Results 71 to 80 of about 7,524 (233)

Factors of importance for discontinuation of thiazides associated with hyponatremia in Sweden: A population‐based register study

, 2019
PURPOSE: In a patient with clinically significant hyponatremia without other clear causes, thiazide treatment should be replaced with another drug. Data describing to which extent this is being done are scarce.
Cecilia Fahlén Bergh, Jan Calissendorff, Johnell, Kristina,, Kristina Johnell, Skov, Jakob,, Calissendorff, Jan,, Jakob Skov, Susanna Toivanen, David Nathanson, Lindh, Jonatan D,, Mannheimer, Buster,, Toivanen, Susanna,, Buster Mannheimer, Fahlén Bergh, Cecilia,, Henrik Falhammar, Jonatan D. Lindh, Falhammar, Henrik,, Nathanson, David,   +17 more
core   +1 more source

Amiodarone‐related thyroid dysfunction and associated outcomes in patients with heart failure—A nationwide cohort study

Journal of Internal Medicine, EarlyView.
Abstract Aim Amiodarone increases the risk of thyroid dysfunction, but the prognostic significance of this complication in patients with heart failure (HF) is uncertain. This study investigates the association between amiodarone‐related thyroid dysfunction and risk of HF hospitalization or death in a nationwide cohort.
Søren Lund Kristensen, Sam Aiyad Ali, Mads Ersbøll, Jawad Haider Butt, Rasmus Rørth, Lucas Malta Westergaard, Lauge Østergaard, Finn Gustafsson, Oren Caspi, Emil Fosbøl, Lars Køber, Christian Selmer   +11 more
wiley   +1 more source

Thiazides as a Monotherapy/Combination Therapy in Management of Essential Hypertension

, 2021
Background: Essential hypertension is a chronic disease that can lead to stroke or death if uncontrolled. It is both a global problem in the U.S. and the world.
Onuchukwu-Azuonye, Chinonye
core  

Target Trial Emulation in Observational Research—Strengths, Limitations, and Methodological Considerations

Journal of Periodontal Research, EarlyView.
The target trial framework is a pragmatic roadmap for observational causal inference that clarifies questions, mitigates time‐related bias, and improves interpretability while acknowledging limits. With transparent protocols, appropriate methods, and suitable data, it can complement randomized trials and inform practice and policy.
Sebastian‐Edgar Baumeister, Ignacio Leiva‐Escobar, Ryan T. Demmer, Panos N. Papapanou, Thomas Kocher, Birte Holtfreter, Michael Nolde   +6 more
wiley   +1 more source

Emerging risk factors influencing the occurrence of peri‐implantitis

Periodontology 2000, EarlyView.
Abstract Background The objective of the present review is to explore the evidence and biological plausibility of factors that may expose dental implants to a greater likelihood of developing peri‐implantitis. Material and Methods An electronic screening on the PubMed library the was carried out to identify potential emerging factors that influence the
Alberto Monje, Ronald E. Jung, Cristina Valles, Nadja Naenni   +3 more
wiley   +1 more source

Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers.

PLoS ONE, 2019
BackgroundHypertension (HTN) disproportionately affects African Americans (AAs), who respond better to thiazide diuretics than other antihypertensives. Variants of the APOL1 gene found in AAs are associated with a higher rate of kidney disease and play a
Patrick N Cunningham, Zhiying Wang, Megan L Grove, Rhonda M Cooper-DeHoff, Amber L Beitelshees, Yan Gong, John G Gums, Julie A Johnson, Stephen T Turner, Eric Boerwinkle, Arlene B Chapman   +10 more
doaj   +1 more source

Detection of renal tubular transporter proteins in canine urinary extracellular vesicles using liquid chromatography–tandem mass spectrometry

Veterinary Clinical Pathology, EarlyView.
Abstract Urinary extracellular vesicles (UEVs) are membranous particles that carry renal tubular transporter proteins. Here, we evaluate whether selected renal tubular transporter proteins can be detected in UEVs isolated from small volume (1–5 mL) canine urine samples of healthy dogs and canine patients with elevated circulating parathyroid hormone ...
L. J. McGravey, P. R. Antrobus, T. L. Williams   +2 more
wiley   +1 more source

Coadministration of thiazides increases the efficacy of loop diuretics even in patients with advanced renal failure

, 1994
Coadministration of thiazides increases the efficacy of loop diuretics even in patients with advanced renal failure. It is commonly assumed that thiazide diuretics are ineffective in patients with advanced renal failure (GFR < 30 ml/min/1.73 m2 ...
Ritz, Eberhard, Schröter, Markus, Neubeck, Monika, Fliser, Danilo   +3 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Ablation of the Cl-/HCO3- Exchanger Pendrin Enhances Hydrochlorothiazide-Induced Diuresis

Kidney & Blood Pressure Research, 2017
Background/Aims: The Cl-/HCO3- exchanger pendrin and the thiazide-sensitive Na-Cl cotransporter NCC are expressed in the kidney distal nephron and mediate salt absorption.
Saeed Alshahrani, Manoocher Soleimani
doaj   +1 more source