Methylthioadenosine phosphorylase (MTAP)-deficient T-cell ALL xenografts are sensitive to pralatrexate and 6-thioguanine alone and in combination [PDF]
core +1 more source
Investigating the Therapeutic Activity of C<sub>4</sub>N as a Targeted Drug Delivery System for Acetaminophen and Thioguanine through DFT Simulations. [PDF]
Nazeer M +5 more
europepmc +1 more source
Placing purines in precision medicine: Targeting a metabolic reliance in <i>KRAS</i>-mutant tumors. [PDF]
De Boni L +9 more
europepmc +1 more source
Development and Validation of a Sensitive Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Method for the Simultaneous Quantification of Thiopurine Nucleotides in Human Red Blood Cells. [PDF]
Singh M, Kaushal S, Gupta K, Sood A.
europepmc +1 more source
EPI-SauriCas9-based mouse ovarian cancer models recapitulating pten deletion in patients. [PDF]
Chen W +13 more
europepmc +1 more source
Influence of xanthine oxidase and inosine monophosphate dehydrogenase polymorphisms on 6-mercaptopurine treatment response in pediatric acute lymphoblastic leukemia. [PDF]
Sabirova Z +10 more
europepmc +1 more source
Development and Application of an LC-MS/MS Method for Simultaneous Quantification of Azathioprine and Its Metabolites: Pharmacokinetic and Microbial Metabolism Study of a Colon-Targeted Nanoparticle. [PDF]
Zhang J +5 more
europepmc +1 more source

