Results 41 to 50 of about 465 (157)
1,2‐Diaza‐1,3‐butadienes, also called azoalkenes, have received considerable attention as key synthons for constructing various heterocyclic scaffolds. This minireview summarizes the contribution of our group in this field over the period from 2009 to the present, focusing on the role of the azoene building block in forming the heterocyclic structures.
Lucia De Crescentini +4 more
wiley +1 more source
HYDANTOINS: SYNTHESIS OF 5-THIOHYDANTOINS. [NINETEENTH PAPER.] [PDF]
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Johnson, Treat B., Chernoff, Lewis H.
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Chiral Quaternary Ammonium Salt‐Catalyzed Enantioselective Addition Reactions of Hydantoins
Abstract We herein report a protocol for the asymmetric 1,4‐addition of hydantoins to various Michael acceptors by utilizing Cinchona alkaloid‐based chiral quaternary ammonium salt catalysts. Various products were obtained with moderate to good enantioselectivities and accompanying computational investigations helped to identify key interactions ...
Katharina Röser +5 more
wiley +1 more source
Dopaminergic neuronal death via necroptosis in Parkinson's disease: A review of the literature
We reviewed the current literature on the potential role of necroptosis, a recently characterized regulated cell death mechanism, in Parkinson's disease (PD) pathogenesis. We summarized findings from studies on necroptosis in PD preclinical models and PD human tissue samples, discussing how manipulating necroptosis might open a novel therapeutic ...
Maria Regoni +2 more
wiley +1 more source
Abstract Immunoisolation of pancreatic islets in alginate microcapsules allows for transplantation in the absence of immunosuppression but graft survival time is still limited. This limited graft survival is caused by a combination of tissue responses to the encapsulating biomaterial and islets. A significant loss of islet cells occurs in the immediate
Alexandra M. Smink +4 more
wiley +1 more source
The exposure systems of glycidol‐related chemicals on the formation of glycidol‐hemoglobin adducts diHOPrVal were compared. DiHOPrVal formation was observed using several chemicals other than glycidol with different behaviors in vitro and in vivo. However, in both cases, the amount of diHOPrVal produced was very small compared with glycidol. This study
Yuko Shimamura +4 more
wiley +1 more source
This study investigates a series of zingerone 2-thiohydantoins for anticancer activity towards human breast adenocarcinoma and explores possible mechanisms of anticancer action.
Petar Stanić +6 more
doaj +1 more source
Department of Chemistry, Sambalpur University, Sambalpur and Department of Chemistry, G. M. College, Sambalpur. Manuscript received 27 May 1972; accepted 4 July 1975. Several substituted benzothiazolyl thiohydantoias (I), their arylideae derivatives (II) and dibromo compounds (W) have been synthesised.
M. BEHERA, P. N. DHAL, A. NAYAK
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A FLUORIMETRIC ASSAY FOR MINUTE AMOUNTS OF SOME THIOHYDANTOINS
Abstract A fluorimetric assay sensitive to μg. quantities of certain thiohydantoins has been devised using dichloroquinone chloroimide as a fluorescence reagent. The nature of the buffer used is critical. Satisfactory results have been obtained for recoveries from urine, spinal fluid and plasma.
M E, AUERBACH, E, ANGELL
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