Results 71 to 80 of about 75,666 (233)

Thiamine Is Required for Virulence and Survival of Pseudomonas syringae pv. tomato DC3000 on Tomatoes

Frontiers in Microbiology, 2022
Pseudomonas syringae pv. tomato DC3000 (PstDC3000) is an important plant pathogen that infects tomatoes and Arabidopsis. Thiamine and its derivative thiamine pyrophosphate (TPP) are cofactors that play an important role in the growth and survival of many
Jun Liu, Jun Liu, Jun Liu, Xuejiang Zhang, Xuejiang Zhang, Xuejiang Zhang, Siyi Deng, Siyi Deng, Siyi Deng, Hua Wang, Hua Wang, Hua Wang, Youfu Zhao   +12 more
doaj   +1 more source

Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes [PDF]

, 2012
Increased renal clearance of thiamine (vitamin B1) occurs in experimental and clinical diabetes producing thiamine insufficiency mediated by impaired tubular re-uptake and linked to the development of diabetic nephropathy.
A Adaikalakoteswari, A AntonySunil, A Makino, A Turano, Anindita Das, AO Phillips, B Ashokkumar, B Dutta, B Sihag, BR Chamberlain, CME Tallaksen, Daniel Zehnder, ED Schleicher, Fang Zhang, G Gastaldi, GLJ Page, Guerman Molostvov, H Lum, H Smithline, HM Said, I Hubatsch, J Rieck, James R. Larkin, JC Reidling, JC Reidling, JC Reidling, JD Eudy, KA Robinson, Lisa Godfrey, MJ Boulware, MJ Ryan, MW Pfaffl, N Rabbani, N Rabbani, N Takahashi, N Tasevska, Naila Rabbani, Paul J. Thornalley, PJ Thornalley, R Babaei-Jadidi, S Sander, SM Nabokina, VS Subramanian   +42 more
core   +7 more sources

Synthesis of Mixed Dinucleotides by Mechanochemistry

Molecules, 2022
We report the synthesis of vitamin B1, B2, and B3 derived nucleotides and dinucleotides generated either through mechanochemical or solution phase chemistry.
Faisal Hayat, Mikhail V. Makarov, Luxene Belfleur, Marie E. Migaud   +3 more
doaj   +1 more source

Effect of thiamine pyrophosphate on retinopathy induced by hyperglycemia in rats: A biochemical and pathological evaluation.

Indian J Ophthalmol, 2016
Purpose: Information is lacking on the protective effects of thiamine pyrophosphate (TPP) against hyperglycemia-induced retinopathy in rats. This study investigated the biochemical and histopathological aspects of the effect of TPP on hyperglycemia ...
Cinici E, Ahiskali I, Cetin N, Suleyman B, Kukula O, Altuner D, Coban A, Balta H, Kuzucu M, Suleyman H.   +9 more
europepmc   +2 more sources

Scientific Opinion on the substantiation of a health claim related to thiamine and carbohydrate and energy‐yielding metabolism pursuant to Article 14 of Regulation (EC) No 1924/2006

EFSA Journal, 2010
Following an application from IDACE submitted pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an opinion on the scientific ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Solution structure of a bacterial microcompartment targeting peptide and its application in the construction of an ethanol bioreactor [PDF]

, 2014
Targeting of proteins to bacterial microcompartments (BMCs) is mediated by an 18-amino-acid peptide sequence. Herein, we report the solution structure of the N-terminal targeting peptide (P18) of PduP, the aldehyde dehydrogenase associated with the 1,2 ...
Brown, Ian R., Frank, Stefanie, Howard, Mark J., Lawrence, Andrew D., Lee, Matthew J., Mulvihill, Daniel P., Newnham, Sarah, Prentice, Michael B., Rowe, Michelle L., Warren, Martin J., Xue, Wei-Feng   +10 more
core   +1 more source

Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]

, 2015
Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk, Contestabile, Roberto, DI SALVO, Martino Luigi, Garik, Mkrtchyan, Lucien, Bettendorff, Parroni, Alessia, Thilo, Kaehne, Vasily, Aleshin, Victoria, Bunik, Yulia, Parkhomenko   +9 more
core   +1 more source

Studies on the Nature of the Binding of Thiamine Pyrophosphate to Enzymes

Journal of Biological Chemistry, 1968
Abstract The binding of thiamine pyrophosphate (TPP) to several enzymes has been determined by measuring cofactor-dependent activity after passage of each enzyme through a column of Sephadex G-25 to remove non-protein-bound cofactors. TPP was found to be bound irreversibly to yeast and Zymomonas pyruvate decarboxylases, Aerobacter α-acetolactate ...
A V, Morey, E, Juni
openaire   +2 more sources

Folding of the Thiamine Pyrophosphate (TPP) Riboswitch [PDF]

Biophysical Journal, 2010
TPP riboswitches regulate the expression of thiamine-synthesis (thi) genes through a variety of mechanisms, all of which involve binding of TPP to a structured aptamer formed in the untranslated region (UTR) of a thi mRNA. We used a high-resolution, single-molecule optical trapping assay to characterize mechanically the folding of the TPP riboswitch ...
Anthony, Peter C., Perez, Christian F., García-García, Cuauhtémoc, Block, Steven M.   +3 more
openaire   +1 more source

Experiments on the formation of carboxylase and thiamine pyrophosphate in living bakers' yeast [PDF]

, 1951
The formation of carboxylase by living bakers' yeast was demonstrated upon incubation of the yeast with either thiamine or 2-methyl-4-amino-5-ethoxymethylpyrimidine, in the presence and in the absence of glucose.
Leijnse, B., Terpstra, W.
core   +1 more source