Results 51 to 60 of about 13,523 (239)

Biosynthesis of Thiamine Pyrophosphate in Escherichia coli [PDF]

open access: yesJournal of Bacteriology, 1972
In Escherichia coli , thiamine pyrophosphate is synthesized from thiamine monophosphate. Free thiamine is not involved as an intermediate in de novo synthesis of thiamine pyrophosphate.
H, Nakayama, R, Hayashi
openaire   +2 more sources

Pathway Editing Targets for Thiamine Biofortification in Rice Grains

open access: yesFrontiers in Plant Science, 2018
Thiamine deficiency is common in populations consuming polished rice as a major source of carbohydrates. Thiamine is required to synthesize thiamine pyrophosphate (TPP), an essential cofactor of enzymes of central metabolism. Its biosynthesis pathway has
Anu P. Minhas, Rakesh Tuli, Sanjeev Puri
doaj   +1 more source

Evaluation of thiamine as adjunctive therapy in COVID-19 critically ill patients: a two-center propensity score matched study

open access: yesCritical Care, 2021
Background Thiamine is a precursor of the essential coenzyme thiamine pyrophosphate required for glucose metabolism; it improves the immune system function and has shown to reduce the risk of several diseases.
Khalid Al Sulaiman   +14 more
doaj   +1 more source

Inhibition of Intestinal Thiamin Transport in Rat Model of Sepsis. [PDF]

open access: yes, 2016
ObjectivesThiamin deficiency is highly prevalent in patients with sepsis, but the mechanism by which sepsis induces thiamin deficiency is unknown. This study aimed to determine the influence of various severity of sepsis on carrier-mediated intestinal ...
Fang, Liwei   +4 more
core   +2 more sources

Pathway of thiamine pyrophosphate synthesis in Micrococcus denitrificans [PDF]

open access: yesJournal of Bacteriology, 1976
The pathway of thiamine pyrophosphate (TPP) biosynthesis, which is formed either from exogeneously added thiamine or from the pyrimidine and thiazole moieties of thiamine, in Micrococcus denitrificans was investigated. The following indirect evidence shows that thiamine pyrophosphokinase (EC 2.7.6.2) catalyzes the synthesis of TPP from thiamine: (i ...
H, Sanemori, Y, Egi, T, Kawasaki
openaire   +2 more sources

Bilateral ovarian ischemia/reperfusion injury and treatment options in rats with an induced model of diabetes [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2014
Objective(s):This study investigated the effects of melatonin, famotidine, mirtazapine, and thiamine pyrophosphate on ischemia/reperfusion (I/R) injury in diabetic rats and evaluated oxidant and antioxidant marker measurement results.
Omer Erkan Yapca   +4 more
doaj  

Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content. [PDF]

open access: yes, 2018
A constellation of metabolic disorders, including obesity, dysregulated lipids, and elevations in blood glucose levels, has been associated with cardiovascular disease and diabetes. Analysis of data from recently published genome-wide association studies
Abad, Janna   +14 more
core   +3 more sources

Displacement of thiamine pyrophosphate from swollen mitochondria

open access: yesBiochimica et Biophysica Acta, 1957
The distribution of TPP in cytoplasm fractions of rat liver is studied. When the homogenate was prepared with 0.25M sucrose, about 300% of TPP was present in mitochondria. When the homogenization medium was distilled water, the amount of TPP present in this fraction was markedly decreased, while that present in the supernatant fluid was increased ...
Dianzani, M.U., Dianzani Mor, M.A.
openaire   +3 more sources

Thiamine Is Required for Virulence and Survival of Pseudomonas syringae pv. tomato DC3000 on Tomatoes

open access: yesFrontiers in Microbiology, 2022
Pseudomonas syringae pv. tomato DC3000 (PstDC3000) is an important plant pathogen that infects tomatoes and Arabidopsis. Thiamine and its derivative thiamine pyrophosphate (TPP) are cofactors that play an important role in the growth and survival of many
Jun Liu   +12 more
doaj   +1 more source

Synthesis of Mixed Dinucleotides by Mechanochemistry

open access: yesMolecules, 2022
We report the synthesis of vitamin B1, B2, and B3 derived nucleotides and dinucleotides generated either through mechanochemical or solution phase chemistry.
Faisal Hayat   +3 more
doaj   +1 more source

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