Results 51 to 60 of about 769 (187)
, 1973 Department of Chemistry, G. M. College, Sambalpur and P. G. Department of Chemistry, Sambalpur University, Burla, Sambalpur Manuscript received 6 April 1972; revised 16 March 1973; accepted 21 June 1973 Some new heterocyclic substituted thiohydantoins(
P. N. DHAL +3 more
core +1 more source
Chiral Quaternary Ammonium Salt‐Catalyzed Enantioselective Addition Reactions of Hydantoins
Helvetica Chimica Acta, Volume 107, Issue 3, March 2024.Abstract We herein report a protocol for the asymmetric 1,4‐addition of hydantoins to various Michael acceptors by utilizing Cinchona alkaloid‐based chiral quaternary ammonium salt catalysts. Various products were obtained with moderate to good enantioselectivities and accompanying computational investigations helped to identify key interactions ...
Katharina Röser +5 more
wiley +1 more source
Synthesis of 3-substituted 5-arylidene-1-methyl-2-Thiohydantoins under microwave irradiation
, 2002 A mono-modal microwave oven was used to expedite the synthesis of small libraries of 3-substituted 1-methyl-2-thiohydantoins and 3-substituted 5-arylidene-1-methyl-2-thiohydantoins.
Nielsen, John, Khodair, Ahmed I.
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Dopaminergic neuronal death via necroptosis in Parkinson's disease: A review of the literature
European Journal of Neuroscience, Volume 59, Issue 6, Page 1079-1098, March 2024.We reviewed the current literature on the potential role of necroptosis, a recently characterized regulated cell death mechanism, in Parkinson's disease (PD) pathogenesis. We summarized findings from studies on necroptosis in PD preclinical models and PD human tissue samples, discussing how manipulating necroptosis might open a novel therapeutic ...
Maria Regoni +2 more
wiley +1 more source
Fluorous parallel synthesis of a hydantoin/thiohydantoin library [PDF]
Molecular Diversity, 2005 Fluorous tagging strategy is applied to solution-phase parallel synthesis of a library containing hydantoin and thiohydantoin analogs. Two perfluoroalkyl (Rf)-tagged alpha-amino esters each react with six aromatic aldehydes under reductive amination conditions. Twelve amino esters then each react with 10 isocyanates and isothiocyanates in parallel. The
Yimin, Lu, Wei, Zhang
openaire +2 more sources
Journal of Biomedical Materials Research Part A, Volume 112, Issue 2, Page 288-295, February 2024.Abstract Immunoisolation of pancreatic islets in alginate microcapsules allows for transplantation in the absence of immunosuppression but graft survival time is still limited. This limited graft survival is caused by a combination of tissue responses to the encapsulating biomaterial and islets. A significant loss of islet cells occurs in the immediate
Alexandra M. Smink +4 more
wiley +1 more source
Food Science &Nutrition, Volume 12, Issue 1, Page 471-480, January 2024.The exposure systems of glycidol‐related chemicals on the formation of glycidol‐hemoglobin adducts diHOPrVal were compared. DiHOPrVal formation was observed using several chemicals other than glycidol with different behaviors in vitro and in vivo. However, in both cases, the amount of diHOPrVal produced was very small compared with glycidol. This study
Yuko Shimamura +4 more
wiley +1 more source
Three-component diastereoselective cascade synthesis of thiohydantoins
A new three-component cascade reaction for the synthesis of thiohydantoins is reported. The reaction between ?-amino esters, nitrostyrenes, and aromatic isothiocyanates is efficiently promoted by organic bases to afford highly substituted thiohydantoins ...
Meazza, Marta +4 more
core +1 more source
, 2011 Highly substituted bicyclic thiohydantoins fused to pyrrolidines were prepared from aminocarbo-N-thioylpyrrolidines derived from alpha-amino acid esters via imine azomethine ylide 1,3-dipolar cycloadditions and subsequent reaction with ...
Ronald Grigg +7 more
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Formation of amino acid derived 2-thiohydantoins - An experimental and theoretical study [PDF]
, 2019 Hydantoins and thiohydantoins derived from amino acids are an interesting subset of compounds that have a wide range of chemical and biological properties.
Milenkovic, Dejan +9 more
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