Results 51 to 60 of about 60,963 (256)

Conserved Phosphorylation of the Myosin1e TH1 Domain Impacts Membrane Association and Function in Yeast and Worms

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cells have an intrinsic ability to rapidly respond to environmental change to regulate cell cycle progression and membrane organisation, thereby affecting cell growth and division. The actin cytoskeleton is a highly dynamic complex of proteins that can rapidly reorganise to change the growth pattern of a cell.
Holly R. Brooker   +7 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Mechanisms of Flavor Substance Formation in Pengqi Sauce Based On an Integrated Analysis of Absolute Microbial Quantification and Volatomics

open access: yesFood Frontiers, EarlyView.
Elucidating flavor compound formation mechanisms in Pengqi sauce through a combinatorial approach integrating absolute microbial community quantification and volatomics profiling. ABSTRACT Pengqi sauce is a traditional Chinese naturally fermented aquatic product, and its unique flavor formation mechanism is closely related to microbial function.
Xiaojie Hou   +7 more
wiley   +1 more source

Deciphering of nutritional profile, therapeutic potential, and networking of bioactive compounds of Moringa oleifera: A comprehensive review

open access: yesFood Biomacromolecules, EarlyView.
The graphical abstract signifies the nutritional profile of various parts of the Moringa oleifera plant, including dried leaves, fresh leaves, leaf powder, seeds, and pods; along with it’s bioactive substance and protein profiling of aqueous concentrates derived from the fruit, seed, and leaf.
Rajesh Kumar   +5 more
wiley   +1 more source

Pre-analytical challenges from adsorptive losses associated with thiamine analysis

open access: yesScientific Reports
Thiamine (vitamin B1) is an essential vitamin serving in its diphosphate form as a cofactor for enzymes in the citric acid cycle and pentose-phosphate pathways.
Katie A. Edwards   +4 more
doaj   +1 more source

Pathway Editing Targets for Thiamine Biofortification in Rice Grains

open access: yesFrontiers in Plant Science, 2018
Thiamine deficiency is common in populations consuming polished rice as a major source of carbohydrates. Thiamine is required to synthesize thiamine pyrophosphate (TPP), an essential cofactor of enzymes of central metabolism. Its biosynthesis pathway has
Anu P. Minhas, Rakesh Tuli, Sanjeev Puri
doaj   +1 more source

Thiamine Metabolites and Dementia? [PDF]

open access: yesEBioMedicine, 2016
The determinants of amyloid deposition in the brain, increased intracerebral phosphorylated tau, hippocampal atrophy, and loss of synapses in areas of brain (the pathogenic determinants of most dementia) remain undetermined except for Mendelian genetic disorders and higher risk of both amyloid deposition and dementia among individuals who carry the ...
openaire   +4 more sources

The impact and management of hyperemesis gravidarum: Current and future perspectives

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy affecting around 1%–3% of pregnancies worldwide and is the most common reason for hospital admission in early pregnancy. HG can have lasting consequences for both pregnant individuals and their offspring.
L. M. van der Minnen   +4 more
wiley   +1 more source

Multi‐omics insights into surface charge effects to decode the interplay of nanoplastics and bacterial antibiotic resistance

open access: yesiMeta, EarlyView.
Multi‐omics approaches revealed how nanoplastics with different surface charges influence antibiotic resistance in Escherichia coli K12. Positively charged nanoplastics enhanced antibiotic resistance by upregulating genes and proteins linked to oxidative stress tolerance and efflux pumps, and promoted antibiotic resistance genes transfer via ...
Houyu Li, Yinuo Ding, Yan Xu, Wei Liu
wiley   +1 more source

Thiamine and benfotiamine protect neuroblastoma cells against paraquat and β-amyloid toxicity by a coenzyme-independent mechanism

open access: yesHeliyon, 2019
Background: Benfotiamine (BFT) is a synthetic thiamine precursor with high bioavailability. It is efficient in treating complications of type 2 diabetes and has beneficial effects in mouse models of neurodegenerative diseases.
Margaux Sambon   +6 more
doaj  

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