Results 141 to 150 of about 46,327 (259)

Current Perspectives on STING Agonists for Anticancer Drug Development

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
The molecular structures of STING agonists play a decisive role in regulating the STING pathway. Their distinct scaffolds and functional groups orchestrate receptor binding, conformational activation, and the subsequent immune response. ABSTRACT The cyclic GMP‐AMP (cGAS) synthase and stimulator of interferon genes signaling pathway plays a central role
Dilay Kahvecioglu Cicek
wiley   +1 more source

Chemoselective C-Terminal Activation Platform for Direct Conversion of Native Linear Peptides into Thiazoline/Thiazole Macrocycles. [PDF]

Org Lett
Le BQG, Kwon M, Raj M.
europepmc   +1 more source

The Rise of Stemphylium vesicarium: A Growing Threat to Pear Production in Europe

Plant Pathology, Volume 75, Issue 4, July‐August 2026.
Brown spot of pear, caused by the fungus Stemphylium vesicarium, was reported in Italy in 1975 and only recently, due to climate change and pesticide restrictions, it became a major threat for European pear production. New knowledge on this pathogen can allow the advent of new and effective control strategies.
Xueqin Chen, Milan Karas, Luca Dondini, Riccardo Baroncelli, Marina Collina, Elena Baraldi   +5 more
wiley   +1 more source

G-quartet driven adaptive hydrogels that integrate constitutional dynamics for antibacterial action and tissue repair. [PDF]

iScience
Mondal S, Lala B, Biswas D, Lehn JM, Dash J.   +4 more
europepmc   +1 more source

Design, Synthesis of Novel Quinazolinone Derivatives and Evaluation of EGFR Kinase Inhibition Activity via In Vitro and In Silico Studies. [PDF]

Chem Biol Drug Des
Kaya AZ, Evren AE, Akalın-Çiftçi G, Yurttaş L.   +3 more
europepmc   +1 more source

Design, Synthesis, Biological Evaluation, and Molecular Modeling Studies of Novel 2-Aminothiazole Derivatives as Potential FOXM1 Inhibitors for Triple-Negative Breast Cancer Therapy and Structure-Activity Relationship. [PDF]

Drug Dev Res
Abusharkh KAN, Çınar V, Onder A, Sıkık M, Mustafa Guzel, Hamurcu Z, Ozpolat B, Ay M, Comert Onder F.   +8 more
europepmc   +1 more source

Novel benzothiazole-indole acetamides as potential anticancer agents: synthesis, biological evaluation, and <i>in silico</i> studies. [PDF]

RSC Adv
Motamedi Shakib N, Negahdaripour M, Sayahi MH, Dastyafteh N, Dehghani Z, Emami M, Safapoor S, Ghasemi Y, Ghafouri SN, Ghahramani A, Mohajeri-Tehrani MR, Larijani B, Mahdavi M, Ranjbar S.   +13 more
europepmc   +1 more source

A Review of Recent Advances in the Anticancer Mechanisms of Activity of Novel Thiazoles and 4-Thiazolidinones/Thiazolidinediones (2021-2025). [PDF]

Molecules
Dudchak R, Podolak M, Bielawska A, Bielawski K, Lesyk R.   +4 more
europepmc   +1 more source

Coumarin thiazole-derived Schiff base copper complex: synthesis, characterization, and applications in the catalytic degradation of dyes, pearl millet seed germination for improved agricultural output and antioxidant assays. [PDF]

RSC Adv
Sharma N, Kanchan, Shrivastava R.
europepmc   +1 more source

Quinoline/thiazole compounds as selective acetylcholinesterase inhibitors: synthesis and biological assessment. [PDF]

RSC Med Chem
Kurban B, Osmaniye D, Levent S, Özkay Y, Kaplancıklı ZA.   +4 more
europepmc   +1 more source