Results 11 to 20 of about 697 (188)
A Simple Synthesis of 2-Thiohydantoins [PDF]
Molecules, 2006 2-Thiohydantoin derivatives are produced by heating a mixture of thiourea and an α-amino acid. The method described offers the advantages of simplicity, low cost, easy work-up and scalability.
Yulu Zhang +2 more
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Molecules, 2018 The preparation of 5-methylene-thiohydantoins using solid-phase synthesis is reported in this paper. After sulfonylation of immobilized Ser (t-Bu)-OH with 4-nitrobenzenesulfonyl chloride followed by alkylation with various bromoketones, the 4-Nos group ...
Petra Králová +3 more
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Molecules, 1999 The title 3-amino-2-thiohydantoins 3 has been prepared in very good yields by the reaction of alkyl isothiocynatocarboxylates 1 with hydrazine hydrate.The synthesis of starting isothiocyanates as well as spectral data of 3-aminothiohydantoins and alkyl ...
Martin Kovac +2 more
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Facile regiodivergent synthesis of spiro pyrrole-substituted pseudothiohydantoins and thiohydantoins via reaction of [e]-fused 1H-pyrrole-2,3-diones with thiourea [PDF]
Beilstein Journal of Organic Chemistry, 2019 A highly divergent synthesis of regioisomeric thiohydantoins and pseudothiohydantoins spiro-fused to a pharmacologically valuable pyrrole-2-one fragment involving the reaction of [e]-fused 1H-pyrrole-2,3-diones with thioureas was developed.
Aleksandr I. Kobelev +5 more
doaj +2 more sources
A FLUORIMETRIC ASSAY FOR MINUTE AMOUNTS OF SOME THIOHYDANTOINS
Journal of Pharmacy and Pharmacology, 1958 A fluorimetric assay sensitive to μg. quantities of certain thiohydantoins has been devised using dichloroquinone chloroimide as a fluorescence reagent. The nature of the buffer used is critical.
Eleanor Angell, M E Auerbach
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Green Chemistry Letters and Reviews, 2016 A simple and eco-friendly method for the synthesis of novel imidazo[2,1-b][1,3]thiazin derivatives has been developed via the one-pot, three-component and solvent-free reaction of thiohydantoins, aromatic aldehyde and 5,5-dimethylcyclohexane-1,3-dione in
Mohammad Mehdi Ghanbari
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Heterocyclic systems containing S/N regioselective nucleophilic competition: facile synthesis, antitubercular and antimicrobial activity of thiohydantoins and iminothiazolidinones containing the benzo[b]thiophene moiety [PDF]
Journal of the Serbian Chemical Society, 2005 The required compounds N-aryl-N'-(3-chloro-2-benzo[b]thenoyl)thioureas 1ak were prepared by condensing 3-chloro-2-benzo[b]thenoyl chloride with different arylamines using ammonium thiocyanate, which in turn when treated with chloroacetic acid, yielded ...
H. S. JOSHI +2 more
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Hydantoins, thiohydantoins, glycocyamidines—36
Tetrahedron, 1973 Abstract In contrast to the α-chloroamides 1a-c which, when reacted with potassium N-cyanoanilide, furnish anomalous substitution products ( 2a-c ), the related nitrile and ester yields normal substitution products ( 3a and b ) under the same conditions.
K. Lempert, Gy. Simig, J. Tamás
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[4+2]-Cycloaddition to 5-Methylidene-Hydantoins and 5-Methylidene-2-Thiohydantoins in the Synthesis of Spiro-2-Chalcogenimidazolones. [PDF]
Int J Mol Sci, 2023 Novel hydantion and thiohydantoin-based spiro-compounds were prepared via theDiels–Alder reactions between 5-methylidene-hydantoins or 5-methylidene-2-thiohydantoins and 1,3-dienes (cyclopentadiene, cyclohexadiene, 2,3-dimethylbutadiene, isoprene).
Shybanov DE +8 more
europepmc +2 more sources
Atroposelective Synthesis of Axially Chiral Thiohydantoin Derivatives
The Journal of Organic Chemistry, 2016 Nonracemic axially chiral thiohydantoins were synthesized atroposelectively by the reaction of o-aryl isothiocyanates with amino acid ester salts in the presence of triethylamine (TEA).
Sevgi Sarigul (2855297) +1 more
core +3 more sources