Results 11 to 20 of about 9,832 (211)
A rapid synthesis of hydrazinyl thiazoles under solvent and catalyst free condition is reported within 30 s. A series of aryl ketones/4-benzoyl pyridine thiosemicarbazone, thiosemicarbazide and α-haloketones were used.
D. Chinnaraja, R. Rajalakshmi
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Scientific Opinion on the safety and efficacy of thiazoles, thiophene, thiazoline and thienyl derivatives (chemical group 29): 3-acetyl-2,5-dimethylthiophene when used as a flavouring for all animal species [PDF]
The current opinion concerns only one of the compounds belonging to chemical group 29, 3-acetyl-2,5-dimethylthiophene. 3-Acetyl-2,5-dimethylthiophene is genotoxic in vitro and in vivo.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
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A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO2
Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO2) oxidation of the corresponding thiazolines.
Bin Fu +4 more
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The Panel on Food Additives and Flavourings (FAF) was requested to consider the JECFA evaluations of 28 flavouring substances in the Flavouring Group Evaluation 76 (FGE.76Rev2). Twenty‐one of these substances have been considered in FGE.76Rev1.
EFSA Panel on Food Additives and Flavourings (FAF) +26 more
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Thiazoles inhibit reactive oxygen and nitrogen species mediated diabetes mellitus: integrated in vitro and in silico insights [PDF]
Thiazole heterocycles, characterized by their unique combination of sulfur and nitrogen atoms, have emerged as versatile scaffolds in medicinal chemistry.
Hamid Aziz
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Thiazole derivatives attract the attention of scientists both in the field of organic synthesis and bioactivity research due to their high biological activity.
Birutė Sapijanskaitė-Banevič +4 more
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Vergleich der Dissoziationskonstanten von 2-Amino-thiazol- und 2-Amino-oxazol-Derivaten
A description is given for the synthesis by standard methods of 2-Amino-4-phenyl- and 2-Amino-5-phenyl-thiazoles having different para-substituents together with the 2-Amino-4-phenyl-oxazole analogues. The pKa-values were determined for the compounds in
U. Stauss, H.P. Härter, O. Schindler
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Thiazole Ring—A Biologically Active Scaffold
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical applications. Its derivatives have a wide range of biological activities such as antioxidant, analgesic, and antimicrobial including antibacterial, antifungal ...
Anthi Petrou +2 more
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Neuere heterocyclische Zwischenprodukte für die Azokupplung durch Cyclisierung von Nitrilen
Two types of syntheses of heteroaromatic amines by cyclization of nitriles are described. It is dealt with the cyclization of nitriles by elemental sulphur yielding thiophenes and thiazoles and with some reactions of the resulting 2-amino-thiophene-3 ...
Karl Gewald
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Thiazole formation through a modified Gewald reaction
The synthesis of thiazoles and thiophenes starting from nitriles, via a modified Gewald reaction has been studied for a number of different substrates. 1,4-Dithiane-2,5-diol was used as the aldehyde precursor to give either 2-substituted thiazoles or 2 ...
Carl J. Mallia +3 more
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