Results 201 to 210 of about 221,664 (312)

Cell surface thiol-disulfide regulation in cancer: Mechanisms, implications, and theranostic strategies. [PDF]

Redox Biol
Lühle J, Seeberger PH, Moscovitz O.
europepmc   +1 more source

A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun, Jing Zhang, Chenqing Liu, Jing Lou, Sihui Wang, Xiangtian Ji, Xiaofang Zhao, Shirui Xu, Jingyu Feng, Bin Liu, Chao Chang, Qinggang Ge, Jun Yang   +12 more
wiley   +1 more source

Designing soft materials through synthetic morphogenesis. [PDF]

Nat Commun
Bortnikov EO, Paikar A, Zhigileva EA, Fomitskaya P, Ariel N, Diskin-Posner Y, Avram L, Sui XM, Skorb EV, Sütő I, Horváth D, Tóth Á, Semenov SN.   +12 more
europepmc   +1 more source

The Enzymic Oxidation of Thiols [PDF]

Biochemical Journal, 1966
openaire   +2 more sources

Pathogen‐Centric Activation of an Azoreductase‐Responsive Antibody‐Antibiotic Conjugate for the Targeted Eradication of MRSA

Advanced Science, EarlyView.
A pathogen‐centric antibody‐antibiotic conjugate (AZO‐AAC) releases antibiotics via bacterial azoreductase, independent of host‐lysosomal function. This mechanism achieves nanomolar eradication of both planktonic and intracellular methicillin‐resistant Staphylococcus aureus (MRSA).
Qi Cheng, Lianqi Liu, Chenghua Liu, Fei Xie, Jingwen Dong, Xiaoyu Qin, Shunxiang Huang, Xian Li, Xingyuan Kou, Hongbin Deng, Jiannan Feng, Wu Zhong, Dian Xiao, Xinbo Zhou   +13 more
wiley   +1 more source

Thiol-Functionalized Succinoglycan via Cysteine Grafting: Enhanced Rheological Properties and Antioxidant Activity. [PDF]

Polymers (Basel)
Jeon S, Kim K, Oh E, Jin H, Jung S.
europepmc   +1 more source

Spike‐Embedded Nanocatalysts via Metal‐Directed Carbonization for Highly Efficient and Robust Semi‐Hydrogenation

Advanced Science, EarlyView.
A metal‐directed carbonization strategy transforms hierarchical organic microspheres into spiky carbon catalysts with Pd nanoparticles embedded at the tips. This approach resolves the activity‐stability trade‐off, achieving exceptional poison resistance in semi‐hydrogenations, offering a versatile, scalable platform for designing high‐performance ...
Yintao Li, Yang Sun, Minghang Li, Wenxuan Zhang, Zhengtao Li, Yihao Ni, Yao Zhang, Yong Wang, Samuel S. Veroneau, Pengfei Ji   +9 more
wiley   +1 more source

Implementation and Validation of Titratable Cysteine in GROMACS-Based Constant-pH Molecular Dynamics. [PDF]

J Chem Theory Comput
Capelli R.
europepmc   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

A (poly)Pro tip for preserving native disulfide connectivity during thiol-maleimide bioconjugation of disulfide-rich peptides. [PDF]

Chem Sci
Azzoug L, Novak A, Meudal H, Madinier JB, Charpentier S, Loth K, Morisset-Lopez S, Pifferi C, Aucagne V.   +8 more
europepmc   +1 more source