Results 41 to 50 of about 89,035 (286)

Is it time to reconsider the administration of thiamine alone or in combination with vitamin C in critically ill patients? A meta-analysis of clinical trial studies

Journal of Intensive Care, 2022
Highlights Thiamine, co-supplementation of thiamine and vitamin C and co-administration of hydrocortisone, vitamin C and thiamine (HVT) had no significant effect on free days of ventilation and ICU length of stay.
Nafiseh Shokri-mashhadi, Ali Aliyari, Zahra Hajhashemy, Saeed Saadat, Mohammad Hossein Rouhani   +4 more
doaj   +1 more source

Low-dose thiamine supplementation of lactating Cambodian mothers improves human milk thiamine concentrations: a randomized controlled trial

American Journal of Clinical Nutrition, 2021
Background Infantile beriberi–related mortality is still common in South and Southeast Asia. Interventions to increase maternal thiamine intakes, and thus human milk thiamine, are warranted; however, the required dose remains unknown.
Jelisa Gallant, Kathleen Chan, T. Green, F. Wieringa, S. Leemaqz, Rem Ngik, Jeffrey R Measelle, Dare A. Baldwin, Mam Borath, Prak Sophonneary, L. Yelland, Daniela Hampel, S. Shahab-Ferdows, L. Allen, K. Jones, A. Koulman, Damon A Parkington, Sarah R Meadows, H. Kroeun, Kyly C. Whitfield   +19 more
semanticscholar   +1 more source

High-dose thiamine strategy in Wernicke–Korsakoff syndrome and related thiamine deficiency conditions associated with alcohol use disorder

Indian Journal of Psychiatry, 2021
Thiamine is essential for the activity of several enzymes associated with energy metabolism in humans. Chronic alcohol use is associated with deficiency of thiamine along with other vitamins through several mechanisms.
S. Praharaj, R. Munoli, S. Shenoy, S. Udupa, L. S. Thomas   +4 more
semanticscholar   +1 more source

The role of thiamine as a resuscitator in patients with nonalcoholic medical and CNS disorders

Southwest Respiratory and Critical Care Chronicles, 2017
Thiamine (vitamin B1), a water-soluble vitamin, is an essential factor in cellular metabolism and fundamental cofactor in important biochemical cycles.
Mohamed Shehab-Eldin
doaj   +1 more source

Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine. [PDF]

PLoS ONE, 2012
Thiamine (Vitamin B1) is an essential vitamin that must be obtained from the diet for proper neurological function. At higher doses, thiamine and benfotiamine (S-benzoylthiamine O-monophosphate, BT)-a phosphorylated derivative of thiamine-have ...
Julie K Hurt, Jennifer L Coleman, Brendan J Fitzpatrick, Bonnie Taylor-Blake, Arlene S Bridges, Pirkko Vihko, Mark J Zylka   +6 more
doaj   +1 more source

THIAMINE DEFICIENCY AND ITS MANAGEMENT IN CRITICAL STATES

Вестник анестезиологии и реаниматологии, 2018
The level of thiamine in critically ill patients can be low due to the loss of fluid, nutrition disorders and increased metabolism. The deficiency of thiamine is associated with reduction of respiratory metabolism, increase in lactate level and ...
V. V. Lomivorotov, M. N. Deryagin, M. N. Abubakirov, E. V. Fominskiy, V. A. Nepomnyaschikh   +4 more
doaj   +1 more source

Thiamine deficiency disorders: diagnosis, prevalence, and a roadmap for global control programs

Annals of the New York Academy of Sciences, 2018
Thiamine is an essential micronutrient that plays a key role in energy metabolism. Many populations worldwide may be at risk of clinical or subclinical thiamine deficiencies, due to famine, reliance on staple crops with low thiamine content, or food ...
Kyly C. Whitfield, M. Bourassa, B. Adamolekun, Gilles Bergeron, L. Bettendorff, K. Brown, L. Cox, A. Fattal-Valevski, P. Fischer, E. L. Frank, L. Hiffler, Lwin Mar Hlaing, M. Jefferds, H. Kapner, S. Kounnavong, Maral P. S. Mousavi, D. Roth, M. Tsaloglou, F. Wieringa, G. Combs   +19 more
semanticscholar   +1 more source

Thiamine and benfotiamine protect neuroblastoma cells against paraquat and β-amyloid toxicity by a coenzyme-independent mechanism

Heliyon, 2019
Background: Benfotiamine (BFT) is a synthetic thiamine precursor with high bioavailability. It is efficient in treating complications of type 2 diabetes and has beneficial effects in mouse models of neurodegenerative diseases.
Margaux Sambon, Aurore Napp, Alice Demelenne, Julie Vignisse, Pierre Wins, Marianne Fillet, Lucien Bettendorff   +6 more
doaj   +1 more source

A novel PET tracer 18F-deoxy-thiamine: synthesis, metabolic kinetics, and evaluation on cerebral thiamine metabolism status

EJNMMI Research, 2020
Background Some neuropsychological diseases are associated with abnormal thiamine metabolism, including Korsakoff–Wernicke syndrome and Alzheimer’s disease.
Changpeng Wang, Siwei Zhang, Yuefei Zou, Hongzhao Ma, Donglang Jiang, Lei Sheng, Shaoming Sang, Lirong Jin, Yihui Guan, Yuan Gui, Zhihong Xu, Chunjiu Zhong   +11 more
doaj   +1 more source

Thiamine status in humans and content of phosphorylated thiamine derivatives in biopsies and cultured cells. [PDF]

PLoS ONE, 2010
BACKGROUND: Thiamine (vitamin B1) is an essential molecule for all life forms because thiamine diphosphate (ThDP) is an indispensable cofactor for oxidative energy metabolism.
Marjorie Gangolf, Jan Czerniecki, Marc Radermecker, Olivier Detry, Michelle Nisolle, Caroline Jouan, Didier Martin, Frédéric Chantraine, Bernard Lakaye, Pierre Wins, Thierry Grisar, Lucien Bettendorff   +11 more
doaj   +1 more source