Results 21 to 30 of about 7,524 (233)

Fixed combination of bisoprolol and a low-dose hydrochlorothiazide in arterial hypertension [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2018
Beta-blockers showed better results in lowering elevated blood pressure in the younger age group of patients with higher renin plasma levels. Actual recommendations from the European Society of Cardiology for treatment of arterial hypertension from 2013 ...
Ivanović Branislava   +3 more
doaj   +1 more source

Drug‐induced vasculitis: Thiazide or the COVID‐19 vaccine, which one is guilty? A case report and literature review

open access: yesClinical Case Reports, 2022
A middle‐aged woman with a history of COVID‐19 vaccine administration and valve replacement surgery was admitted with bilateral palpable purpuric lesions in the lower extremities and headache.
Manoochehr Hekmat   +3 more
doaj   +1 more source

Presentation, diagnostic assessment and surgical outcomes in primary hyperparathyroidism: a single centre’s experience

open access: yesEndocrine Connections, 2018
Objective: Primary hyperparathyroidism (PHPT) is a common reason for referral to endocrinology but the evidence base guiding assessment is limited. We evaluated the clinical presentation, assessment and subsequent management in PHPT.
Laura J Reid   +7 more
doaj   +1 more source

Thiazides attenuate insulin secretion through inhibition of mitochondrial carbonic anhydrase 5b in β-islet cells in mice

open access: yes, 2023
Background: Thiazides are associated with glucose intolerance and new onset diabetes mellitus. Previous studies demonstrated that thiazides attenuate insulin secretion, but the molecular mechanisms remain elusive. We hypothesized that thiazides attenuate
Daniel, Fuster
core   +1 more source

Thiazide-Induced Hyponatremia [PDF]

open access: yesElectrolytes & Blood Pressure, 2010
The importance of thiazide-induced hyponatremia (TIH) is reemerging because thiazide diuretic prescription seems to be increasing after the guidelines recommending thiazides as first-line treatment of essential hypertension have been introduced. Thiazide diuretics act by inhibiting reabsorption of Na(+) and Cl(-) from the distal convoluted tubule by ...
Hwang, Kyu Sig, Kim, Gheun-Ho
openaire   +2 more sources

Thiazide Diuretics and Fracture Risk: A Systematic Review and Meta‐Analysis of Randomized Clinical Trials

open access: yesJBMR Plus, 2022
Thiazide diuretics are commonly used antihypertensive agents. Until today, whether their use reduces fracture risk remains unclear. Our objective was to conduct a systematic review of thiazide diuretics’ effects on fractures and bone mineral density (BMD)
Louis‐Charles Desbiens   +6 more
doaj   +1 more source

The pharmacodynamic effects of thiazides from a computational physiological perspective [PDF]

open access: yes, 2017
Background. Primary hypertension is the leading risk factor for mortality in low-, middle- and high-income countries and affects more than one billion people world-wide.
Kiær, Håkon   +1 more
core   +1 more source

Back to thiazide-diuretics for hypertension: reflections after a decade of irrational prescribing

open access: yesBMC Family Practice, 2003
Background Whether newer antihypertensive drugs, such as calcium channel blockers, angiotensin converting enzyme inhibitors and α blockers are more effective than thiazides and β blockers in preventing coronary disease, has been debated for years ...
Fretheim Atle
doaj   +1 more source

Risk of Developing Hypokalemia in Patients With Hypertension Treated With Combination Antihypertensive Therapy [PDF]

open access: yes, 2020
Little is known about the occurrence of hypokalemia due to combination therapy for hypertension. Using data from Danish administrative registries, we investigated the association between different combinations of antihypertensive therapy and risk of ...
Rikke Nørmark Mortensen   +17 more
core   +1 more source

Long-term comparative effectiveness of antihypertensive monotherapies in primary prevention of cardiovascular events: a population-based retrospective inception cohort study in the Netherlands

open access: yesBMJ Open, 2023
Objective To determine the long-term effectiveness of antihypertensive monotherapies in primary prevention of cardiovascular events.Design Retrospective inception cohort study covering a 25-year study period.Setting University Groningen IADB.nl pharmacy ...
Xuechun Li   +4 more
doaj   +1 more source

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