Results 211 to 220 of about 424,053 (243)

Thick filaments of striated muscle are laterally interconnected

Journal of Ultrastructure and Molecular Structure Research, 1988
Earlier reports from this and other laboratories indicated that thick filaments may be interconnected along their length by rung-like structures. This study was carried out to test whether these interconnections are genuine structures; whether they appear in different muscle types; and whether they arise from myosin cross-bridges.
P H, Baatsen, K, Trombitás, G H, Pollack   +2 more
openaire   +2 more sources

An immunochemical approach to the structure of myosin and the thick filament

Journal of Molecular Biology, 1972
Abstract The arrangement of the various components of myosin within the myofibril has been investigated by staining the thick filament with fluorescein-labeled antibodies directed against myosin and its “subunits”, heavy meromyosin S-1, rod and light chains.
S, Lowey, L A, Steiner
openaire   +2 more sources

Thick filament degeneration in a case of acute quadriplegia

Journal of the Neurological Sciences, 1980
Absence of thick filaments from the A bands in tissue giving apparently normal histochemical reactions for myosin ATPase, was seen in a case of acute onset muscle weakness progressing rapidly to quadriplegia with cerebral involvement. There was also widespread degeneration of interstitial structures and much phagocytosis.
R, Yarom, A, Reches
openaire   +2 more sources

Thick and Thin Filaments in Postmitotic, Mononucleated Myoblasts

Science, 1975
Addition of cytochalasin B to primary muscle cultures allows the physical separation of postmitotic myogenic cells from replicating presumptive myoblasts and replicating fibroblasts. Mononucleated, postmitotic myoblasts proceed without fusion to synthesize myosin and actin and to assemble these proteins into thick and thin filaments.
H, Holtzer, K, Strahs, J, Biehl, A P, Somlyo, H, Ishikawa   +4 more
openaire   +2 more sources

Assemblages of multiple thick filaments in nematode mutants

Journal of Muscle Research and Cell Motility, 1987
A spectrum of thick filament-related structures exhibiting novel structural features is isolated in addition to the normal thick filaments from unc-15 and unc-82 mutants of Caenorhabditis elegans. Many assemblages have multiple myosin-coated filaments extending from both ends of central domains exhibiting paracrystalline paramyosin.
H F, Epstein, I, Ortiz, G C, Berliner
openaire   +2 more sources

Phosphofructokinase: a component of the thick filament?

Advances in experimental medicine and biology, 1988
F-protein, a consistent contaminant of myosin preparations, has been shown to be phosphofructokinase, the key regulatory enzyme of glycolysis. In homogenates of rigor muscle most of the phosphofructokinase sediments with the myofibrils, suggesting that in the living muscle cell phosphofructokinase is not in the soluble fraction as was formerly thought,
G, Offer, R, Starr, J, Trinick
openaire   +1 more source

Thick-Filament Degeneration Associated With Periarteritis Nodosa

Archives of Neurology, 1982
• Absence of thick filaments from A bands in 30% of myofibers, which gave apparently normal histochemical reactions for myosin adenosine triphosphatase, was seen in a case of periarteritis nodosa. The pathogenesis of the condition remains uncertain, but immunologic, toxic, or viral causation may be involved.
I, Halperin, I, Kobrin, M, Ilsar, G, Lugassy, R, Yarom   +4 more
openaire   +2 more sources

Association of thin filaments into thick filaments revealing the structural hierarchy of amyloid fibrils

Journal of Structural Biology, 2005
Beta2-Microglobulin (beta2-m) is a major structural component of dialysis-related amyloid fibrils. Kozhukh et al. [J. Biol. Chem. 277 (2002) 1310] prepared a series of peptide fragments of beta2-m by the protease digestion and examined their ability to form amyloid fibrils in citrate buffer at pH 2.5.
Takashi, Kanno, Keiichi, Yamaguchi, Hironobu, Naiki, Yuji, Goto, Tomoji, Kawai   +4 more
openaire   +2 more sources

Structure of the Myosin Thick Filaments in Muscle

Striated muscle is composed of overlapping arrays of thick myosin filaments and thin actin filaments. The thick filaments are composed of myosin molecules, which are hexamers of two heavy chains and two pairs of light chains. The heavy chain has an N-terminal head domain and a C-terminal helical rod domain.
openaire   +2 more sources

[36] Motility Assays on Molluscan Native Thick Filaments thick filaments

1998
Yung Jin Han, James R. Sellers
openaire   +1 more source