Pathway of thiamine pyrophosphate synthesis in Micrococcus denitrificans [PDF]
Journal of Bacteriology, 1976 The pathway of thiamine pyrophosphate (TPP) biosynthesis, which is formed either from exogeneously added thiamine or from the pyrimidine and thiazole moieties of thiamine, in Micrococcus denitrificans was investigated. The following indirect evidence shows that thiamine pyrophosphokinase (EC 2.7.6.2) catalyzes the synthesis of TPP from thiamine: (i ...
H, Sanemori, Y, Egi, T, Kawasaki
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Inhibition of Intestinal Thiamin Transport in Rat Model of Sepsis. [PDF]
, 2016 ObjectivesThiamin deficiency is highly prevalent in patients with sepsis, but the mechanism by which sepsis induces thiamin deficiency is unknown. This study aimed to determine the influence of various severity of sepsis on carrier-mediated intestinal ...
Fang, Liwei +4 more
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Perturbations in histidine biosynthesis uncover robustness in the metabolic network of Salmonella enterica. [PDF]
PLoS ONE, 2012 Phosphoribosylamine (PRA) is an intermediate in the biosynthetic pathway that is common to thiamine and purines. Glutamine phosphoribosyl pyrophosphate (PRPP) amidotransferase is the product of the purF gene in Salmonella enterica and catalyzes the ...
Mark J Koenigsknecht +3 more
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Pathway Editing Targets for Thiamine Biofortification in Rice Grains
Frontiers in Plant Science, 2018 Thiamine deficiency is common in populations consuming polished rice as a major source of carbohydrates. Thiamine is required to synthesize thiamine pyrophosphate (TPP), an essential cofactor of enzymes of central metabolism. Its biosynthesis pathway has
Anu P. Minhas, Rakesh Tuli, Sanjeev Puri
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Biosynthetic Pathway of Thiamine Pyrophosphate: a Special Reference to the Thiamine Monophosphate-Requiring Mutant and the Thiamine Pyrophosphate-Requiring Mutant of Escherichia coli [PDF]
Journal of Bacteriology, 1972 Two types of mutants of Escherichia coli were isolated, one of which (mutant 70-23-107) responded to thiamine pyrophosphate, and the other (mutant 70-23-102) to thiamine monophosphate and thiamine pyrophosphate. They were produced by further mutation of a thiamine auxotroph of E.
H, Nakayama, R, Hayashi
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Critical Care, 2021 Background Thiamine is a precursor of the essential coenzyme thiamine pyrophosphate required for glucose metabolism; it improves the immune system function and has shown to reduce the risk of several diseases.
Khalid Al Sulaiman +14 more
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Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content. [PDF]
, 2018 A constellation of metabolic disorders, including obesity, dysregulated lipids, and elevations in blood glucose levels, has been associated with cardiovascular disease and diabetes. Analysis of data from recently published genome-wide association studies
Abad, Janna +14 more
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Bilateral ovarian ischemia/reperfusion injury and treatment options in rats with an induced model of diabetes [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective(s):This study investigated the effects of melatonin, famotidine, mirtazapine, and thiamine pyrophosphate on ischemia/reperfusion (I/R) injury in diabetic rats and evaluated oxidant and antioxidant marker measurement results.
Omer Erkan Yapca +4 more
doaj
, 2020 Aim: The aim of the study is to investigate the protective effect of thiamine pyrophosphate on methotrexateinduced gastrotoxicity biochemically in rats and to compare it with thiamine.
I. Cinar, Mine Gulapoglu, H. Suleyman
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A synthetic biochemistry platform for cell free production of monoterpenes from glucose. [PDF]
, 2017 Cell-free systems designed to perform complex chemical conversions of biomass to biofuels or commodity chemicals are emerging as promising alternatives to the metabolic engineering of living cells.
Bowie, James U +2 more
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