Results 71 to 80 of about 6,590 (170)

Rewiring Carbon Metabolism in Bacillus methanolicus via Heterologous Phosphoketolase Expression Enhances Biomass Yield From Methanol and Reduces CO2 Loss

open access: yesMicrobial Biotechnology, Volume 19, Issue 9, September 2026.
Introducing a phosphoketolase pathway into Bacillus methanolicus enhances methanol‐to‐biomass yields by 18%–24% and reduces CO2 evolution by up to 12%. Coupled with a tunable expression system, this work demonstrates improved carbon conservation and expands metabolic engineering strategies for methylotrophs.
Yael J. Toporek   +6 more
wiley   +1 more source

The wide phenotypic spectrum of thiamine metabolism dysfunction syndrome 5 and its treatment

open access: yesOrphanet Journal of Rare Diseases
Thiamine metabolism dysfunction syndrome 5 (TMDS5) is a rare inborn error of metabolism caused by variants in TPK1, leading to reduced TPK levels. This enzyme is crucial for the production of thiamine pyrophosphate, the active form of thiamine, a vital ...
Alice Dallan   +8 more
doaj   +1 more source

Enzymic formation of thiamine pyrophosphate in plants.

open access: yesJournal of Nutritional Science and Vitaminology, 1975
Evidence was presented by paper chromatographic analysis on the occurrence of an enzyme capable of catalyzing a pyrophosphate transfer from ATP to thiamine in green leaves of various plants. The exclusive localization of the enzyme activity in the 105,000 X g supernatant (in a soluble form) was demonstrated by differential centrifugation of a cell ...
MITSUDA, Hisateru   +3 more
openaire   +3 more sources

An Unexpected Route to an Essential Cofactor: Escherichia coli Relies on Threonine for Thiamine Biosynthesis

open access: yesmBio, 2016
Metabolism consists of biochemical reactions that are combined to generate a robust metabolic network that can respond to perturbations and also adapt to changing environmental conditions.
Jannell V. Bazurto   +2 more
doaj   +1 more source

Oxidative decarboxylation of retinoic acid in microsomes of rat liver and kidney

open access: yesJournal of Lipid Research, 1968
Liver and kidney microsomes have been found to catalyze a rapid decarboxylation of retinoic acid in vitro. The reaction requires NADPH and Fe2+, and is further stimulated by the presence of pyrophosphate.
Anita B. Roberts, Hector F. DeLuca
doaj   +1 more source

Thiamine deficiency in alcoholics with normal body mass index

open access: yesJournal of Dr. NTR University of Health Sciences, 2019
Background: Ethanol consumption leads to nutritional deficiency due to various causes. Well known theoretical as well as literature supports the hypothesis on dietary factors, metabolic derangement and alcohol per se produces empty calories.
Shanmugiah Arumugam
doaj   +1 more source

Folding Kinetics of Riboswitch Transcriptional Terminators and Sequesterers

open access: yesEntropy, 2013
To function as gene regulatory elements in response to environmental signals, riboswitches must adopt specific secondary structures on appropriate time scales.
Ben Sauerwine, Michael Widom
doaj   +1 more source

Debunking the myth: usage of thiamine in cervical preparation and labour augmentation

open access: yesАкушерство, гинекология и репродукция
In Indonesia, thiamine (B1) has been use for cervical priming and enhancing uterine contraction in midwife and hospital setting as its off-label effect. However there are no clear evidence and research related to this issue.
A. Z. Suryawan   +4 more
doaj   +1 more source

Crystal structure of Escherichia coli thiamine pyrophosphate-sensing riboswitch in the apo state. [PDF]

open access: yesStructure, 2023
Lee HK   +10 more
europepmc   +1 more source

Enhancement of the therapeutic efficacy of the MAP regimen using thiamine pyrophosphate-decorated albumin nanoclusters in osteosarcoma treatment. [PDF]

open access: yesBioeng Transl Med, 2023
Yoo SY   +18 more
europepmc   +1 more source

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