Results 101 to 110 of about 10,117 (217)

6-Thioguanine is a noncompetitive and slow binding inhibitor of human deubiquitinating protease USP2

, 2018
Ubiquitin-specific protease 2 (USP2) belongs to the family of deubiquitinases that can rescue protein targets from proteasomal degradation by reversing their ubiquitination.
Hui-Chi Tang, Chiao-Yin Sun, Shang-Ju Chuang, Shu-Chun Cheng, Chi-Yuan Chou   +4 more
core   +1 more source

Mitigating UVA light induced reactivity of 6-thioguanine through formation of a Ru(II) half-sandwich complex

, 2014
The organometallic complex of (eta(6)-cymene)Ru(II)Br with 6-thioguanine (6-TG) shows better photostability than the biologically active 6-thioguanine which is used as an immunosuppressant and as an anticancer ...
Samuelson, Ashoka G, Mitra, Raja
core   +1 more source

6-Thioguanine for Crohn's disease during pregnancy: thiopurine metabolite measurements in both mother and child

, 2005
6-Thioguanine is used as an escape thiopurine for treating inflammatory bowel disease patients intolerant or refractory to azathioprine, 6-mercaptopurine or methotrexate. Case reports show conflicting data on the use of 6-thioguanine throughout pregnancy.
van Elburg, Ruurd M., Wilhelm, Abraham J., Mulder, Chris J. J., Remmink, Adriana J., van Bodegraven, Adriaan A., Wilhelm, A.J., Vugt, J.M.G. van, Bodegraven, A.A. van, van Elburg, R.M., Remmink, A.J., van Bodegraven, A.A., van Vugt, J.M.G., De Boer, NK, Elburg, R.M. van, Boer, NK De, Mulder, C.J.J., van Vugt, John M. G., de Boer, Nanne K. H.   +17 more
core   +1 more source

Insertion sites mapped in 6-thioguanine resistant mutants from library H3L1.

, 2013
Insertion sites mapped in 6-thioguanine resistant mutants from library H3L1.
Kerry Fenwick (41196), Farah L. Rehman (406999), Fredrik Wallberg (1954), Rachel Brough (96312), Stephen J. Pettitt (406998), Christopher J. Lord (123616), Ilirjana Bajrami (407000), James Campbell (81613), Alan Ashworth (1270), Ioannis Assiotis (179964), Lina Chen (87129), Iwanka Kozarewa (179955)   +11 more
core   +1 more source

6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy

BMC Microbiology
Background Enterovirus 71 (EV71) is one of the major causative agents of hand, foot, and mouth disease (HFMD), and can cause severe cerebral complications and even fatality in children younger than 5 years old.
Qiao You, Jing Wu, Ruining Lyu, Yurong Cai, Na Jiang, Ye Liu, Fang Zhang, Yating He, Deyan Chen, Zhiwei Wu   +9 more
doaj   +1 more source

The thiopurine methyltransferase genetic polymorphism is associated with thioguanine-related veno-occlusive disease of the liver in children with acute lymphoblastic leukemia.

, 2006
OBJECTIVE: Thiopurine metabolism was investigated in children with acute lymphoblastic leukemia treated in the United Kingdom Medical Research Council trial ALL97.
Vora, A, Lilleyman, JS, Mitchell, C, Richards, Susan, Lennard, L, Cartwright, CS   +5 more
core   +1 more source

Chronic eosinophilic leukemia with monosomy 8 in a five-year-old girl: a rare case

The Turkish Journal of Pediatrics, 2014
A 5-year-old girl was admitted to our hospital due to fatigue and fever lasting for six months. She had systolic murmur in the mesocardiac and apex regions and hepatosplenomegaly.
Meriç Kaymak-Cihan, Macit Arıyürek, Nural Kiper, Ayşenur Paç, Nazire Terzi, Serpil Dizbay-Sak, Işınsu Kuzu, Bilgin Arıbaş, Barış Kuşkonmaz, Ajlan Tükün, Lale Olcay   +10 more
doaj  

Cover 1 - Thioguanine Abrogated Colitis Cancer Model

Cellular and Molecular Gastroenterology and Hepatology, 2021
doaj   +1 more source

Thioguanine [PDF]

, 2020
openaire   +1 more source

Investigating the Therapeutic Activity of C₄N as a Targeted Drug Delivery System for Acetaminophen and Thioguanine through DFT Simulations. [PDF]

ACS Omega
Nazeer M, Yar M, Ayub K, Bayach I, Almutlaq N, Al Amer K.   +5 more
europepmc   +1 more source