Results 221 to 230 of about 44,849 (251)
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Organization of myosin molecules in the muscle thick filament

Experientia, 1976
Tryptic treatment of muscle thick filaments reveals the underlying backbones of aggregatedl-meromyosin as a coli of 3 secondary filaments (helical repeat ∼ 130 nm) each in turn a coli of a 3 finer ones.
C L, Davey, A E, Graafhuis
openaire   +2 more sources

Thick and Thin Filaments in Postmitotic, Mononucleated Myoblasts

Science, 1975
Addition of cytochalasin B to primary muscle cultures allows the physical separation of postmitotic myogenic cells from replicating presumptive myoblasts and replicating fibroblasts. Mononucleated, postmitotic myoblasts proceed without fusion to synthesize myosin and actin and to assemble these proteins into thick and thin filaments.
H, Holtzer   +4 more
openaire   +2 more sources

The structure of the paramyosin core in molluscan thick filaments

Journal of Muscle Research and Cell Motility, 1981
The thick filaments of molluscan muscles have been examined by electron microscopy and X-ray diffraction in order to test whether the structure of the paramyosin core is crystalline and not helicoidal. In accurately cut transverse sections of the white adductor muscle of the oyster the thick filaments are uniformly stained but, when the sections are ...
P M, Bennett, A, Elliott
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Assemblages of multiple thick filaments in nematode mutants

Journal of Muscle Research and Cell Motility, 1987
A spectrum of thick filament-related structures exhibiting novel structural features is isolated in addition to the normal thick filaments from unc-15 and unc-82 mutants of Caenorhabditis elegans. Many assemblages have multiple myosin-coated filaments extending from both ends of central domains exhibiting paracrystalline paramyosin.
H F, Epstein, I, Ortiz, G C, Berliner
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Thick-Filament Degeneration Associated With Periarteritis Nodosa

Archives of Neurology, 1982
• Absence of thick filaments from A bands in 30% of myofibers, which gave apparently normal histochemical reactions for myosin adenosine triphosphatase, was seen in a case of periarteritis nodosa. The pathogenesis of the condition remains uncertain, but immunologic, toxic, or viral causation may be involved.
I, Halperin   +4 more
openaire   +2 more sources

Phosphofructokinase: a component of the thick filament?

Advances in experimental medicine and biology, 1988
F-protein, a consistent contaminant of myosin preparations, has been shown to be phosphofructokinase, the key regulatory enzyme of glycolysis. In homogenates of rigor muscle most of the phosphofructokinase sediments with the myofibrils, suggesting that in the living muscle cell phosphofructokinase is not in the soluble fraction as was formerly thought,
G, Offer, R, Starr, J, Trinick
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Structure of the Myosin Thick Filaments in Muscle

Striated muscle is composed of overlapping arrays of thick myosin filaments and thin actin filaments. The thick filaments are composed of myosin molecules, which are hexamers of two heavy chains and two pairs of light chains. The heavy chain has an N-terminal head domain and a C-terminal helical rod domain.
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Proteins of the Thick Filament

1989
A.M. Pearson, R.B. Young
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