Results 21 to 30 of about 12,572 (245)

5-(4-Methoxyphenyl)-1-[4-(4-methoxyphenyl)thiazol-2-yl]-3-[4-(prop-2-ynyloxy)phenyl]-4,5-dihydro-1H-pyrazole

IUCrData, 2022
The title compound, C29H25N3O3S, crystallizes in the monoclinic space group P21/n. The molecule contains a central four-ring system in which all of the rings are almost coplanar.
Sreeramapura D. Archana, Holalagudu A. Nagma Banu, Balakrishna Kalluraya, Hemmige S. Yathirajan, Rishik Balerao, Ray J. Butcher   +5 more
doaj   +1 more source

The Structure of Biologically Active Functionalized Azoles: NMR Spectroscopy and Quantum Chemistry

Magnetochemistry, 2022
This review summarizes the data on the stereochemical structure of functionalized azoles (pyrazoles, imidazoles, triazoles, thiazoles, and benzazoles) and related compounds obtained by multipulse and multinuclear 1H, 13C, 15N NMR spectroscopy and quantum
Lyudmila I. Larina
doaj   +1 more source

Development of Novel Pyridine-Thiazole Hybrid Molecules as Potential Anticancer Agents

Molecules, 2022
Novel pyridine-thiazole hybrid molecules were synthesized and subjected to physico-chemical characterization and screening of their cytotoxic action towards a panel of cell lines derived from different types of tumors (carcinomas of colon, breast, and ...
Iryna Ivasechko, Ihor Yushyn, Piotr Roszczenko, Julia Senkiv, Nataliya Finiuk, Danylo Lesyk, Serhii Holota, Robert Czarnomysy, Olga Klyuchivska, Dmytro Khyluk, Nataliya Kashchak, Andrzej Gzella, Krzysztof Bielawski, Anna Bielawska, Rostyslav Stoika, Roman Lesyk   +15 more
doaj   +1 more source

Selective C-H Chalcogenation of Thiazoles via Thiazol-2-yl-phosphonium Salts [PDF]

, 2020
Thiazoles and benzothiazoles undergo regioselective C2-H chalcogenation via the sequence of thiazole C2-functionalization with phosphines to produce phosphonium salts which in turn react with S- and Se-centered nucleophiles to give products of C2-H ...
Konrad, Wagner, Konrad Wagner (8617630), Ivan Vilotijevic (7541342), Fritz, Schömberg, You Zi (8588118), Fritz Schömberg (8617633), You, Zi, Ivan, Vilotijevic   +7 more
core   +1 more source

Scientific Opinion on the safety and efficacy of thiazoles, thiophene, thiazoline and thienyl derivatives (chemical group 29): 3-acetyl-2,5-dimethylthiophene when used as a flavouring for all animal species [PDF]

EFSA Journal, 2013
The current opinion concerns only one of the compounds belonging to chemical group 29, 3-acetyl-2,5-dimethylthiophene. 3-Acetyl-2,5-dimethylthiophene is genotoxic in vitro and in vivo.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

In silico ADMET prediction, evaluation of cytotoxicity in mouse splenocytes and preliminary evaluation of in vitro antimalarial activity of 4-(4-chlorophenyl)thiazole compounds [PDF]

Anais da Academia Brasileira de Ciências, 2023
In this work, an in silico study and evaluation of the cytotoxicity of 4-(4-chlorophenyl)thiazole compounds against mouse splenocytes and the chloroquine-sensitive Plasmodium falciparum 3D7 strain are reported.
BEATRIZ R.M.G. DA SILVA, NATANAEL DA SILVA BEZERRA JÚNIOR, JAMERSON F. DE OLIVEIRA, DENISE MARIA F.A. DUARTE, DIEGO S.C. MARQUES, FÁTIMA NOGUEIRA, MARIA CARMO A. DE LIMA, IRANILDO JOSÉ DA CRUZ FILHO   +7 more
doaj   +1 more source

Some addition reactions of thiazoles [PDF]

, 2018
Possible synthetic approaches to the pyrrolo[2,1-b]thiazole system have been investigated involving the mode of addition of thiazoles to dimethyl acetylenedicarboxylate.
Skelton, Frederick Stevens
core   +2 more sources

A facile, solvent and catalyst free, microwave assisted one pot synthesis of hydrazinyl thiazole derivatives

Journal of Saudi Chemical Society, 2015
A rapid synthesis of hydrazinyl thiazoles under solvent and catalyst free condition is reported within 30 s. A series of aryl ketones/4-benzoyl pyridine thiosemicarbazone, thiosemicarbazide and α-haloketones were used.
D. Chinnaraja, R. Rajalakshmi
doaj   +1 more source

Flavouring Group Evaluation 76 Revision 2 (FGE.76Rev2): Consideration of sulfur‐containing heterocyclic compounds, evaluated by JECFA, structurally related to thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical group 29 and miscellaneous substances from chemical group 30 evaluated by EFSA in FGE.21Rev5

EFSA Journal, 2023
The Panel on Food Additives and Flavourings (FAF) was requested to consider the JECFA evaluations of 28 flavouring substances in the Flavouring Group Evaluation 76 (FGE.76Rev2). Twenty‐one of these substances have been considered in FGE.76Rev1.
EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Gisela Degen, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Melania Manco, Peter Moldeus, Sabina Passamonti, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, Romualdo Benigni, Claudia Bolognesi, Kevin Chipman, Eugenia Cordelli, Karin Nørby, Camilla Svendsen, Maria Carfí, Giorgia Vianello, Wim Mennes   +26 more
doaj   +1 more source

Synthesis, Characterization and Bioassay of Novel Substituted 1-(3-(1,3-Thiazol-2-yl)phenyl)-5-oxopyrrolidines

Molecules, 2020
Thiazole derivatives attract the attention of scientists both in the field of organic synthesis and bioactivity research due to their high biological activity.
Birutė Sapijanskaitė-Banevič, Božena Šovkovaja, Rita Vaickelionienė, Jūratė Šiugždaitė, Eglė Mickevičiūtė   +4 more
doaj   +1 more source