Results 11 to 20 of about 103,347 (189)

Transfection efficiency of chitosan and thiolated chitosan in retinal pigment epithelium cells: A comparative study

open access: yesJournal of Pharmacy and Bioallied Sciences, 2013
Objective: Gene therapy relies on efficient vector for a therapeutic effect. Efficient non-viral vectors are sought as an alternative to viral vectors. Chitosan, a cationic polymer, has been studied for its gene delivery potential.
Ana V Oliveira   +4 more
doaj   +5 more sources

Injectable Hydrogels Composed of Thiolated Chitosan, Silk Fibroin, and Gallium-Doped Bioactive Glass Nanoparticles for Bone Regeneration and Osteosarcoma Suppression [PDF]

open access: yesInternational Journal of Nanomedicine
Jiaoyan Liu,1,2 Ronghua Tan,1 Congcong Wang,1 Guimin Li,2 Hong Zheng,2 Ying Wan1 1College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, People’s Republic of China; 2School of Basic Medical Sciences, Anhui ...
Liu J   +5 more
doaj   +4 more sources

Thiolated Chitosan Microneedle Patch of Levosulpiride from Fabrication, Characterization to Bioavailability Enhancement Approach [PDF]

open access: yesPolymers, 2022
In this study, a first attempt has been made to deliver levosulpiride transdermally through a thiolated chitosan microneedle patch (TC-MNP). Levosulpiride is slowly and weakly absorbed from the gastrointestinal tract with an oral bioavailability of less ...
Aamir Jalil   +2 more
exaly   +3 more sources

Synthesis and Characterization of New Thiolated Chitosan Nanoparticles Obtained by Ionic Gelation Method

open access: yesInternational Journal of Polymer Science, 2015
We derivatized low molecular weight chitosan (LMWC) with 3-mercaptopropanoic acid (3-MPA) by a coupling reaction. The chemical modification of LMWC was characterized by Fourier transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance, 1HNMR.
Reynaldo Esquivel   +4 more
doaj   +2 more sources

Applications of chitosan derivatives as adjuvants for nanoparticle‐based vaccines: A comprehensive review [PDF]

open access: yesSmart Molecules, Volume 4, Issue 3, September 2026.
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Sayantani Dasgupta   +8 more
wiley   +2 more sources

S-Protected Thiolated Chitosan versus Thiolated Chitosan as Cell Adhesive Biomaterials for Tissue Engineering. [PDF]

open access: yesACS Appl Mater Interfaces, 2023
Chitosan (Ch) and different Ch derivatives have been applied in tissue engineering (TE) because of their biocompatibility, favored mechanical properties, and cost-effectiveness. Most of them, however, lack cell adhesive properties that are crucial for TE.
Le-Vinh B   +4 more
europepmc   +4 more sources

Formulation for the Targeted Delivery of a Vaccine Strain of Oncolytic Measles Virus (OMV) in Hyaluronic Acid Coated Thiolated Chitosan as a Green Nanoformulation for the Treatment of Prostate Cancer: A Viro-Immunotherapeutic Approach

open access: yesInternational Journal of Nanomedicine, 2023
Faiza Naseer,1,2 Tahir Ahmad,1 Kousain Kousar,1 Salik Kakar,3 Rabia Gul,2 Sadia Anjum,4 Usman Shareef2 1Industrial Biotechnology, Atta-ur-Rehman School of Applied Biosciences, National University of Science and Technology, Islamabad, Pakistan; 2Shifa ...
Naseer F   +6 more
doaj   +2 more sources

Preparation and in vitro evaluation of thiolated chitosan microparticles

open access: yesJournal of Microencapsulation, 2005
The objective of this study was to prepare a microparticulate drug delivery system being based on a new thiomer, namely a chitosan 2-iminothiolane conjugate (chitosan-TBA conjugate).
MACULOTTI, KATIA   +5 more
core   +4 more sources

Anticancer Analysis of CD44 Targeted Cyclosporine Loaded Thiolated Chitosan Nanoformulations for Sustained Release in Triple-Negative Breast Cancer [Retraction] [PDF]

open access: yesInternational Journal of Nanomedicine
Abduh MS. Int J Nanomedicine. 2023;18:5713–5732. We, the Editor and Publisher of the journal International Journal of Nanomedicine are retracting the published article.
Abduh MS
doaj   +2 more sources

Formulation for the Targeted Delivery of a Vaccine Strain of Oncolytic Measles Virus (OMV) in Hyaluronic Acid Coated Thiolated Chitosan as a Green Nanoformulation for the Treatment of Prostate Cancer: A Viro-Immunotherapeutic Approach [Retraction] [PDF]

open access: yesInternational Journal of Nanomedicine
Naseer F, Ahmad T, Kousar K, et al. Int J Nanomedicine. 2023;18:185–205. We, the Editor and Publisher of the journal International Journal of Nanomedicine are retracting the published article.
Naseer F   +6 more
doaj   +2 more sources

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