Results 111 to 120 of about 7,524 (233)

Type 2 Diabetes and Thiazide Diuretics.

open access: yes, 2018
peer reviewedPURPOSE OF REVIEW: In patients with prediabetes or type 2 diabetes, the use of thiazides as antihypertensive agents has been challenged because associated metabolic adverse events, including new-onset diabetes.
Scheen, André, André J. Scheen
core   +1 more source

Aerobic Dance or Step Dance Which Exercise Can Increase Balance Flexibility and Muscle Strength of University Students

open access: yes, 2014
Purpose Hypertension is associated with dyslipidemia. Thiazides adversely affect serum lipid levels in hypertensives. There is currently a dearth of information on benefits of aerobic exercise training on serum lipid levels in individuals on thiazides ...
YILDIRIM, SEVİL   +3 more
core   +1 more source

Intravenous Tolvaptan Sodium Phosphate Can Fail to Improve Fluid Overload Due to Heart Failure in Patients With Chronic Kidney Disease: A Case Report

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Takaya Uno   +10 more
wiley   +1 more source

Effects of three years of low-dose thiazides on mineral metabolism in healthy elderly persons

open access: yes, 2008
UnlabelledIn this clinical trial of 12.5 or 25 mg/day of hydrochlorothiazide, the urine calcium showed significant decreases from placebo in men at one year, but the effects had waned by 3 years. Serum bicarbonate was consistently greater in the thiazide
Wu, K   +4 more
core   +1 more source

Evaluating the Educational Value of Artificial Intelligence in Pharmacotherapy Education

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Final‐year medical students frequently make prescribing errors, partly because they have had insufficient training in therapeutic reasoning. Students need to understand the underlying rationale behind a drug choice in order to subsequently apply that knowledge critically and independently.
Mariëlle G. Hartjes   +4 more
wiley   +1 more source

A single residue in transmembrane domain 11 defines the different affinity for thiazides between the mammalian and flounder NaCl transporters

open access: yes, 2010
Little is known about the residues that control the binding and affinity of thiazide-type diuretics for their protein target, the renal Na+-Cl−cotransporter (NCC).
María Castañeda-Bueno   +9 more
core   +1 more source

Role of novel automated methods in pulse signal analysis to screen for sleep‐disordered breathing among patients on chronotropic medications

open access: yesSleep Research, Volume 3, Issue 2, Page 98-107, June 2026.
Abstract Study objectives To investigate the use of automated analysis to detect heart rate accelerations (HRAs) to screen for sleep‐disordered breathing (SDB) among patients who use chronotropic medications. Methods Nocturnal polysomnography (NPSG) recordings from 933 participants in the Sleep Heart Health Study were analyzed using an automated method
Nabila Ahmed   +11 more
wiley   +1 more source

Printed educational messages fail to increase use of thiazides as first-line medication for hypertension in primary care: a cluster randomized controlled trial [ISRCTN72772651] [PDF]

open access: yes
Background: Evidence on the effectiveness of printed educational messages in contributing to increasing evidence-based clinical practice is contradictory.
Croxford R   +15 more
core  

A comparison of effects induced on urinary calcium by thiazides and different doses of salt in the diet: Implications in clinical practice

open access: yes, 2019
Introduction: Both dietary restriction of sodium chloride (NaCl) and treatment with thiazides have been used in hypercalciuric patients. Objectives: To calculate regular salt intake and investigate the correlation between natriuresis and urinary calcium ...
Albero Gamboa, R.   +13 more
core   +1 more source

Obstructive sleep apnoea is associated with accelerated progression of diabetic kidney disease

open access: yesDiabetic Medicine, Volume 43, Issue 6, June 2026.
Abstract Aim Persons with type 2 diabetes and diabetic kidney disease (DKD) are at high risk of end‐stage kidney disease or death. We investigated the possible contribution of obstructive sleep apnoea (OSA) to decline in kidney function and renal outcomes.
Sebastian Nielsen   +9 more
wiley   +1 more source

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