Results 61 to 70 of about 104,500 (267)
Thiamine Metabolites and Dementia? [PDF]
The determinants of amyloid deposition in the brain, increased intracerebral phosphorylated tau, hippocampal atrophy, and loss of synapses in areas of brain (the pathogenic determinants of most dementia) remain undetermined except for Mendelian genetic disorders and higher risk of both amyloid deposition and dementia among individuals who carry the ...
openaire +4 more sources
Abstract Background Preterm infants are at risk of refeeding syndrome, a constellation of biochemical changes associated with nutrition. We aimed to determine whether increased early phosphate intake with routine biochemical monitoring is associated with a reduction in refeeding syndrome.
Thomas B. Wright+3 more
wiley +1 more source
PnuT uses a facilitated diffusion mechanism for thiamine uptake [PDF]
Membrane transporters of the bacterial pyridine nucleotide uptake (Pnu) family mediate the uptake of various B-type vitamins. For example, the PnuT transporters have specificity for vitamin B1 (thiamine).
Duurkens, Ria H+4 more
core +2 more sources
Abstract Refeeding syndrome (RS) is a potentially life‐threatening acute metabolic deterioration, affecting malnourished individuals. Although it is a well described condition, the evidence in pediatric population is limited. Herein, we describe a case of a 7‐year‐old patient with rumination syndrome and developmental delay, complicated with RS during ...
Olga Nikolaidou+6 more
wiley +1 more source
On the mechanism of the thiamine catalyzed reductive dimerization of farnesyl pyrophosphate to squalene. [PDF]
The mechanism of the dimerization of farnesyl pyrophosphate to squalene was investigated in detail. Thiamine was found to catalyze this dimerization in yeast-soluble enzyme preparations.
Durst, Horatio D.
core +2 more sources
Abstract Selenium (Se) is essential for human and animal health and nutritional status. As humans cannot produce Se, it must be obtained from the diet. Adequate Se supplementation improves innate immunity, increases antioxidant capacity and helps prevent various disorders.
Muna Ali Abdalla+2 more
wiley +1 more source
Potent Radical-Scavenging Activities of Thiamin and Thiamin Diphosphate
Various radical-scavenging activities of thiamin and thiamin diphosphate (TDP) were found in some in vitro experiments. Thiamin and TDP caused considerable suppressive effects on superoxide generation in hypoxanthine and xanthine oxidase system which was measured by a sensitive chemiluminescence method using 2-methyl-6-[p-methylphenyl]-3,7 ...
Yasuji Okai+4 more
openaire +4 more sources
Abstract Understanding dissolved concentrations of the essential coenzyme thiamin (vitamin B1) can provide insights into the biological controls on highly productive upwelling systems such as the California Current Ecosystem. To connect thiamin availability with microbial communities in the California Current Ecosystem, we measured concentrations of ...
Kelly C. Shannon+13 more
wiley +1 more source
Absorption of thiamine and nicotinic acid in the rat intestine during fasting and immobilization stress [PDF]
By perfusion of isolated sections of intestine with a solution containing thiamine at a concentration of 3.1 micromole, it was established that thiamine absorption in animals fasted for 72 hours decreased by 28 percent, whereas absorption increased by 12
Khmelevskiy, Y. V., Kirilyuk, O. G.
core +1 more source
Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]
Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk+9 more
core +1 more source