Results 31 to 40 of about 11,021 (223)
BMJ Open, 2023 Objective To determine the long-term effectiveness of antihypertensive monotherapies in primary prevention of cardiovascular events.Design Retrospective inception cohort study covering a 25-year study period.Setting University Groningen IADB.nl pharmacy ...
Xuechun Li +4 more
doaj +1 more source
JID InnovationsSome antihypertensive medications are photosensitizing. The implications for skin cancer risk remain unclear because results from prior studies are inconsistent and as new evidence is published.
Olivia G. Cohen +8 more
doaj +1 more source
Management of hypertension in children and adolescents [PDF]
, 2014 Hypertension has been recognized as an important health issue in the pediatric population over the past years. This emphasizes the need for an organized and effective plan for diagnosis and management. This review provides information to guide physicians
De Bruyne, Pauline, Vande Walle, Johan
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Kidney and Blood Pressure Research, 1987 Thiazide diuretics increase salt and water excretion primarily by inhibiting mechanisms for electroneutral sodium and chloride transport by distal convoluted tubule cells. This might be termed the ‘specific’ effect of this class of diuretics and accounts for the ‘chlorouretic’ effectiveness of the drug.
openaire +2 more sources
NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity. [PDF]
PLoS ONE, 2017 Animal studies have shown that the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus can activate the thiazide-sensitive NaCl cotransporter (NCC). A common side effect of CNIs is hypertension.
Omar A Z Tutakhel +11 more
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[Translated article] What Dermatologists Should Know About Thiazides
Actas Dermo-Sifiliográficas, 2022 Hydrochlorothiazide and other thiazide diuretics have been used for decades to treat high blood pressure, heart failure, and chronic kidney disease. Thiazides have been linked to photosensitivity with heterogeneous clinical manifestations and recovery ...
J.M. Llamas-Molina +2 more
doaj +1 more source
Patterns of antihypertensive prescribing, discontinuation and switching among a Hong Kong Chinese population from over one million prescriptions [PDF]
, 2008 Hypertension is an alarming public health problem among Chinese. The present study evaluated the prescribing patterns, discontinuation and switching profiles of antihypertensive agents and their associated factors in one Hong Kong Chinese population ...
A Fretheim +14 more
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Clinical and molecular features of thiazide-induced hyponatremia [PDF]
, 2018 Hypertension affects more than 30% of the world’s adult population and thiazide (and thiazide-like) diuretics are amongst the most widely used, effective and least costly treatments available, with all-cause mortality benefits equivalent to ACE ...
Channavajjhala, Sarath K. +5 more
core +2 more sources
Printed educational messages fail to increase use of thiazides as first-line medication for hypertension in primary care: a cluster randomized controlled trial [ISRCTN72772651] [PDF]
, 2015 BACKGROUND: Evidence on the effectiveness of printed educational messages in contributing to increasing evidence-based clinical practice is contradictory.
Austin, P. C. +15 more
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The Journal of Clinical HypertensionPrevious work comparing safety and effectiveness outcomes for new initiators of angiotensin converting‐enzyme inhibitors (ACEi) and thiazides demonstrated more favorable outcomes for thiazides, although cohort definitions allowed for addition of a second
Tara V. Anand +4 more
doaj +1 more source