Results 51 to 60 of about 697 (188)

Formation of amino acid derived 2-thiohydantoins - An experimental and theoretical study [PDF]

, 2019
Hydantoins and thiohydantoins derived from amino acids are an interesting subset of compounds that have a wide range of chemical and biological properties.
Milenkovic, Dejan, Zivkovic, Marija, Zoran Markovic, Šmit, Biljana, Markovic, Zoran, Petar Stanic, Stanić, Petar, Dejan Milenkovic, Biljana Smit, Marija Zivkovic   +9 more
core   +1 more source

1,2‐Diaza‐1,3‐Dienes as a Multifaceted Synthons for the Synthesis of Heterocycles: A Fifteen‐Years Update

European Journal of Organic Chemistry, Volume 27, Issue 44, November 25, 2024.
1,2‐Diaza‐1,3‐butadienes, also called azoalkenes, have received considerable attention as key synthons for constructing various heterocyclic scaffolds. This minireview summarizes the contribution of our group in this field over the period from 2009 to the present, focusing on the role of the azoene building block in forming the heterocyclic structures.
Lucia De Crescentini, Giacomo Mari, Stefania Santeusanio, Gianfranco Favi, Fabio Mantellini   +4 more
wiley   +1 more source

Polysubstituted Fused Ring Bicyclic Thiohydantoins from Aminocarbo-N-thioylpyrrolidines Derived from Azomethine Ylide 1,3-Dipolar Cycloadditions

, 2011
Highly substituted bicyclic thiohydantoins fused to pyrrolidines were prepared from aminocarbo-N-thioylpyrrolidines derived from alpha-amino acid esters via imine azomethine ylide 1,3-dipolar cycloadditions and subsequent reaction with ...
Ronald Grigg, Yahya Nural, Grigg, Ronald, H. Ali Döndaş, Ertan Şahin, ŞAHİN, Ertan, NURAL, YAHYA, DÖNDAŞ, HACI ALİ   +7 more
core   +1 more source

HYDANTOINS: SYNTHESIS OF 5-THIOHYDANTOINS. [NINETEENTH PAPER.] [PDF]

Journal of the American Chemical Society, 1912
n ...
Johnson, Treat B., Chernoff, Lewis H.
openaire   +2 more sources

Chiral Quaternary Ammonium Salt‐Catalyzed Enantioselective Addition Reactions of Hydantoins

Helvetica Chimica Acta, Volume 107, Issue 3, March 2024.
Abstract We herein report a protocol for the asymmetric 1,4‐addition of hydantoins to various Michael acceptors by utilizing Cinchona alkaloid‐based chiral quaternary ammonium salt catalysts. Various products were obtained with moderate to good enantioselectivities and accompanying computational investigations helped to identify key interactions ...
Katharina Röser, Lucas Prameshuber, Sajid Jahangir, Sharath Chandra Mallojjala, Jennifer S. Hirschi, Mario Waser   +5 more
wiley   +1 more source

3-Cyclohexyl-5-Arylidene-2-Thiohydantoins as Possible Anticonvulsants

, 1981
Department of Chemistry, University of Lucknow, Lucknow-226 007 Manuscript received 20 December 1980, revised 19 October 1981, accepted 6 November 1981 Some new 3-cyclohexyl-5-arylidene-2-thiohydantoins were synthesised by the condensation of 3 ...
G. C. SRIVASTAVA, M. I. HUSAIN
core   +1 more source

Dopaminergic neuronal death via necroptosis in Parkinson's disease: A review of the literature

European Journal of Neuroscience, Volume 59, Issue 6, Page 1079-1098, March 2024.
We reviewed the current literature on the potential role of necroptosis, a recently characterized regulated cell death mechanism, in Parkinson's disease (PD) pathogenesis. We summarized findings from studies on necroptosis in PD preclinical models and PD human tissue samples, discussing how manipulating necroptosis might open a novel therapeutic ...
Maria Regoni, Flavia Valtorta, Jenny Sassone   +2 more
wiley   +1 more source

Necrostatin‐1 releasing nanoparticles: In vitro and in vivo efficacy for supporting immunoisolated islet transplantation outcomes

Journal of Biomedical Materials Research Part A, Volume 112, Issue 2, Page 288-295, February 2024.
Abstract Immunoisolation of pancreatic islets in alginate microcapsules allows for transplantation in the absence of immunosuppression but graft survival time is still limited. This limited graft survival is caused by a combination of tissue responses to the encapsulating biomaterial and islets. A significant loss of islet cells occurs in the immediate
Alexandra M. Smink, Juan D. Medina, Bart J. de Haan, Andrés J. García, Paul de Vos   +4 more
wiley   +1 more source

Fluorous parallel synthesis of a hydantoin/thiohydantoin library [PDF]

Molecular Diversity, 2005
Fluorous tagging strategy is applied to solution-phase parallel synthesis of a library containing hydantoin and thiohydantoin analogs. Two perfluoroalkyl (Rf)-tagged alpha-amino esters each react with six aromatic aldehydes under reductive amination conditions. Twelve amino esters then each react with 10 isocyanates and isothiocyanates in parallel. The
Yimin, Lu, Wei, Zhang
openaire   +2 more sources

A comparison of the exposure system of glycidol‐related chemicals on the formation of glycidol‐hemoglobin adducts

Food Science &Nutrition, Volume 12, Issue 1, Page 471-480, January 2024.
The exposure systems of glycidol‐related chemicals on the formation of glycidol‐hemoglobin adducts diHOPrVal were compared. DiHOPrVal formation was observed using several chemicals other than glycidol with different behaviors in vitro and in vivo. However, in both cases, the amount of diHOPrVal produced was very small compared with glycidol. This study
Yuko Shimamura, Yuri Wada, Moeka Tashiro, Hiroshi Honda, Shuichi Masuda   +4 more
wiley   +1 more source