Results 51 to 60 of about 36,745 (354)

Re-emergence of thiamine deficiency disease in the Pacific islands (2014-15): A case-control study. [PDF]

PLoS ONE, 2018
BackgroundFrom late 2014 multiple atolls in Kiribati reported an unusual and sometimes fatal illness. We conducted an investigation to identify the etiology of the outbreak on the most severely affected atoll, Kuria, and identified thiamine deficiency ...
Eric J Nilles, Atarota Manaia, Bineta Ruaia, Clare Huppatz, Catherine Ward, Peter George, Christiaan Sies, Alessio Cangiano, James Sejvar, André Reiffer, Teatoa Tira   +10 more
doaj   +1 more source

Thiamine and benfotiamine: Focus on their therapeutic potential

Heliyon, 2023
Thiamine, also known as vitamin B1, is an essential nutrient that plays a crucial role in energy metabolism and overall health. It is a water-soluble vitamin that plays an important role in the conversion of carbohydrates into energy in the body ...
Iva Bozic, Irena Lavrnja
doaj   +1 more source

Spd2 assists Spd1 in modulation of RNR architecture but does not regulate deoxynucleotide pools [PDF]

, 2014
In yeasts, small intrinsically disordered proteins (IDPs) modulate ribonucleotide reductase (RNR) activity to ensure an optimal supply of dNTPs for DNA synthesis. The S. pombe Spd1 protein can directly inhibit the large RNR subunit (R1), import the small
Basrai, Beck, Bester, Bähler, Chabes, Danielsson, Elledge, Fairman, Fleck, Halazonetis, Hofer, Holmberg, Holmberg, Håkansson, Kjaerulff, Knutsen, Lee, Liu, Liu, Marguerat, Maundrell, Moreno, Moss, Nestoras, Nielsen, Nordlund, Reichard, Rhind, Salguero, Tompa, Uchiki, Weinberg, Woollard, Wu, Yoshida, Zhao, Zhao, Zolezzi   +37 more
core   +1 more source

Shoshin Beriberi Induced by Long-Term Administration of Diuretics: A Case Report

Case Reports in Cardiology, 2014
Previous studies have suggested that diuretic therapy for heart failure may lead to thiamine deficiency due to the increased urinary thiamine excretion.
Naoki Misumida, Hisashi Umeda, Mitsunori Iwase   +2 more
doaj   +1 more source

Case Report: Severe Edema and Marked Weight Gain Induced by Marginal Thiamine Deficiency in a Patient With Alcohol Dependency and Type 2 Diabetes Mellitus

Frontiers in Nutrition, 2021
Background: Patients with alcohol use disorder (AUD) may develop peripheral edema due to alcohol-related liver, renal, or heart disease. Thiamine deficiency is reported to occur in AUD and type 2 diabetes mellitus (T2DM).
Hitomi Tanaka, Takatoshi Anno, Haruka Takenouchi, Hideyuki Iwamoto, Hideaki Kaneto, Niro Okimoto, Koichi Tomoda   +6 more
doaj   +1 more source

Phenylboronic Acid‐Modified Copper Nanozymes as Nanoscavengers of Bacterial Polysaccharides Causing Acute Lung Injury

Advanced Science, EarlyView.
A novel copper nanocluster coated with 4‐mercaptobenzeneboronic acid (CuMPBA) is developed to target bacterial polysaccharides for addressing complicated acute lung injury (ALI) caused by severe burns and early pulmonary infections. CuMPBA exhibits dual anti‐inflammatory and antibacterial mechanisms by: (a) binding and degrading toxic bacterial ...
Haojie Ge, Min Wang, Haijiao Xie, Xu‐Lin Chen, Xianwen Wang   +4 more
wiley   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Thiamine-deficient optic neuropathy associated with Wernicke's encephalopathy in patients with chronic diarrhea

Journal of the Formosan Medical Association, 2013
The deficiency of thiamine manifesting as Wernicke's encephalopathy (WE) and concurrent optic neuropathy is rare. Herein, we report the case of a 29-year-old patient who suffered from bilateral sudden blindness and a disturbance of consciousness after 2 ...
Wei-Yi Yeh, Li-Ming Lian, Anna Chang, Cheng-Kuo Cheng   +3 more
doaj   +1 more source

Quality and Safety Aspects of Infant Nutrition [PDF]

, 2012
Quality and safety aspects of infant nutrition are of key importance for child health, but oftentimes they do not get much attention by health care professionals whose interest tends to focus on functional benefits of early nutrition.
Agostoni C, Agostoni C, Agostoni C, Aris B, Berthold Koletzko, Bier DM, Birlouez-Aragon I, Bonerba E, Cahill SM, Chang H, Dabeka R, Davanzo R, Day JB, Dewey KG, Domellof M, El-Tras WF, Erkekoglu P, Fattal-Valevski A, Fattal-Valevski A, Fattal-Valevski A, Fewtrell MS, Fewtrell MS, Flores JP, Friedman M, Gossner CM, Guzel A, Hamrin P, Hernell O, Hilbig A, Hirvonen T, Jongenburger I, Kaleita TA, Khlangwiset P, Kim SA, Koletzko B, Koletzko B, Koletzko B, Kornreich L, Kvist LJ, Lanska DJ, Lönnerdal B, Malloy MH, Margaret Ashwell, Miled RB, Mitkus RJ, Newberry RE, Norberg S, Oluwafemi F, Panfeng S, Pavesi Arisseto A, Raanan Shamir, Raecker T, Rebhan B, Reij MW, Ruiz E, Santillana MI, Schoder D, Shamir R, Silver LB, Simoneau C, Simoneau C, Snijder CA, Snijder CA, Szajewska H, Szajewska H, Turck D, Weistaub G, Welch RW, Whyatt RM, Willoughby A, Yen TH, Zlotkin S   +71 more
core   +1 more source

Biomanufacturing Potential of Streamlined Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT A series of Escherichia coli streamlined strains was developed by removing the expression of genes encoding extracellular structures and unessential enzymes. The streamlined strains exhibited improved metabolic performance, including lower overflow metabolism and ATP maintenance coefficient, as well as a higher growth rate, compared to their ...
Alvaro R. Lara, Marie B. Andersen, Alexander A. V. Madsen, Kathrine Gravlund Fønss, Marta Irla, Hilal Taymaz‐Nikerel, Luz María Martínez, Max Daniel Dicke, Marcel Mann, Jørgen B. Magnus, Guillermo Gosset   +10 more
wiley   +1 more source