Results 1 to 10 of about 2,146 (116)

Thiamine diphosphate in whole blood, thiamine and thiamine monophosphate in breast-milk in a refugee population.

PLoS ONE, 2012
BackgroundThe provision of high doses of thiamine may prevent thiamine deficiency in the post-partum period of displaced persons.Methodology/principal findingsThe study aimed to evaluate a supplementation regimen of thiamine mononitrate (100 mg daily) at
Wolfgang Stuetz, Verena Ilona Carrara, Rose McGready, Sue Jean Lee, Hans Konrad Biesalski, François Henry Nosten   +5 more
doaj   +4 more sources

Thiamine Status in Humans and Content of Phosphorylated Thiamine Derivatives in Biopsies and Cultured Cells [PDF]

PLoS ONE, 2010
BACKGROUND: Thiamine (vitamin B1) is an essential molecule for all life forms because thiamine diphosphate (ThDP) is an indispensable cofactor for oxidative energy metabolism.
Didier Martin, Lucien Bettendorff, Bernard Lakaye   +2 more
exaly   +2 more sources

Reduced Thiamine Availability and Hyperglycemia Impair Thiamine Transport in Renal Glomerular Cells through Modulation of Thiamine Transporter 2

Biomedicines, 2021
Thiamine helps transketolase in removing toxic metabolites, counteracting high glucose-induced damage in microvascular cells, and progression of diabetic retinopathy/nephropathy in diabetic animals.
Aurora Mazzeo, Federica Barutta, Linda Bellucci, Marina Trento, Gabriella Gruden, Massimo Porta, Elena Beltramo   +6 more
doaj   +1 more source

Thiamine Supplementation Improves Survival and Body Condition of Hatchery-Reared Steelhead (Oncorhynchus mykiss) in Oregon

Veterinary Sciences, 2023
Early rearing of steelhead (Oncorhynchus mykiss) in Oregon hatcheries is often problematic; fry can become emaciated and die during the period between hatch and first feed. Thiamine (vitamin B1) deficiency has caused early mortality in salmonids; however,
Aimee N. Reed, Freya E. Rowland, Jennifer A. Krajcik, Donald E. Tillitt   +3 more
doaj   +1 more source

High-dose thiamine prevents brain lesions and prolongs survival of Slc19a3-deficient mice. [PDF]

PLoS ONE, 2017
SLC19A3 deficiency, also called thiamine metabolism dysfunction syndrome-2 (THMD2; OMIM 607483), is an autosomal recessive neurodegenerative disorder caused by mutations in SLC19A3, the gene encoding thiamine transporter 2.
Kaoru Suzuki, Kenichiro Yamada, Yayoi Fukuhara, Ai Tsuji, Katsumi Shibata, Nobuaki Wakamatsu   +5 more
doaj   +1 more source

Effect of pH and concentration on the chemical stability and reaction kinetics of thiamine mononitrate and thiamine chloride hydrochloride in solution

BMC Chemistry, 2021
Thiamine (vitamin B1) is an essential micronutrient in the human diet, found both naturally and as a fortification ingredient in many foods and supplements.
Adrienne L. Voelker, Lynne S. Taylor, Lisa J. Mauer   +2 more
doaj   +1 more source

Thiamine transporter 2 is involved in high glucose-induced damage and altered thiamine availability in cell models of diabetic retinopathy

Diabetes & Vascular Disease Research, 2020
Thiamine prevents high glucose-induced damage in microvasculature, and progression of retinopathy and nephropathy in diabetic animals. Impaired thiamine availability causes renal damage in diabetic patients. Two single-nucleotide polymorphisms in SLC19A3
Elena Beltramo, Aurora Mazzeo, Tatiana Lopatina, Marina Trento, Massimo Porta   +4 more
doaj   +1 more source

Severe thiamine deficiency in eastern Baltic cod (Gadus morhua).

PLoS ONE, 2020
The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation, lower ...
Josefin Engelhardt, Oscar Frisell, Hanna Gustavsson, Tomas Hansson, Rajlie Sjöberg, Tracy K Collier, Lennart Balk   +6 more
doaj   +1 more source

Association of thiamine administration and prognosis in critically ill patients with heart failure

Frontiers in Pharmacology, 2023
Background: Thiamine deficiency is common in patients with heart failure, and thiamine supplement can benefit these patients. However, the association between thiamine administration and prognosis among critically ill patients with heart failure remains ...
Rui Yang, Jiasheng Huang, Jiasheng Huang, Yumei Zhao, Yumei Zhao, Jia Wang, Dongdong Niu, Enlin Ye, Suru Yue, Suru Yue, Xuefei Hou, Xuefei Hou, Lili Cui, Jiayuan Wu, Jiayuan Wu   +14 more
doaj   +1 more source

Scientific Opinion on the safety and efficacy of vitamin B1 (thiamine mononitrate and thiamine hydrochloride) as a feed additive for all animal species based on a dossier submitted by Lohmann Animal Health

EFSA Journal, 2011
Thiamine mononitrate administered via feed and thiamine hydrochloride via feed or water for drinking are safe for the target animals having a wide margin of safety.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source