Advances in Nutrition, 2017 Thiamin, sometimes called vitamin B1, is essential in carbohydrate metabolism and neural function. It is widely distributed in foods, although cereal grains contribute the greatest levels to most human diets. It is water soluble and is absorbed through both active transport and passive diffusion.
Jennifer C, Kerns, Jean L, Gutierrez
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Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]
, 2012 Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
A Adaikalakoteswari +42 more
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Reduced thiamine availability and hyperglycemia impair thiamine transport in renal glomerular cells through modulation of thiamine transporter 2 [PDF]
, 2021 Thiamine helps transketolase in removing toxic metabolites, counteracting high glucose-induced damage in microvascular cells, and progression of diabetic retinopathy/nephropathy in diabetic animals.
Barutta, F. +6 more
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Low-dose thiamine supplementation of lactating Cambodian mothers improves human milk thiamine concentrations: a randomized controlled trial. [PDF]
, 2021 BACKGROUND: Infantile beriberi-related mortality is still common in South and Southeast Asia. Interventions to increase maternal thiamine intakes, and thus human milk thiamine, are warranted; however, the required dose remains unknown.
Allen, Lindsay H +19 more
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Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults. [PDF]
, 2019 Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Adams +154 more
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Severe thiamine deficiency in eastern Baltic cod (Gadus morhua) [PDF]
, 2020 The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation, lower ...
Balk, Lennart +6 more
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THIAMINE – INDUCED FORMATION OF THE MONOPYRROLE MOIETY OF PRODIGIOSIN [PDF]
, 2021 Thiamine stimulates the production of a red pigment , which is chromatographically and spectrophotometrically identical to prodigiosin , by growing cultures of serratia marcescens mutant 9-3-3 .
Ahmed, Zeena F. +2 more
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Severe acute axonal neuropathy following treatment with arsenic trioxide for acute promyelocytic leukemia: a case report [PDF]
, 2016 Peripheral neuropathy is a common complication of arsenic toxicity. Symptoms are usually mild and reversible following discontinuation of treatment. A more severe chronic sensorimotor polyneuropathy characterized by distal axonal-loss neuropathy can be ...
Kuhn, Marcus +3 more
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Glutamine Phosphoribosylpyrophosphate Amidotransferase-independent Phosphoribosyl Amine Synthesis from Ribose 5-Phosphate and Glutamine or Asparagine [PDF]
, 2007 Phosphoribosylamine (PRA) is the first intermediate in the common pathway to purines and thiamine and is generated in bacteria by glutamine phosphoribosylpyrophosphate (PRPP) amidotransferase (EC 2.4.2.14) from PRPP and glutamine.
Downs, Diana M. +2 more
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Quantitative analysis of oxidized vitamin B1 metabolites generated by hypochlorous acid [PDF]
, 2020 Thiamine, a water-soluble essential vitamin known as vitamin B1, acts as an important cofactor in various cellular processes, such as metabolism and energy production. Thiamine is also thought to have antioxidant effects as a singlet oxygen scavenger and
102043 +7 more
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