Results 81 to 90 of about 11,021 (223)

Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers.

PLoS ONE, 2019
BackgroundHypertension (HTN) disproportionately affects African Americans (AAs), who respond better to thiazide diuretics than other antihypertensives. Variants of the APOL1 gene found in AAs are associated with a higher rate of kidney disease and play a
Patrick N Cunningham, Zhiying Wang, Megan L Grove, Rhonda M Cooper-DeHoff, Amber L Beitelshees, Yan Gong, John G Gums, Julie A Johnson, Stephen T Turner, Eric Boerwinkle, Arlene B Chapman   +10 more
doaj   +1 more source

Improving prescribing of antihypertensive and cholesterol-lowering drugs: a method for identifying and addressing barriers to change [PDF]

, 2004
Background We describe a simple approach we used to identify barriers and tailor an intervention to improve pharmacological management of hypertension and hypercholesterolaemia.
Atle Fretheim, Andrew D Oxman, Signe Flottorp, JM Grimshaw, AD Oxman, AD Oxman, A Fretheim, A Fretheim, A Fretheim, A Fretheim, A Fretheim, Norwegian Institute of Public Health, A Svilaas, A Westheim, S Flottorp, IB Scheel, MJ Bass, RA Rossi, HI Goldberg, M Maclure, JN Aucott, AA Montgomery, I Hetlevik, JG Demakis, T van der Weijden, JA Skolbekken, SB Soumerai, S Flottorp, D Evans, JE Hux, B Santoso, J Avorn, SR Majumdar, J Avorn, LC Leviton, D Ross-Degnan, L Forsetlund, IB Scheel, R Baker, M Cranney   +39 more
core   +2 more sources

Emerging risk factors influencing the occurrence of peri‐implantitis

Periodontology 2000, EarlyView.
Abstract Background The objective of the present review is to explore the evidence and biological plausibility of factors that may expose dental implants to a greater likelihood of developing peri‐implantitis. Material and Methods An electronic screening on the PubMed library the was carried out to identify potential emerging factors that influence the
Alberto Monje, Ronald E. Jung, Cristina Valles, Nadja Naenni   +3 more
wiley   +1 more source

Ablation of the Cl-/HCO3- Exchanger Pendrin Enhances Hydrochlorothiazide-Induced Diuresis

Kidney & Blood Pressure Research, 2017
Background/Aims: The Cl-/HCO3- exchanger pendrin and the thiazide-sensitive Na-Cl cotransporter NCC are expressed in the kidney distal nephron and mediate salt absorption.
Saeed Alshahrani, Manoocher Soleimani
doaj   +1 more source

Detection of renal tubular transporter proteins in canine urinary extracellular vesicles using liquid chromatography–tandem mass spectrometry

Veterinary Clinical Pathology, EarlyView.
Abstract Urinary extracellular vesicles (UEVs) are membranous particles that carry renal tubular transporter proteins. Here, we evaluate whether selected renal tubular transporter proteins can be detected in UEVs isolated from small volume (1–5 mL) canine urine samples of healthy dogs and canine patients with elevated circulating parathyroid hormone ...
L. J. McGravey, P. R. Antrobus, T. L. Williams   +2 more
wiley   +1 more source

Intravenous Tolvaptan Sodium Phosphate Can Fail to Improve Fluid Overload Due to Heart Failure in Patients With Chronic Kidney Disease: A Case Report

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Takaya Uno, Ichiro Nakakura, Akari Ikeda, Atsuki Hosoda, Yutaro Mukai, Kaori Yamanishi, Naohiro Ohara, Kaori Imanishi, Yoshiko Une, Satoshi Yokoyama, Kouichi Hosomi   +10 more
wiley   +1 more source

Prevalence and impact of prescribing cascades in community‐dwelling adults: Longitudinal analysis of the Irish longitudinal study on ageing (TILDA)

British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1500-1508, May 2026.
Prescribing cascades occur when medication is prescribed to prevent/treat the adverse effects of another medication and may be intentional/unintentional. This study examines the prevalence of nine prescribing cascades (ThinkCascades) in The Irish Longitudinal StuDy on Ageing (TILDA).
Ann Sinéad Doherty, Rose Anne Kenny, Frank Moriarty, Fiona Boland, Barbara Clyne, Tom Fahey, Denis O' Mahony, Emma Wallace   +7 more
wiley   +1 more source

METABOLIC ALKALEMIA IN HYPERCALCIURIA STONE FORMERS: DOES IT MATTER?

Kidney & Blood Pressure Research
TThe literature lacks whether metabolic alkalemia occurs in outpatients with hypercalciuric nephrolithiasis. Thus, we aim to investigate it because these patients are often treated with thiazides to reduce urinary calcium excretion.
Renato V. M. Starek, Samirah A. Gomes, Claudia M.B. Helou   +2 more
doaj   +1 more source

The major changes in medical practice in the 20th century [PDF]

, 2000
One could truly say that there were more advances in medicine in the last 60 years than there had been in the previous 500 years. Indeed the medical breakthroughs of the last 50 years have probably saved more lives than those of any epoch since medicine ...
Fenech, Frederick F.
core  

Return to the workforce following first hospitalization for heart failure: a Danish nationwide cohort study [PDF]

, 2016
Background: Return to work is important financially, as a marker of functional status and for self-esteem in patients developing chronic illness. We examined return to work after first heart failure (HF) hospitalization.
Fosbøl, Emil L., Gerds, Thomas A., Gislason, Gunnar H., Jhund, Pardeep S., Kragholm, Kristian, Kristensen, Søren L., Køber, Lars, Lamberts, Morten, McMurray, John J.V., Mogensen, Ulrik M., Petrie, Mark C., Rørth, Rasmus, Torp-Pedersen, Christian, Wong, Chih   +13 more
core   +2 more sources