Results 41 to 50 of about 769 (187)
Acta Chimica Slovenica, 2015 Synthesis and characterization of new Pt(II) complexes of cyclohexanespiro-5-(2-thiohydantoin) (L1) and cycloheptanespiro-5-(2-thiohydantoin) (L2) are discussed. The new complexes are studied by elemental analysis, IR, ATR FTIR spectroscopy.
Petja E. Marinova +3 more
doaj +1 more source
Food Frontiers, Volume 7, Issue 3, May 2026.ABSTRACT Ergothioneine (EGT), a natural thiol derivative, has gained attention as a geroprotective nutraceutical. Preclinical research shows EGT scavenges free radicals, maintains mitochondrial integrity, slows telomere erosion, and regulates proteostasis via autophagy and senescent cell clearance.
Tian‐Tian Tian +3 more
wiley +1 more source
On Formation of Thiohydantoins from Amino Acids under Acylation Conditions
, 2016 Reactions of glycine, alanine, and phenylalanine with acetic anhydride and ammonium thiocyanate give the 1-acetyl-2-thiohydantoins 2a−c.
Samuel Reyes (2356765) +1 more
core +1 more source
HYDANTOINS: THE HISTORY OF 2-THIOHYDANTOIN. XXII. [PDF]
Journal of the American Chemical Society, 1913 n ...
openaire +2 more sources
Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds
ChemMedChem, Volume 21, Issue 2, January 2026.Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley +1 more source
Illuminating Tau Aggregates: Multiscale Approaches for Detection, Imaging, and Understanding
Aggregate, Volume 6, Issue 10, October 2025.This review presents recent advances in molecular imaging of tauopathies, focusing on tau aggregation mechanisms, structural polymorphism, and imaging strategies. It highlights the development of tau‐selective fluorescent probes and PET tracers and explores emerging techniques such as cryo‐EM and super‐resolution imaging, offering a multiscale ...
Kaustubh R. Bhuskute +2 more
wiley +1 more source
Investigation of Novel Isatinylhydantoin Derivatives as Potential Anti‐Kinetoplastid Agents
ChemMedChem, Volume 20, Issue 1, January 2, 2025.A series of isatinylhydantoin derivatives were synthesized and investigated for antileishmanial and antitrypanosomal activities in vitro and in vivo. The derivative 5 was identified with higher leishmanicidal activity than the clinical drug amphotericin B while 4b was uncovered as in vitro trypanocidal hit against T. congolense parasite.
Keamogetswe Sechoaro +5 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 27, Issue 44, November 25, 2024.1,2‐Diaza‐1,3‐butadienes, also called azoalkenes, have received considerable attention as key synthons for constructing various heterocyclic scaffolds. This minireview summarizes the contribution of our group in this field over the period from 2009 to the present, focusing on the role of the azoene building block in forming the heterocyclic structures.
Lucia De Crescentini +4 more
wiley +1 more source
HYDANTOINS: THE SYNTHESIS OF 2-THIOHYDANTOIN. [SEVENTH PAPER.] [PDF]
Journal of the American Chemical Society, 1911 n ...
Johnson, Treat B., Nicolet, Ben H.
openaire +1 more source
ChemistrySelect, Volume 9, Issue 11, March 18, 2024.A synthetic approach to the synthesis of novel heterobivalent compounds containing urea and 5‐arylthiohydantoin groups was developed for the preparation of a mixture‐based library. Through the screening and deconvolution of the library, six hits with βC branched residues at R1 and imidazyl residue at R3 were identified exhibiting moderate inhibitory ...
Chelsi Whitely +2 more
wiley +1 more source