Results 21 to 30 of about 9,794 (211)
EFSA Journal, 2023 The Panel on Food additives and Flavourings (FAF) was requested to evaluate the flavouring substances 2,4‐dimethyl‐3‐thiazoline [FL‐no: 15.060] and 2‐isobutyl‐3‐thiazoline [FL‐no: 15.119] in Flavouring Group Evaluation 21 revision 6 (FGE.21Rev6).
EFSA Panel on Food Additives and Flavourings (FAF) +25 more
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IUCrData, 2022 The title compound, C29H25N3O3S, crystallizes in the monoclinic space group P21/n. The molecule contains a central four-ring system in which all of the rings are almost coplanar.
Sreeramapura D. Archana +5 more
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Journal of Saudi Chemical Society, 2023 Several new thiazole derivatives linked pyrazole and/or pyridine rings were synthesized based on the versatile precursor 2-(5-acetyl-4-methyl-3-phenylthiazol-2(3H)-ylidene)acetonitrile (1). The synthesized derivatives were optimized using DFT approach in order to inspect the configurations and energies of the HOMO-LUMO orbitals.
Abrar Bayazeed +7 more
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The Structure of Biologically Active Functionalized Azoles: NMR Spectroscopy and Quantum Chemistry
Magnetochemistry, 2022 This review summarizes the data on the stereochemical structure of functionalized azoles (pyrazoles, imidazoles, triazoles, thiazoles, and benzazoles) and related compounds obtained by multipulse and multinuclear 1H, 13C, 15N NMR spectroscopy and quantum
Lyudmila I. Larina
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Development of Novel Pyridine-Thiazole Hybrid Molecules as Potential Anticancer Agents
Molecules, 2022 Novel pyridine-thiazole hybrid molecules were synthesized and subjected to physico-chemical characterization and screening of their cytotoxic action towards a panel of cell lines derived from different types of tumors (carcinomas of colon, breast, and ...
Iryna Ivasechko +15 more
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Biosynthesis of the Thiamin-Thiazole in Eukaryotes: Identification of a Thiazole Tautomer Intermediate [PDF]
Journal of the American Chemical Society, 2008 Thiamin thiazole biosynthesis in eukaryotes is still not completely understood. In this report, a late intermediate, tightly bound to the active site of the Saccharomyces cerevisiae thiazole synthase, was identified as an adenylated thiazole tautomer. The reactivity of this unusual compound was evaluated.
Abhishek, Chatterjee +4 more
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Journal of Saudi Chemical Society, 2015 A rapid synthesis of hydrazinyl thiazoles under solvent and catalyst free condition is reported within 30 s. A series of aryl ketones/4-benzoyl pyridine thiosemicarbazone, thiosemicarbazide and α-haloketones were used.
D. Chinnaraja, R. Rajalakshmi
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A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO2
Molecules, 2009 Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO2) oxidation of the corresponding thiazolines.
Bin Fu +4 more
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Synthesis and Biological Evaluation of Bisthiazoles and Polythiazoles
Molecules, 2018 Small heterocyclic compounds containing nitrogen and sulfur atoms, such as thiazole derivatives, represent a significant class of organic azoles that exhibit promising bioactivities and have a great potential in medicinal and agricultural fields.
Mohammed A. Al-Omair +2 more
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Thiazole formation through a modified Gewald reaction
Beilstein Journal of Organic Chemistry, 2015 The synthesis of thiazoles and thiophenes starting from nitriles, via a modified Gewald reaction has been studied for a number of different substrates. 1,4-Dithiane-2,5-diol was used as the aldehyde precursor to give either 2-substituted thiazoles or 2 ...
Carl J. Mallia +3 more
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