Results 21 to 30 of about 89,035 (286)

Effect of Ascorbic Acid, Corticosteroids, and Thiamine on Organ Injury in Septic Shock: The ACTS Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance The combination of ascorbic acid, corticosteroids, and thiamine has been identified as a potential therapy for septic shock. Objective To determine whether the combination of ascorbic acid, corticosteroids, and thiamine attenuates organ ...
A. Moskowitz, David T. Huang, P. Hou, Jonathan Gong, P. Doshi, A. Grossestreuer, L. Andersen, L. Ngo, R. Sherwin, K. Berg, M. Chase, M. Cocchi, Jessica B. McCannon, Mark A. Hershey, A. Hilewitz, M. Korotun, L. Becker, R. Otero, J. Uduman, Ayan Sen, M. Donnino   +20 more
semanticscholar   +1 more source

Hiding in Plain Sight: Modern Thiamine Deficiency

Cells, 2021
Thiamine or vitamin B1 is an essential, water-soluble vitamin required for mitochondrial energetics—the production of adenosine triphosphate (ATP). It is a critical and rate-limiting cofactor to multiple enzymes involved in this process, including those ...
C. Marrs, D. Lonsdale
semanticscholar   +1 more source

Association between levels of thiamine intake, diabetes, cardiovascular diseases and depression in Korea: a national cross-sectional study

Journal of Nutritional Science, 2021
The present study aimed to determine thiamine intake levels and the association between thiamine intake, diabetes, cardiovascular diseases and mental health.
H. Duc, Hojin Oh, In Mo Yoon, Min-Sun Kim   +3 more
semanticscholar   +1 more source

Neuroprotective Effects of Thiamine and Precursors with Higher Bioavailability: Focus on Benfotiamine and Dibenzoylthiamine

International Journal of Molecular Sciences, 2021
Thiamine (vitamin B1) is essential for brain function because of the coenzyme role of thiamine diphosphate (ThDP) in glucose and energy metabolism. In order to compensate thiamine deficiency, several thiamine precursors with higher bioavailability were ...
M. Sambon, P. Wins, L. Bettendorff
semanticscholar   +1 more source

Application of Fe3O4/thiamine Magnetic Particles in the Removal of Methylene Blue

Applied Environmental Research, 2023
Fe3O4/thiamine particles were prepared in this work via precipitation method. The synthesis method is based on the principle of precipitation of Fe3O4 particles in the presence of thiamine coating agent.
Lan Tran-Nguyen, Suong Mai-Thi-Thu, Thanh-Ty Nguyen, Kim-Phung Ly, Luu-Ngoc-Hanh Cao, Tran Thi Bich Quyen, Shella Permatasari Santoso, Nguyen-Phuong-Dung Tran, Nguyen Minh Nhut   +8 more
doaj   +1 more source

The Impacts of Slc19a3 Deletion and Intestinal SLC19A3 Insertion on Thiamine Distribution and Brain Metabolism in the Mouse

Metabolites, 2023
The Thiamine Transporter 2 (THTR2) encoded by SLC19A3 plays an ill-defined role in the maintenance of tissue thiamine, thiamine monophosphate, and thiamine diphosphate (TDP) levels. To evaluate the impact of THTR2 on tissue thiamine status and metabolism,
Anita Wen, Ying Zhu, Sook Wah Yee, Brian I. Park, Kathleen M. Giacomini, Andrew S. Greenberg, John W. Newman   +6 more
doaj   +1 more source

Association of thiamine administration and prognosis in critically ill patients with heart failure

Frontiers in Pharmacology, 2023
Background: Thiamine deficiency is common in patients with heart failure, and thiamine supplement can benefit these patients. However, the association between thiamine administration and prognosis among critically ill patients with heart failure remains ...
Rui Yang, Jiasheng Huang, Jiasheng Huang, Yumei Zhao, Yumei Zhao, Jia Wang, Dongdong Niu, Enlin Ye, Suru Yue, Suru Yue, Xuefei Hou, Xuefei Hou, Lili Cui, Jiayuan Wu, Jiayuan Wu   +14 more
doaj   +1 more source

Thiamine deficiency disorders: a clinical perspective

Annals of the New York Academy of Sciences, 2020
Thiamine is an essential water‐soluble vitamin that plays an important role in energy metabolism. Thiamine deficiency presents many challenges to clinicians, in part due to the broad clinical spectrum, referred to as thiamine deficiency disorders (TDDs),
T. J. Smith, Casey R. Johnson, R. Koshy, S. Hess, U. Qureshi, Mimi Lhamu Mynak, P. Fischer   +6 more
semanticscholar   +1 more source

Evaluation of thiamine as adjunctive therapy in COVID-19 critically ill patients: a two-center propensity score matched study

Critical Care, 2021
Thiamine is a precursor of the essential coenzyme thiamine pyrophosphate required for glucose metabolism; it improves the immune system function and has shown to reduce the risk of several diseases.
Khalid A. Al Sulaiman, Ohoud A. Aljuhani, Maram Al Dossari, Asma Alshahrani, A. Alharbi, Rahmah A Algarni, Majed Al Jeraisy, Shmeylan A. Al Harbi, Abdulmalik Al Katheri, Fahad A. Al Eidan, Abdulkareem M. Al Bekairy, Nouf Al Qahtani, Mashael Al Muqrin, R. Vishwakarma, Ghassan Al Ghamdi   +14 more
semanticscholar   +1 more source

Combination therapy of vitamin C and thiamine for septic shock: a multi-centre, double-blinded randomized, controlled study

Intensive Care Medicine, 2020
To evaluate the effects of early combination therapy with intravenous vitamin C and thiamine on recovery from organ failure in patients with septic shock.
S. Hwang, S. Ryoo, Jong Eun Park, Y. Jo, Dong-Hyun Jang, G. Suh, Taegyun Kim, Youn-Jung Kim, Seonwoo Kim, Hyun Cho, I. Jo, S. Chung, Sung-Hyuk Choi, T. Shin, W. Kim   +14 more
semanticscholar   +1 more source