Results 81 to 90 of about 7,524 (233)

Glucagon‐Like Peptide‐1 Agonist vs. Placebo and Pulmonary Decline After Open‐Heart Surgery: A Substudy of the GLORIOUS Randomised Clinical Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Postoperative pulmonary decline is an established complication of open‐heart surgery extending beyond the immediate postoperative phase. Inflammation‐mediated lung damage and ischaemia‐reperfusion injury secondary to extracorporeal circulation is a proposed pathophysiological driver. GLP‐1 receptor agonists (GLP‐1RA) have emerged as
Astrid Duus Mikkelsen, Sebastian Wiberg, Hans Henrik Lawaetz Schultz, Peter Hasse Møller‐Sørensen, Dan Høfsten, Jens Christian Nilsson, Christian Holdflod Møller, Lars Køber, Christian Hassager, Jesper Kjærgaard   +9 more
wiley   +1 more source

Thiazides in kidney transplant recipients : skin in the game

Clinical trial data suggest that thiazides and thiazide-like drugs could be beneficial for blood-pressure lowering in patients with severe chronic kidney disease.
Van Laecke, Steven
core   +1 more source

Thiazide diuretics and the risk of hip fracture after stroke: a population-based propensity-matched cohort study using Taiwan’s National Health Insurance Research Database

, 2017
ObjectivesThis study aimed to investigate the association between thiazide use and the risk of hip fracture after stroke.SettingA population-based, propensity-matched cohort study was conducted on the basis of Taiwan’s National Health Insurance Research ...
Huei-Kai Huang, Shih-Hsien Yang, Shu-Man Lin, Chung-Chao Liang, Hung-Yu Cheng   +4 more
core   +1 more source

Discontinuation of SGLT2i After a Urogenital Infection: A Population‐Based Matched Cohort Study of Patients With Type 2 Diabetes

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5740-5750, July 2026.
ABSTRACT Aims Sodium‐glucose cotransporter 2 inhibitors (SGLT2is) improve glycaemic control and cardiorenal outcomes in Type 2 diabetes, particularly in patients at elevated cardiovascular and kidney risk, yet discontinuation following infections appears common.
Christine Ljungberg, Mette Nørgaard, Christina Vandenbroucke‐Grauls, Michael Dalager‐Pedersen, Henrik Toft Sørensen, Reimar Wernich Thomsen   +5 more
wiley   +1 more source

METABOLIC ALKALEMIA IN HYPERCALCIURIA STONE FORMERS: DOES IT MATTER?

Kidney & Blood Pressure Research
TThe literature lacks whether metabolic alkalemia occurs in outpatients with hypercalciuric nephrolithiasis. Thus, we aim to investigate it because these patients are often treated with thiazides to reduce urinary calcium excretion.
Renato V. M. Starek, Samirah A. Gomes, Claudia M.B. Helou   +2 more
doaj   +1 more source

Thiazide Diuretics Directly Induce Osteoblast Differentiation and Mineralized Nodule Formation by Interacting with a Sodium Chloride Co-Transporter in Bone

, 2007
International audienceThiazide diuretics are used worldwide as a first-choice drug for patients with uncomplicated hypertension. In addition to their antihypertensive effect, thiazides increase bone mineral density and reduce the prevalence of fractures.
Dvorak, Melita M., Kemp, Paul, Melita M. Dvorak, Dvorak, Melita, Pisitkun, Trairak, Riccardi, Daniela, Carter, D. Howard, Trairak Pisitkun, Knepper, Mark, Gerardo Gamba, Paul J. Kemp, Cyrille De Joussineau, D. Howard Carter, Mark A. Knepper, Daniela Riccardi, Kemp, Paul J., Carter, D Howard, Gamba, Gerardo, Knepper, Mark A., de Joussineau, Cyrille   +19 more
core   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Efficacy of chlorthalidone and hydrochlorothiazide in combination with amiloride in multiple doses on blood pressure in patients with primary hypertension: a protocol for a factorial randomized controlled trial

Trials, 2019
Background Thiazide diuretics have demonstrated favorable blood pressure lowering efficacy, but the equivalent doses of their more common agents, chlorthalidone and hydrochlorothiazide, are still unclear.
Vítor Magnus Martins, Lucas Helal, Filipe Ferrari, Leonardo Grabinski Bottino, Sandra Costa Fuchs, Flávio Danni Fuchs   +5 more
doaj   +1 more source

Effect of thiazides on colonic NaCl absorption: role of carbonic anhydrase

, 1991
The mechanisms by which the benzothiadiazide class of diuretics inhibit electroneutral NaCl absorption are not fully understood. We studied the mechanisms of thiazide action in perfused loops of distal colon in anesthetized male Sprague-Dawley rats ...
A. N. Charney, D. S. Goldfarb, A. J. Chan, D. Hernandez   +3 more
core   +1 more source

Effect of Diuretics on Cutaneous Squamous Cell Carcinoma: Clinical and Translational Evidence

International Journal of Dermatology, EarlyView.
Kevin Sheng‐Kai Ma, Stefano Sol, Fabiana Boncimino, Serena Yun‐Chen Tsai, Bethany J. Brumbaugh, Anna Mandinova, Steven T. Chen   +6 more
wiley   +1 more source