Results 161 to 170 of about 1,063 (182)

Synthesis of 3‐Ω‐Amino‐2‐thiohydantoins.

ChemInform, 2003
AbstractIn the reaction of ethyl isothiocyanatoacetate with diamines, followed by cyclization of the intermediate product, 3‐monosubstituted thiohydantoins have been obtained. It was found that the reaction course depends on the purity of the isothiocyanate used and also, in the case of dialkylaminoamines, the self‐cyclization occurs.
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Multiple solid-phase synthesis of hydantoins and thiohydantoins

Molecular Diversity, 1997
A novel general protocol for the construction of hydantoins and thiohydantoins on a solid support has been developed. Using this novel methodology, the synthesis of a diverse 96-compound library has been achieved. Resin-bound dipeptides are cyclised via the formation of an intermediate isocyanate or isothiocyanate on resin as the key step in the ...
G, Bhalay, D, Cowell, N D, Hone, M, Scobie, A D, Baxter   +4 more
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Improved chromatographic identification of coloured amino acid thiohydantoins

Journal of Chromatography A, 1977
A new N-terminal reagent for peptides and proteins, 4-N,N-dimethylamino-naphthylazobenzene-4'-isothiocyanate, is described which gives purple thiohydantoin derivatives; chromatographic separation of 24 amino acid thiohydantoins is reported.
J Y, Chang, E H, Creaser
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Thiohydantoins: synthetic strategies and chemical reactions

Journal of Sulfur Chemistry, 2012
The chemistry of thiohydantoins has gained increased interest in both synthetic organic chemistry and biological fields. Many of these compounds exhibit considerable biological activities in various fields. This review covers the literature regarding the synthesis, reactions, and applications of such compounds.
Mohamed A. Metwally, Ehab Abdel-Latif
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Thiohydantoins. I. The Preparation of Some 2-Thiohydantoins from Amino Acids and Acylamino Acids

Australian Journal of Scientific Research Series A: Physical Sciences, 1952
A reinvestigation of the stepwise degradation of peptides and proteins by the Schlack and Kumpf (1926) procedure, which involves conversion of the terminal carboxyl residue to a 5-substituted-2-thiohydantoin; has been undertaken. The following amino acids or their aoetyl derivatives have been converted by warming with acetic anhydride and ammonium ...
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Microwave-assisted traceless synthesis of thiohydantoin

Tetrahedron Letters, 2003
Abstract An efficient, microwave-assisted method for the liquid-phase combinatorial synthesis of 3,5-disubstituted-thiohydantoin has been developed. Fmoc-protected amino acids were coupled with HO-PEG-OH and after deprotection, reacted with various isothiocyanates in microwave cavity.
Mei-Jung Lin, Chung-Ming Sun
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Thiohydantoins. III. Anhydride Intermediates in the Formation of 1-Acyl-2-thiohydantoins from Acylamino Acids

Australian Journal of Scientific Research Series A: Physical Sciences, 1952
Linear anhydrides are formed by the action of acetic anhydride on p-toluene-sulphonylglycine and carbobenzyloxy-glycine, -phenylalanine, and -β-alanine. The anhydrides from the first two acids yield the corresponding 2-thiohydantoin with ammonium thiocyanate in acetic acid. Other methods for the preparation of l-p-toluenesulphonylglycine anhydride, and
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Bis‐Thiohydantoine

Justus Liebigs Annalen der Chemie, 1913
G. Frerichs, H. Höller
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Hydantoine, thiohydantoine, glykocyamidine—XXXIII

Tetrahedron, 1971
J. Fetter, J. Nyitrai, K. Lempert
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Thiohydantoins

2023
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