole]nickel(II) bis(tetrafluoridoborate)

open access: yesActa Crystallographica Section E, 2011
The bidentate 1,3,4-thiadiazole ligand, namely, 2,5-bis(2-pyridyl)-1,3,4-thiadiazole (denoted L), untested as a polydentate ligand, has been found to form the monomeric title complex, [Ni(C12H8N4S)2(H2O)2](BF4)2.
Fouad Bentiss   +4 more
doaj   +1 more source

Functionalization of Silicon Surface by Thiadiazole Molecule : a DFT Study

open access: yes, 2018
The first principles density functional theory (DFT) calculations have been used to investigate the atomic and electronic properties of thiadiazole adsorption on the Si(001) surface.
Kaderoglu, Cagil
core   +1 more source

Assessment of pharmacological activity and bioavailability of the new derivative 1,3,4-thiadiazole [PDF]

open access: yes, 2018
Acexazolamide is a new derivative of 1,3,4-thiadiazole and acexamic acid. In animal experiments, acute toxicity, pharmacological activity and bioavailability of acexazolamide were ...
Demidova, M. A.   +2 more
core   +2 more sources

Antifungal Activity, Cytotoxicity and Mechanism of Action of Nitroheteroaryl-1,3,4-thiadiazole Containing N-benzyl and N-methoxyethyl Substitution Against Aspergillus fumigatus

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2021
Introduction: This study aimed to evaluate antifungal activity and cytotoxicity of two new nitroheteroaryl-1,3,4-thiadiazole derivatives containing N-methoxyethyl (9) and N-benzyl (10) moiety against Aspergillus fumigatus with a special focus on their ...
Pegah MORADABAD   +5 more
doaj   +1 more source

Formation of Pyrazol-1,3,4-Thiadiazoles through 1,3-Dipolar Cycloadditions of 3-Thioxo-[1,2,4]-Triazepin-5-one with Nitrilimines: An Experimental and Computational study [PDF]

open access: yes, 2009
In this work the results of experimental and computational study of the title compounds and some ancillary compounds are reported. Two bicyclic pyrazol-1,3,4-thiadiazole derivatives were synthesized by reaction between 6-dimethylaminomethylene-3-thioxo-
Azzouzi, S.   +7 more
core   +2 more sources

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

open access: yesAngewandte Chemie, Volume 138, Issue 10, 2 March 2026.
Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f. Rhomboid proteases are a mechanistically unique and evolutionarily conserved protein family. Despite their pharmacological relevance, the development of selective inhibitors has lagged behind that of soluble proteases.
Claudia Bohg   +21 more
wiley   +2 more sources

New Route Synthesis of Thiadiazoles, Bisthiadiazoles, Thiadiazolotriazines, and Pyrazolothiadiazoles Based on Hydrazonoyl Halides and Dihydrazinylthiadiazole

open access: yesMolecules, 2017
Synthesis and characterization of new thiadiazoles, bisthiadiazoles from the reaction of mono- and di-hydrazonoyl halides with various hydrazinecarbodithioate derivatives were studied.
Abdelwahed R. Sayed, Shar Saad Al-Shihry
doaj   +1 more source

Excitation Dynamics in Low Band Gap Donor-Acceptor Copolymers and Blends

open access: yes, 2012
Donor-acceptor (D-A) type copolymers show great potential for the application in the active layer of organic solar cells. Nevertheless the nature of the excited states, the coupling mechanism and the relaxation pathways following photoexcitation are yet ...
Deibel, Carsten   +7 more
core   +1 more source

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