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Synthesis of Thiohydantoin. III

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Solid-phase synthesis of branched thiohydantoin benzimidazolinethiones and branched thiohydantoin tetrahydroquinoxalinediones

Tetrahedron Letters, 2000
Abstract An efficient solid-phase synthesis method is described for branched thiohydantoin benzimidazolinethiones and branched thiohydantoin tetrahydroquinoxalinediones using 4-fluoro-3-nitrobenzoic acid.
Adel Nefzi   +2 more
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Hydantoins, thiohydantoins, glycocyamidines—36

Tetrahedron, 1973
Abstract In contrast to the α-chloroamides 1a-c which, when reacted with potassium N-cyanoanilide, furnish anomalous substitution products ( 2a-c ), the related nitrile and ester yields normal substitution products ( 3a and b ) under the same conditions.
Gy. Simig, K. Lempert, J. Tamás
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Thiohydantoins. VI. Hydrolysis of 1-acyl-2-thiohydantoins: reported anomalies

Canadian Journal of Chemistry, 1968
Two reports in which it was claimed that the 1-acyl group of a 1-acyl-2-thiohydantoin was not rapidly removed by dilute acid or alkali were investigated and found erroneous.
J. T. Edward, J. K. Liu
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Thiohydantoin Nucleosides. Synthesis Approaches

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Ahmed I. A. Khodair   +2 more
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5,5-Diphenyl-2-thiohydantoin

Acta Crystallographica Section C Crystal Structure Communications, 1998
The molecular structure of the title compound, 5,5-diphenyl-2-thioxoimidazolidin-4-one, C 15 H 12 N 2 OS, resembles that of 5,5-diphenylhydantoin (phenytoin). The C=S distance is 1.648 (2) A. The crystal structure consists of ribbon-like infinite sheets of molecules bonded by N-H...O and N-H...S hydrogen bonds.
A. W. Roszak, D. F. Weaver
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1-Acetyl-2-thiohydantoin

Acta Crystallographica Section C Crystal Structure Communications, 1998
In the title compound (1-acetyl-4-oxoimidazolidine-2-thione, C5H6N2O2S), the plane of the acetyl group forms an angle of 6.7° with the essentially planar thiohydantoin ring. N—H⋯O hydrogen bonds create quasiplanar chains of molecules along the y axis.
J. S. Casas   +5 more
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