Results 91 to 100 of about 14,411 (229)
DNMTs are required for delayed genome instability caused by radiation [PDF]
, 2012 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited ...
Anderson, RM +10 more
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A New Electrochemical Sensor for Direct Detection of Purine Antimetabolites and DNA Degradation
Journal of Analytical Methods in Chemistry, 2019 The development of a reliable electrochemical sensor using a hybrid nanocomposite consisting of ionic liquid (1-butyl-3-methylimidazolium hexafluorophosphate) functionalized graphene oxide (GrO-IL) and gold nanoparticles (AuNPs) stabilized by chitosan ...
Liliya K. Shpigun, Elena Yu. Andryukhina
doaj +1 more source
Functional toxicology: tools to advance the future of toxicity testing [PDF]
, 2014 The increased presence of chemical contaminants in the environment is an undeniable concern to human health and ecosystems. Historically, by relying heavily upon costly and laborious animal-based toxicity assays, the field of toxicology has often ...
Brandon D. Gaytán, Chris D. Vulpe
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Electrochemical oxidation of 6-thioguanine
Journal of Electroanalytical Chemistry and Interfacial Electrochemistry, 1986 Abstract The electrochemical exidation pathway of 6-thioguanine was investigated by cyclic voltammetry, constant-potential electrolysis, coulometry, UV/VIS spectroscopy and mass spectrometry. Experimental evidence indicates that the oxidation pathway depends on potential.
Department of Chemistry, University of Florida Gainesville, FL 32611 U.S.A. ( host institution ) +2 more
openaire +2 more sources
PLoS ONE, 2019 BackgroundThe recently established association between higher levels of DNA-incorporated thioguanine nucleotides and lower relapse risk in childhood acute lymphoblastic leukaemia (ALL) calls for reassessment of prolonged 6-thioguanine (6TG) treatment ...
Linea Natalie Toksvang +6 more
doaj +1 more source
Suspected azathioprine induced liver cirrhosis: an unusual side effect
The Pan African Medical Journal, 2014 In recent years, the hepatotoxic potential of thiopurines, in particular 6-thioguanine (6-TG) has been discussed in literature. However, cirrhosis was exceptionally reported.
Aida Ben Slama Trabelsi +5 more
doaj +1 more source
Recent Advances in Cancer Chemotherapy [PDF]
, 1981 The present state of cancer chemotherapy can be reviewed in light of selected basic principles with an acknowledgement of the role of established chemotherapeutic agents.
Diasio, Robert B.
core +1 more source
, 2014 Purpose of review: Long-term survival of liver transplant recipients is threatened by increased rates of de-novo malignancy and recurrence of hepatocellular carcinoma (HCC), both events tightly related to immunosuppression.
Burroughs, AK +2 more
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Perspectives and Prospects in the Chemotherapy of Gastrointestinal Cancer [PDF]
, 1967 5-Flourouracil (5-FU) is the best agent for the treatment of all gastrointestinal cancers but should be used with restraint, since severe toxicity does not guarantee increased response or survival time.
Regelson, William
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The PML-RAR alpha transcript in long-term follow-up of acute promyelocytic leukemia patients [PDF]
, 2001 Background and Objectives. Detection of PML-RAR alpha transcripts by RT-PCR is now established as a rapid and sensitive method for diagnosis of acute promyelocytic leukemia (APL), Although the majority of patients in longterm clinical remission are ...
Carrara, P +11 more
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