Results 41 to 50 of about 13,523 (239)

Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism. [PDF]

open access: yes, 2019
Colonocytes possess a specific carrier-mediated uptake process for the microbiota-generated thiamin (vitamin B1) pyrophosphate (TPP) that involves the TPP transporter (TPPT; product of the SLC44A4 gene).
Anandam, Kasin Yadunandam   +4 more
core   +1 more source

High Lipid Content of Prey Fish and n3 PUFA Peroxidation Impair the Thiamine Status of Feeding-Migrating Atlantic Salmon (Salmo salar) and Is Reflected in Hepatic Biochemical Indices

open access: yesBiomolecules, 2022
Signs of impaired thiamine (vitamin B1) status in feeding-migrating Atlantic salmon (Salmo salar) were studied in three Baltic Sea areas, which differ in the proportion and nutritional composition of prey fish sprat (Sprattus sprattus) and herring ...
Marja Keinänen   +7 more
doaj   +1 more source

Protective Role of Thiamine Pyrophosphate Against Erlotinib-Induced Oxidative and Inflammatory Damage in Rat Optic Nerve. [PDF]

open access: goldBiomedicines
Karatas E   +7 more
europepmc   +2 more sources

Neurological, Psychiatric, and Biochemical Aspects of Thiamine Deficiency in Children and Adults. [PDF]

open access: yes, 2019
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are involved in energy metabolism and biosynthesis of nucleic acids whereas others ...
Adams   +154 more
core   +2 more sources

The Effect of Thiamine Concentration on the Antioxidative Activity Indices in Tea Extracts

open access: yesAntioxidants, 2019
The aim of the study was to determine correlations between the concentration of thiamine in systems and indicators of the antioxidative activity of ethanol tea extracts in the presence of soybean oil.
Justyna Piechocka   +4 more
doaj   +1 more source

Thermodynamic examination of the pyrophosphate sensor helix in the thiamine pyrophosphate riboswitch [PDF]

open access: yesRNA, 2011
Riboswitches are functional mRNA that control gene expression. Thiamine pyrophosphate (TPP) binds tothi-box riboswitch RNA and allosterically inhibits genes that code for proteins involved in the biosynthesis and transport of thiamine. Thiamine binding to the pyrimidine sensor helix and pyrophosphate binding to the pyrophosphate sensor helix cause ...
Stephanie, Furniss, Neena, Grover
openaire   +2 more sources

A Novel Mutation of SLC19A2 in a Chinese Zhuang Ethnic Family with Thiamine-Responsive Megaloblastic Anemia

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Thiamine-responsive megaloblastic anemia syndrome is a rare autosomal recessive disorder resulting from mutations in SLC19A2, and is mainly characterized by megaloblastic anemia, diabetes, and progressive sensorineural hearing loss ...
Xiaoying Xian   +7 more
doaj   +1 more source

The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels. [PDF]

open access: yesPLoS ONE, 2009
Vitamin B1 is in its active form thiamine pyrophosphate (TPP), an essential cofactor for several key enzymes in the carbohydrate metabolism. Mammals must salvage this crucial nutrient from their diet in order to complement the deficiency of de novo ...
Ingrid B Müller   +7 more
doaj   +1 more source

Toward eradication of B-vitamin deficiencies : considerations for crop biofortification [PDF]

open access: yes, 2018
'Hidden hunger' involves insufficient intake of micronutrients and is estimated to affect over two billion people on a global scale. Malnutrition of vitamins and minerals is known to cause an alarming number of casualties, even in the developed world ...
Strobbe, Simon   +1 more
core   +3 more sources

Perturbations in histidine biosynthesis uncover robustness in the metabolic network of Salmonella enterica. [PDF]

open access: yesPLoS ONE, 2012
Phosphoribosylamine (PRA) is an intermediate in the biosynthetic pathway that is common to thiamine and purines. Glutamine phosphoribosyl pyrophosphate (PRPP) amidotransferase is the product of the purF gene in Salmonella enterica and catalyzes the ...
Mark J Koenigsknecht   +3 more
doaj   +1 more source

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