Results 1 to 10 of about 60,226 (297)

Thiamine, gastrointestinal beriberi and acetylcholine signaling [PDF]

Frontiers in Nutrition
Research has highlighted numerous detrimental consequences of thiamine deficiency on digestive function. These range from impaired gastric and intestinal motility to aberrant changes in pancreatic exocrine function, gastric acidity and disturbances in ...
Elliot Overton, Alina Emelyanova, Victoria I. Bunik, Victoria I. Bunik, Victoria I. Bunik   +4 more
doaj   +2 more sources

Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3 [PDF]

Nature Communications
Thiamine and pyridoxine are essential B vitamins that serve as enzymatic cofactors in energy metabolism, protein and nucleic acid biosynthesis, and neurotransmitter production.
Peipei Li, Zhini Zhu, Yong Wang, Xuyuan Zhang, Chuanhui Yang, Yalan Zhu, Zixuan Zhou, Yulin Chao, Yonghui Long, Yina Gao, Songqing Liu, Liguo Zhang, Pu Gao, Qianhui Qu   +13 more
doaj   +2 more sources

Thiamin [PDF]

Advances in Nutrition, 2017
Thiamin, sometimes called vitamin B1, is essential in carbohydrate metabolism and neural function. It is widely distributed in foods, although cereal grains contribute the greatest levels to most human diets. It is water soluble and is absorbed through both active transport and passive diffusion.
Jennifer C, Kerns, Jean L, Gutierrez
openaire   +4 more sources

Reduced Thiamine Availability and Hyperglycemia Impair Thiamine Transport in Renal Glomerular Cells through Modulation of Thiamine Transporter 2

Biomedicines, 2021
Thiamine helps transketolase in removing toxic metabolites, counteracting high glucose-induced damage in microvascular cells, and progression of diabetic retinopathy/nephropathy in diabetic animals.
Aurora Mazzeo, Federica Barutta, Linda Bellucci, Marina Trento, Gabriella Gruden, Massimo Porta, Elena Beltramo   +6 more
doaj   +1 more source

Thiamine Supplementation Improves Survival and Body Condition of Hatchery-Reared Steelhead (Oncorhynchus mykiss) in Oregon

Veterinary Sciences, 2023
Early rearing of steelhead (Oncorhynchus mykiss) in Oregon hatcheries is often problematic; fry can become emaciated and die during the period between hatch and first feed. Thiamine (vitamin B1) deficiency has caused early mortality in salmonids; however,
Aimee N. Reed, Freya E. Rowland, Jennifer A. Krajcik, Donald E. Tillitt   +3 more
doaj   +1 more source

Thiamine diphosphate in whole blood, thiamine and thiamine monophosphate in breast-milk in a refugee population. [PDF]

PLoS ONE, 2012
The provision of high doses of thiamine may prevent thiamine deficiency in the post-partum period of displaced persons.The study aimed to evaluate a supplementation regimen of thiamine mononitrate (100 mg daily) at the antenatal clinics in Maela refugee ...
Wolfgang Stuetz, Verena Ilona Carrara, Rose McGready, Sue Jean Lee, Hans Konrad Biesalski, François Henry Nosten   +5 more
doaj   +1 more source

High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice. [PDF]

PLoS ONE, 2017
SLC19A3 deficiency, also called thiamine metabolism dysfunction syndrome-2 (THMD2; OMIM 607483), is an autosomal recessive neurodegenerative disorder caused by mutations in SLC19A3, the gene encoding thiamine transporter 2.
Kaoru Suzuki, Kenichiro Yamada, Yayoi Fukuhara, Ai Tsuji, Katsumi Shibata, Nobuaki Wakamatsu   +5 more
doaj   +1 more source

Effect of pH and concentration on the chemical stability and reaction kinetics of thiamine mononitrate and thiamine chloride hydrochloride in solution

BMC Chemistry, 2021
Thiamine (vitamin B1) is an essential micronutrient in the human diet, found both naturally and as a fortification ingredient in many foods and supplements.
Adrienne L. Voelker, Lynne S. Taylor, Lisa J. Mauer   +2 more
doaj   +1 more source

Application of Fe3O4/thiamine Magnetic Particles in the Removal of Methylene Blue

Applied Environmental Research, 2023
Fe3O4/thiamine particles were prepared in this work via precipitation method. The synthesis method is based on the principle of precipitation of Fe3O4 particles in the presence of thiamine coating agent.
Lan Tran-Nguyen, Suong Mai-Thi-Thu, Thanh-Ty Nguyen, Kim-Phung Ly, Luu-Ngoc-Hanh Cao, Tran Thi Bich Quyen, Shella Permatasari Santoso, Nguyen-Phuong-Dung Tran, Nguyen Minh Nhut   +8 more
doaj   +1 more source

The Impacts of Slc19a3 Deletion and Intestinal SLC19A3 Insertion on Thiamine Distribution and Brain Metabolism in the Mouse

Metabolites, 2023
The Thiamine Transporter 2 (THTR2) encoded by SLC19A3 plays an ill-defined role in the maintenance of tissue thiamine, thiamine monophosphate, and thiamine diphosphate (TDP) levels. To evaluate the impact of THTR2 on tissue thiamine status and metabolism,
Anita Wen, Ying Zhu, Sook Wah Yee, Brian I. Park, Kathleen M. Giacomini, Andrew S. Greenberg, John W. Newman   +6 more
doaj   +1 more source