Results 11 to 20 of about 9,832 (211)

A facile, solvent and catalyst free, microwave assisted one pot synthesis of hydrazinyl thiazole derivatives

open access: yesJournal of Saudi Chemical Society, 2015
A rapid synthesis of hydrazinyl thiazoles under solvent and catalyst free condition is reported within 30 s. A series of aryl ketones/4-benzoyl pyridine thiosemicarbazone, thiosemicarbazide and α-haloketones were used.
D. Chinnaraja, R. Rajalakshmi
doaj   +1 more source

Scientific Opinion on the safety and efficacy of thiazoles, thiophene, thiazoline and thienyl derivatives (chemical group 29): 3-acetyl-2,5-dimethylthiophene when used as a flavouring for all animal species [PDF]

open access: yesEFSA Journal, 2013
The current opinion concerns only one of the compounds belonging to chemical group 29, 3-acetyl-2,5-dimethylthiophene. 3-Acetyl-2,5-dimethylthiophene is genotoxic in vitro and in vivo.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO2

open access: yesMolecules, 2009
Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO2) oxidation of the corresponding thiazolines.
Bin Fu   +4 more
doaj   +1 more source

Flavouring Group Evaluation 76 Revision 2 (FGE.76Rev2): Consideration of sulfur‐containing heterocyclic compounds, evaluated by JECFA, structurally related to thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical group 29 and miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21Rev5

open access: yesEFSA Journal, 2023
The Panel on Food Additives and Flavourings (FAF) was requested to consider the JECFA evaluations of 28 flavouring substances in the Flavouring Group Evaluation 76 (FGE.76Rev2). Twenty‐one of these substances have been considered in FGE.76Rev1.
EFSA Panel on Food Additives and Flavourings (FAF)   +26 more
doaj   +1 more source

Thiazoles inhibit reactive oxygen and nitrogen species mediated diabetes mellitus: integrated in vitro and in silico insights [PDF]

open access: yesRSC Advances
Thiazole heterocycles, characterized by their unique combination of sulfur and nitrogen atoms, have emerged as versatile scaffolds in medicinal chemistry.
Hamid Aziz
doaj   +1 more source

Synthesis, Characterization and Bioassay of Novel Substituted 1-(3-(1,3-Thiazol-2-yl)phenyl)-5-oxopyrrolidines

open access: yesMolecules, 2020
Thiazole derivatives attract the attention of scientists both in the field of organic synthesis and bioactivity research due to their high biological activity.
Birutė Sapijanskaitė-Banevič   +4 more
doaj   +1 more source

Vergleich der Dissoziationskonstanten von 2-Amino-thiazol- und 2-Amino-oxazol-Derivaten

open access: yesCHIMIA, 1973
A description is given for the synthesis by standard methods of 2-Amino-4-phenyl- and 2-Amino-5-phenyl-thiazoles having different para-substituents together with the 2-Amino-4-phenyl-oxazole analogues. The pKa-values were determined for the compounds in
U. Stauss, H.P. Härter, O. Schindler
doaj   +1 more source

Thiazole Ring—A Biologically Active Scaffold

open access: yesMolecules, 2021
Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical applications. Its derivatives have a wide range of biological activities such as antioxidant, analgesic, and antimicrobial including antibacterial, antifungal ...
Anthi Petrou   +2 more
doaj   +1 more source

Neuere heterocyclische Zwischenprodukte für die Azokupplung durch Cyclisierung von Nitrilen

open access: yesCHIMIA, 1980
Two types of syntheses of heteroaromatic amines by cyclization of nitriles are described. It is dealt with the cyclization of nitriles by elemental sulphur yielding thiophenes and thiazoles and with some reactions of the resulting 2-amino-thiophene-3 ...
Karl Gewald
doaj   +1 more source

Thiazole formation through a modified Gewald reaction

open access: yesBeilstein Journal of Organic Chemistry, 2015
The synthesis of thiazoles and thiophenes starting from nitriles, via a modified Gewald reaction has been studied for a number of different substrates. 1,4-Dithiane-2,5-diol was used as the aldehyde precursor to give either 2-substituted thiazoles or 2 ...
Carl J. Mallia   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy