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Thiadiazoles

Heterocycles containing nitrogen, oxygen and sulfur have been under investigation for a long time because of their important medicinal properties. The literature survey has described that thiadiazole moieties serve as analgesic, anti-inflammatory, anti-microbial activities, antihypertensive,anticancer, antituberculosis and vasodilator and this ...
G. Nagendra   +3 more
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Synthesis and Molecular Docking of Some Novel Thiazoles and Thiadiazoles Incorporating Pyranochromene Moiety as Potent Anticancer Agents.

Mini-Reviews in Medical Chemistry, 2018
BACKGROUND Chemotherapy has become one of the methods that are being adopted to treat cancer. Coumarins, thiazoles and thiadiazoles are versatile synthetic scaffolds possessing wide spectrum of biological effects including potential anticancer activity.
Sobhi M. Gomha   +4 more
semanticscholar   +1 more source

1,3,4‐Thiadiazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Cascade Trisulfur Radical Anion (S3•-) Addition/Electron Detosylation Process for the Synthesis of 1,2,3-Thiadiazoles and Isothiazoles.

Journal of Organic Chemistry, 2018
Trisulfur radical anion (S3•-) mediated reactions with in situ formed azoalkenes and α,β-usaturated N-sulfonylimines for the construction of 1,2,3-thiadiazoles and isothiazoles has been developed.
Bei-bei Liu   +4 more
semanticscholar   +1 more source

Liquid crystalline thiadiazole derivatives: new ferroelectric thiadiazole derivatives

Liquid Crystals, 2002
A series of optically active thiadiazole Schiff's bases were prepared and their liquid crystalline properties were studied. Chirality was achieved by introducing an asymmetric carbon atom into the alkoxy group. Thus, 2-(p -active-alkoxyphenyl-imine)-5-(p-n-alkoxy)phenyl-1,3,4-thiadiazoles were synthesized.
Yan Xu   +5 more
openaire   +1 more source

Synthesis, Antimicrobial Evaluation of Some New 1, 3, 4-Thiadiazoles and 1, 3, 4- Thiadiazines

Current Organic Synthesis, 2018
1, 3, 4-thiadiazoles, 1, 3, 4-thiadiazines and thienopyrimidines have newly attracted attention due to their forceful pharmacological activities. They showed antimicrobial, antiviral, analgesic and anti-inflammatory properties.
A. Abu‐Hashem, Rasha A. M. Faty
semanticscholar   +1 more source

Alkynylated Aceno[2,1,3]thiadiazoles

Organic Letters, 2009
Enlarged acenothiadiazoles, which are easily prepared, display attractive optical and electrochemical properties. The annulation of thiadiazole to anthracene gives a stable material with optical properties similar to those of substituted pentacenes.
Anthony Lucas, Appleton   +8 more
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Thiadiazole-Derived Expanded Heteroazaporphyrinoids

Organic Letters, 2001
[structure: see text] Heteroannulenes 1 and 3 containing three subunits of isoindole or pyrrole, respectively, three 1,3,4-thiadiazole moieties, and six aza-bridges have been synthesized by reaction of the corresponding diiminoisoindoline or diiminopyrroline with 2,5-diamino-1,3,4-thiadiazole.
M K, Islyaikin   +4 more
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1,2,4-Thiadiazole

2015
[288-92-6] C2H2N2S (MW 86.11) InChI = 1S/C2H2N2S/c1-3-2-5-4-1/h1-2H InChIKey = YGTAZGSLCXNBQL-UHFFFAOYSA-N (prepared from 5-bromo-1,2,4-thiadiazole) Alternate Name(s): 1-thia-2,4-diazacyclopentadiene; 2,4-diazathiophene. Physical Data: mp −33 to −35 °C, bp753 120.7–121.2 °C, d 1.3298 g mL−1 at 20 °C, 1.5316; λmax 229 nm ...
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Recent Advances in the Synthesis of Thiadiazoles

Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry, 2019
Thiadiazole moieties are present in many natural products and pharmaceutical compounds that possess a broad spectrum of biological activities, serving as antidepressant, anxiolytic, antimicrobial, antitubercular, antiinflammatory, antidiabetic ...
Yan Xiao   +3 more
semanticscholar   +1 more source

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