Results 31 to 40 of about 465 (157)

Reactivity of 2-Thiohydantoins Towards Various Electrophilic Reagents: Applications to the Synthesis of New 2-Ylidene-3,5-dihydro-4H-imidazol-4-ones.

open access: yesMolecules, 2004
A new route to 5-(imidazolidin-2-ylidene)-2-methylsulfanyl-3,5-dihydro-imidazol-4-ones 4a-c using ketene dithioacetal intermediates 3a-c is described.
Jean Pierre Bazureau   +2 more
doaj   +1 more source

HYDANTOINS: THE HISTORY OF 2-THIOHYDANTOIN. XXII. [PDF]

open access: yesJournal of the American Chemical Society, 1913
n ...
openaire   +2 more sources

Acrylamide Exposure, Biological Aging Acceleration, With Ankle‐Brachial Index and Peripheral Artery Disease: Exploring Association, Interaction, and Underlying Mechanism

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
We provided the first evidence that exposure of general adults to ACR was related to ABI decrement and PAD odds increment, which might be partly associated with accelerated biological aging. Lipid and atherosclerosis pathway may be suggestively implicated in the mechanism underlying these associations.
Feifei Wang   +11 more
wiley   +1 more source

Enantiodifferentiation of α-Arylacetic Acid and Thiohydantoin Derivatives by NMR Using Thiourea-Based Chiral Solvating Agents

open access: yesMolecules
Two thiourea-based chiral solvating agents (CSAs), S-1 and S-2, were evaluated for the enantiomeric discrimination of representative α-arylacetic acids by 1H NMR spectroscopy in the presence of DMAP. Enantiomeric discrimination was assessed by monitoring
Sule Erol Gunal
doaj   +1 more source

New platinum(II) complexes of cycloalkanespiro-5-(2-thiohydantoins). Synthesis and quantum chemical investigation

open access: yesActa Chimica Slovenica, 2015
Synthesis and characterization of new Pt(II) complexes of cyclohexanespiro-5-(2-thiohydantoin)  (L1) and cycloheptanespiro-5-(2-thiohydantoin) (L2) are discussed. The new complexes are studied by elemental analysis, IR, ATR FTIR spectroscopy.
Petja E. Marinova   +3 more
doaj   +1 more source

Dietary Ergothioneine as a Novel Anti‐Aging Nutraceutical: Mechanisms, Bioavailability, and Future Perspectives

open access: yesFood Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Ergothioneine (EGT), a natural thiol derivative, has gained attention as a geroprotective nutraceutical. Preclinical research shows EGT scavenges free radicals, maintains mitochondrial integrity, slows telomere erosion, and regulates proteostasis via autophagy and senescent cell clearance.
Tian‐Tian Tian   +3 more
wiley   +1 more source

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

open access: yesChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

Heterocyclic systems containing S/N regioselective nucleophilic competition: facile synthesis, antitubercular and antimicrobial activity of thiohydantoins and iminothiazolidinones containing the benzo[b]thiophene moiety [PDF]

open access: yesJournal of the Serbian Chemical Society, 2005
The required compounds N-aryl-N'-(3-chloro-2-benzo[b]thenoyl)–thioureas 1a–k were prepared by condensing 3-chloro-2-benzo[b]thenoyl chloride with different arylamines using ammonium thiocyanate, which in turn when treated with chloroacetic acid, yielded ...
H. S. JOSHI   +2 more
doaj  

Illuminating Tau Aggregates: Multiscale Approaches for Detection, Imaging, and Understanding

open access: yesAggregate, Volume 6, Issue 10, October 2025.
This review presents recent advances in molecular imaging of tauopathies, focusing on tau aggregation mechanisms, structural polymorphism, and imaging strategies. It highlights the development of tau‐selective fluorescent probes and PET tracers and explores emerging techniques such as cryo‐EM and super‐resolution imaging, offering a multiscale ...
Kaustubh R. Bhuskute   +2 more
wiley   +1 more source

Investigation of Novel Isatinylhydantoin Derivatives as Potential Anti‐Kinetoplastid Agents

open access: yesChemMedChem, Volume 20, Issue 1, January 2, 2025.
A series of isatinylhydantoin derivatives were synthesized and investigated for antileishmanial and antitrypanosomal activities in vitro and in vivo. The derivative 5 was identified with higher leishmanicidal activity than the clinical drug amphotericin B while 4b was uncovered as in vitro trypanocidal hit against T. congolense parasite.
Keamogetswe Sechoaro   +5 more
wiley   +1 more source

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