Journal of Community Hospital Internal Medicine Perspectives, 2021 We describe a case of Wernicke’s encephalopathy secondary to thiamine (B1) deficiency in a patient status post-bariatric sleeve gastrectomy. The presenting symptoms of new-onset weakness, diplopia, and confusion in a young female patient raised suspicion
Divya Lal +2 more
doaj +1 more source
Feline vestibular disorders. Part II: diagnostic approach and differential diagnosis. [PDF]
, 1999 Results of a neurological examination usually permit localisation of a vestibular disorder to either the central or peripheral parts of the vestibular system. Many different disorders located in the same part of the vestibular system will produce similar
LeCouteur, RA, Vernau, KM
core
Chemistry &Biodiversity, EarlyView.This study presents a scalable strategy for producing Priestia megaterium α‐amylase (PmAmy) via fed‐batch fermentation, optimizing the biomass/IPTG ratio to enhance yield. With an activity of 67.7 U mL−1 at 22.3 g L−1 biomass, PmAmy demonstrated 99% efficiency in dough fermentation, highlighting its industrial potential as a sustainable baking enzyme .
Atacan Erdem +3 more
wiley +1 more source
Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application
Chemistry &Biodiversity, EarlyView.ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade +4 more
wiley +1 more source
ThiF‐Like Enzyme Chemistry in Primary and Secondary Metabolism
ChemBioChem, EarlyView.ThiF‐like enzymes are a widespread protein family found in disparate biosynthetic pathways. They are unified by their use of an NTP to modify a carboxylate, generating an activated species prone to nucleophilic addition. This common intermediate is then targeted by diverse nucleophiles, including persulfide or amino acid side chains, to yield a variety
Keelie S. Butler +2 more
wiley +1 more source
A novel encephalopathy in a thiamine-deficient dog resembling human Wernicke’s disease with atypical MRI pattern [PDF]
Open Veterinary Journal, 2017 Thiamine is a water-soluble vitamin, which participates in several vital metabolic pathways involved in energy metabolism and neurotransmitter synthesis of mammals.
Floriana Gernone, Mario Ricciardi
doaj +1 more source
Biochemical and haematological aspects of ethanol metabolism in humans : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University, New Zealand [PDF]
, 1983 Macrocytosis or raised mean cell volume (MCV) (which as measured by the Coulter S counter) is one of the results of alcohol abuse. There is a need to identify (chronic) alcoholics by laboratory tests.
Kwok, Hon Wing
core
Reaction Engineering of In Vitro Natural Product Biosynthesis: Challenges and Strategies
ChemBioChem, EarlyView.The yield and turnover of in vitro natural product biosynthesis, and even its feasibility, are determined by intermolecular interactions. Reaction engineering allows to improve the performance of such complex biocatalytic systems. Natural products are widely used as pharmaceuticals and agrochemicals, or as active ingredients in food and cosmetics ...
Elsa Sánchez‐García +2 more
wiley +1 more source
Shoshin Beriberi in a Child With Intestinal Failure: A Case Report
Critical Care ExplorationsBackground:. Acute illness states with increased metabolic demand can precipitate severe thiamine deficiency if physiologic needs exceed endogenous stores and supplementation.
Madeleine Böhrer, MD, FRCPC +4 more
doaj +1 more source
Aspects of the quantitative separation and estimation of thiamine and its phosphate esters : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]
, 1981 Methods for the separation and estimation of thiamine, thiamine monophosphate and thiamine diphosphate which would be applicable to biological extracts were investigated.
Scott, Paul Noel
core