Results 71 to 80 of about 53,903 (284)

Direct Measurements of Local Coupling between Myosin Molecules Are Consistent with a Model of Muscle Activation.

PLoS Computational Biology, 2015
Muscle contracts due to ATP-dependent interactions of myosin motors with thin filaments composed of the proteins actin, troponin, and tropomyosin.
Sam Walcott, Neil M Kad
doaj   +1 more source

Comparison of Triply Periodic Minimal Surface Energy Absorbers Under Uniaxial Compressive Loading

Advanced Engineering Materials, EarlyView.
This study investigates LCD 3D printed Triply Periodic Minimal Surface (TPMS) structures as mechanical energy absorbers. By comparing various base designs and layered combinations under uniaxial compression, it identifies that a Diamond‐Gyroid sandwich structure offers superior performance.
Sergej Grednev, Noah‐Lean Roschlaub, Anne Jung   +2 more
wiley   +1 more source

Structural evidence of tropomyosin in purified smooth muscle thin filaments from chicken gizzard

Journal of Analytical Science and Technology
Tropomyosin is one of the key components involved in actin–myosin interactions, which are essential for muscle contraction and regulation of cytoskeletal dynamics.
Anahita Vispi Bharda, Yoon Ho Park, Hyuntae Hong, Young Kwan Kim, Hyun Suk Jung   +4 more
doaj   +1 more source

Thin-filament transition rates (ξ = 100).

, 2012
Thin-filament transition rates (ξ = 100).
Thomas L. Daniel (109686), Michael Regnier (76653), Bertrand C. W. Tanner (165537)   +2 more
core   +1 more source

Stretching the Printability Metric in Direct‐Ink Writing with Highly Extensible Yield‐Stress Fluids

Advanced Functional Materials, EarlyView.
This study introduces “drawability” as a new metric for assessing printability in direct‐ink writing, focusing on gap‐spanning performance and speed robustness. By designing yield‐stress fluids with high extensibility, we demonstrate that extensional strain‐to‐break significantly enhances printability.
Chaimongkol Saengow, Samya Sen, Joaquin Yus, Eliza E. Lovrich, Amanda G. Hoika, Kelly M. Chang, Arielle A. Pfeil, Nellie Haug, Amy J. Wagoner Johnson, Randy H. Ewoldt   +9 more
wiley   +1 more source

Cryo-EM structures of cardiac muscle α-actin mutants M305L and A331P give insights into the structural mechanisms of hypertrophic cardiomyopathy

European Journal of Cell Biology
Cardiac muscle α-actin is a key protein of the thin filament in the muscle sarcomere that, together with myosin thick filaments, produce force and contraction important for normal heart function.
Hsiang-Ling Huang, Andrejus Suchenko, Giovanna Grandinetti, Mohan K. Balasubramanian, Krishna Chinthalapudi, Sarah M. Heissler   +5 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

A Model of Calcium Activation of the Cardiac Thin Filament [PDF]

Biochemistry, 2011
The cardiac thin filament regulates actomyosin interactions through calcium-dependent alterations in the dynamics of cardiac troponin and tropomyosin. Over the past several decades, many details of the structure and function of the cardiac thin filament and its components have been elucidated.
Edward P, Manning, Jil C, Tardiff, Steven D, Schwartz   +2 more
openaire   +2 more sources

Clinical Phenotype and Outcome of Hypertrophic Cardiomyopathy Associated With Thin-Filament Gene Mutations

, 2014
BackgroundMild hypertrophy but increased arrhythmic risk characterizes the stereotypic phenotype proposed for hypertrophic cardiomyopathy (HCM) caused by thin-filament mutations.
Tomberli, Benedetta, Coppini, Raffaele, Day, Sharlene, Tardiff, Jil, Bardi, Sara, Mugelli, Alessandro, Torricelli, Francesca, Ashley, Euan, Cecchi, Franco, Ferrantini, Cecilia, Girolami, Francesca, Ho, Carolyn Y., Poggesi, Corrado, Olivotto, Iacopo   +13 more
core   +1 more source

Mechanical Behavior and Fracture Mechanisms of MXene/PVDF Nanocomponsites: In Situ Characterization and Multiscale Analysis

Advanced Functional Materials, EarlyView.
Multiscale experiments and modeling reveal how Ti3C2Tx MXene nanosheets reinforce PVDF nanocomposites. An optimal MXene loading (∼1 wt.%) nearly doubles tensile strength through efficient stress transfer, flake alignment, and crack‐deflection mechanisms, transforming ductile polymer behavior into a controlled multi‐stage fracture pathway which aligns ...
Bita Soltan Mohammadlou, James FitzPatrick, Li Meng, Kateryna Shevchuk, Ahmad Najafi, Yury Gogotsi   +5 more
wiley   +1 more source