Results 51 to 60 of about 7,524 (233)

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad   +9 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

The potential savings of using thiazides as the first choice antihypertensive drug: cost-minimisation analysis

open access: yesBMC Health Services Research, 2003
Background All clinical practice guidelines recommend thiazides as a first-choice drug for the management of uncomplicated hypertension. Thiazides are also the lowest priced antihypertensive drugs.
Oxman Andrew D   +2 more
doaj  

Resource management and clinical outcomes during a national intravenous fluid shortage

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background A natural disaster, Hurricane Helene, damaged a production facility supplying 60% of intravenous (IV) fluids in the United States. A nationwide IV fluid shortage followed. Objectives To evaluate a multifaceted IV fluid conservation intervention's effect on IV fluid utilization and clinical outcomes during the shortage.
Stacy A. Johnson   +3 more
wiley   +1 more source

Propofol‐induced hypertriglyceridemia in critically ill trauma patients requiring nutrition therapy: A descriptive cohort study

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background This study aimed to assess the incidence and identify risk factors associated with the development of propofol‐induced hypertriglyceridemia in critically ill trauma patients who required nutrition therapy. Methods Adult patients (aged >17 years) admitted to the trauma intensive care unit who received propofol for >24 h and had a ...
Emma S. Lemke   +5 more
wiley   +1 more source

Thiazides stimulate calcium absorption in the turtle bladder

open access: yes, 1988
Thiazides stimulate calcium absorption in the turtle bladder. The mechanism of action of the thiazide diuretics on calcium transport is not completely understood.
Sabatini, Sandra, Kurtzman, Neil A.
core   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Diuretics: a review of the pharmacology and effects on glucose homeostasis

open access: yesFrontiers in Pharmacology
Thiazides, thiazide-like and loop diuretics are commonly prescribed to manage hypertension and heart failure. The main mechanism of action of these diuretics involve inhibition of Na+ reabsorption in the kidneys, leading to increased urine production ...
Mauricio Di Fulvio   +2 more
doaj   +1 more source

Secular Trend in Glycaemic Management in Type 2 Diabetes Patients With and Without Cirrhosis Between 2000 and 2023: A Territory‐Wide Cohort Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this territory‐wide cohort study, improving glycemic control can be observed regardless of cirrhosis status. Oral antidiabetic medication was more often used in the non‐cirrhosis group, and insulin was preferred in patients with decompensated cirrhosis, who exhibited an increasing incidence of hypoglycemia over the years and need individualized ...
Mary Yue Wang   +6 more
wiley   +1 more source

Diuretics and Hypokalemia [PDF]

open access: yesActa Medica Iranica, 1970
We have studied hypokalemic action of different diuretics in a cooperative study on 28 patients and our results are as follows: I. 28 patients (18 male and 10 female) were the subject of our present study. 2. E. C. G.
Ali A. Handjani   +2 more
doaj   +2 more sources

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