Results 71 to 80 of about 6,593 (171)
SUMMARY Alternative splicing (AS) is a common gene regulatory mechanism involving distinct interactions between trans‐acting factors and cis‐regulatory elements on the precursor messenger RNA (pre‐mRNA). In this study, we have functionally characterized the structured motif 45ABC, which is located in the pre‐mRNAs of RNA‐binding protein (RBP) 45 genes ...
Maren Reinhardt +5 more
wiley +1 more source
Sulfadiazine selection enables high‐efficiency transformation in Nannochloropsis and Microchloropsis
SUMMARY Nannochloropsis and Microchloropsis are important as eustigmatophyte model organisms and the production of high‐value lipids. Efficient selectable markers are indispensable for genetic engineering to study and improve production yield of these species.
Jannis Straube +3 more
wiley +1 more source
A whole‐cell biocatalytic cascade in engineered Escherichia coli RARE couples the ω‐transaminase from Pseudomonas psychrotolerans with pyruvate decarboxylase from Zymomonas mobilis to shift transamination toward amine formation via pyruvate removal. Integration of the cascade into a chemo‐enzymatic synthesis pathway enables the scalable production of 2,
Laura Edit Barabás +5 more
wiley +1 more source
The wide phenotypic spectrum of thiamine metabolism dysfunction syndrome 5 and its treatment
Thiamine metabolism dysfunction syndrome 5 (TMDS5) is a rare inborn error of metabolism caused by variants in TPK1, leading to reduced TPK levels. This enzyme is crucial for the production of thiamine pyrophosphate, the active form of thiamine, a vital ...
Alice Dallan +8 more
doaj +1 more source
Enzymic formation of thiamine pyrophosphate in plants.
Evidence was presented by paper chromatographic analysis on the occurrence of an enzyme capable of catalyzing a pyrophosphate transfer from ATP to thiamine in green leaves of various plants. The exclusive localization of the enzyme activity in the 105,000 X g supernatant (in a soluble form) was demonstrated by differential centrifugation of a cell ...
MITSUDA, Hisateru +3 more
openaire +3 more sources
Metabolism consists of biochemical reactions that are combined to generate a robust metabolic network that can respond to perturbations and also adapt to changing environmental conditions.
Jannell V. Bazurto +2 more
doaj +1 more source
Oxidative decarboxylation of retinoic acid in microsomes of rat liver and kidney
Liver and kidney microsomes have been found to catalyze a rapid decarboxylation of retinoic acid in vitro. The reaction requires NADPH and Fe2+, and is further stimulated by the presence of pyrophosphate.
Anita B. Roberts, Hector F. DeLuca
doaj +1 more source
Thiamine deficiency in alcoholics with normal body mass index
Background: Ethanol consumption leads to nutritional deficiency due to various causes. Well known theoretical as well as literature supports the hypothesis on dietary factors, metabolic derangement and alcohol per se produces empty calories.
Shanmugiah Arumugam
doaj +1 more source
Folding Kinetics of Riboswitch Transcriptional Terminators and Sequesterers
To function as gene regulatory elements in response to environmental signals, riboswitches must adopt specific secondary structures on appropriate time scales.
Ben Sauerwine, Michael Widom
doaj +1 more source
Debunking the myth: usage of thiamine in cervical preparation and labour augmentation
In Indonesia, thiamine (B1) has been use for cervical priming and enhancing uterine contraction in midwife and hospital setting as its off-label effect. However there are no clear evidence and research related to this issue.
A. Z. Suryawan +4 more
doaj +1 more source

