Results 31 to 40 of about 7,524 (233)

Palatability of crushed ß-blockers, converting enzyme inhibitors and thiazides

, 2012
WHAT IS KNOWN AND OBJECTIVES: A problem that often affects antihypertensive drugs is the lack of formulations appropriate for childhood. Parents, therefore, crush tablets and administer the antihypertensive drug mixed with solid food or a palatable drink.
Fossali, E F, Lava, S A G, Zgraggen, L, Simonetti, G D, Amoruso, C, Bianchetti, M G, Faré, P B   +6 more
core   +1 more source

NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity. [PDF]

PLoS ONE, 2017
Animal studies have shown that the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus can activate the thiazide-sensitive NaCl cotransporter (NCC). A common side effect of CNIs is hypertension.
Omar A Z Tutakhel, Arthur D Moes, Marco A Valdez-Flores, Marleen L A Kortenoeven, Mathijs V D Vrie, Sabina Jeleń, Robert A Fenton, Robert Zietse, Joost G J Hoenderop, Ewout J Hoorn, Luuk Hilbrands, René J M Bindels   +11 more
doaj   +1 more source

[Translated article] What Dermatologists Should Know About Thiazides

Actas Dermo-Sifiliográficas, 2022
Hydrochlorothiazide and other thiazide diuretics have been used for decades to treat high blood pressure, heart failure, and chronic kidney disease. Thiazides have been linked to photosensitivity with heterogeneous clinical manifestations and recovery ...
J.M. Llamas-Molina, F.J. Navarro-Triviño, R. Ruiz-Villaverde   +2 more
doaj   +1 more source

Thiazide and Thiazide-Like Diuretics [PDF]

Hypertension, 2012
See related article, pp 1104–1109 Peterzan et al1 have provided an important new meta-analysis of the dose-response relationships for 2 different thiazide diuretics and 1 thiazide-like diuretic. The focus was on antihypertensive efficacy, with brief reference to alterations in serum electrolyte measures.
Matthew R, Weir, Rajiv, Agarwal
openaire   +2 more sources

Thiazide Diuretics

Kidney and Blood Pressure Research, 1987
Thiazide diuretics increase salt and water excretion primarily by inhibiting mechanisms for electroneutral sodium and chloride transport by distal convoluted tubule cells. This might be termed the ‘specific’ effect of this class of diuretics and accounts for the ‘chlorouretic’ effectiveness of the drug.
openaire   +2 more sources

Printed educational messages fail to increase use of thiazides as first-line medication for hypertension in primary care: a cluster randomized controlled trial [ISRCTN72772651] [PDF]

, 2015
Background Evidence on the effectiveness of printed educational messages in contributing to increasing evidence-based clinical practice is contradictory.
Tu, K., Godin, Gaston, Austin, P. C., Hux, JE, Grimshaw, J. M., Paterson, J. M., Shiller, S., Zwarenstein, M., Eccles, MP, Hux, J. E., Eccles, Martin P, Tetroe, J, Eccles, M. P., Francis, J., Hux, Janet E, Austin, PC, Kelsall, Diane, Francis, JJ, Tu, K, Grimshaw, JM, Tetroe, J., Presseau, Justin, Kelsall, D, Paterson, J. M, Kelsall, D., Zwarenstein, M, Austin, Peter C, Tetroe, Jacqueline, Godin, G, Francis, Jill J, Paterson, J Michael, Yun, L., Yun, Lingsong, Johnston, M, Yun, L, Presseau, J, Godin, G., Johnston, M., Croxford, R., Paterson, JM, Tu, Karen, Croxford, R, Shiller, SK, Grimshaw, Jeremy M, Shiller, Susan K, Johnston, Marie, Presseau, J., Zwarenstein, Merrick, Croxford, Ruth   +48 more
core   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Thiazide and Thiazide-Like Diuretics in Therapy of Arterial Hypertension

Kardiologiia, 2019
The review presents results of clinical studies of efficacy and safety of thiazide and thiazide-like diuretics in the treatment of patients with arterial hypertension. In this work we have compared the role of diuretics in modern clinical recommendation on control of arterial pressure, and assessed in comparative aspect metabolic effects of thiazide ...
Ya A, Orlova, N V, Kurlykina, E M, Seredenina   +2 more
openaire   +3 more sources

Prevention of calcium stones with thiazides

, 1978
In 1962, we began a clinical trial designed to assess the efficacy of the thiazide diuretics in the prevention of calcific urinary calculi. During the subsequent 15 years, we have initiated thiazide therapy in 346 patients.
Cohanim, Moussa, Yendt, Edmund R.
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source