Results 111 to 120 of about 7,524 (233)
Type 2 Diabetes and Thiazide Diuretics.
peer reviewedPURPOSE OF REVIEW: In patients with prediabetes or type 2 diabetes, the use of thiazides as antihypertensive agents has been challenged because associated metabolic adverse events, including new-onset diabetes.
Scheen, André, André J. Scheen
core +1 more source
Purpose Hypertension is associated with dyslipidemia. Thiazides adversely affect serum lipid levels in hypertensives. There is currently a dearth of information on benefits of aerobic exercise training on serum lipid levels in individuals on thiazides ...
YILDIRIM, SEVİL +3 more
core +1 more source
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Takaya Uno +10 more
wiley +1 more source
Effects of three years of low-dose thiazides on mineral metabolism in healthy elderly persons
UnlabelledIn this clinical trial of 12.5 or 25 mg/day of hydrochlorothiazide, the urine calcium showed significant decreases from placebo in men at one year, but the effects had waned by 3 years. Serum bicarbonate was consistently greater in the thiazide
Wu, K +4 more
core +1 more source
Evaluating the Educational Value of Artificial Intelligence in Pharmacotherapy Education
ABSTRACT Final‐year medical students frequently make prescribing errors, partly because they have had insufficient training in therapeutic reasoning. Students need to understand the underlying rationale behind a drug choice in order to subsequently apply that knowledge critically and independently.
Mariëlle G. Hartjes +4 more
wiley +1 more source
Little is known about the residues that control the binding and affinity of thiazide-type diuretics for their protein target, the renal Na+-Cl−cotransporter (NCC).
María Castañeda-Bueno +9 more
core +1 more source
Abstract Study objectives To investigate the use of automated analysis to detect heart rate accelerations (HRAs) to screen for sleep‐disordered breathing (SDB) among patients who use chronotropic medications. Methods Nocturnal polysomnography (NPSG) recordings from 933 participants in the Sleep Heart Health Study were analyzed using an automated method
Nabila Ahmed +11 more
wiley +1 more source
Printed educational messages fail to increase use of thiazides as first-line medication for hypertension in primary care: a cluster randomized controlled trial [ISRCTN72772651] [PDF]
Background: Evidence on the effectiveness of printed educational messages in contributing to increasing evidence-based clinical practice is contradictory.
Croxford R +15 more
core
Introduction: Both dietary restriction of sodium chloride (NaCl) and treatment with thiazides have been used in hypercalciuric patients. Objectives: To calculate regular salt intake and investigate the correlation between natriuresis and urinary calcium ...
Albero Gamboa, R. +13 more
core +1 more source
Obstructive sleep apnoea is associated with accelerated progression of diabetic kidney disease
Abstract Aim Persons with type 2 diabetes and diabetic kidney disease (DKD) are at high risk of end‐stage kidney disease or death. We investigated the possible contribution of obstructive sleep apnoea (OSA) to decline in kidney function and renal outcomes.
Sebastian Nielsen +9 more
wiley +1 more source

