Objective: Gene therapy relies on efficient vector for a therapeutic effect. Efficient non-viral vectors are sought as an alternative to viral vectors. Chitosan, a cationic polymer, has been studied for its gene delivery potential.
Ana V Oliveira +4 more
doaj +5 more sources
Injectable Hydrogels Composed of Thiolated Chitosan, Silk Fibroin, and Gallium-Doped Bioactive Glass Nanoparticles for Bone Regeneration and Osteosarcoma Suppression [PDF]
Jiaoyan Liu,1,2 Ronghua Tan,1 Congcong Wang,1 Guimin Li,2 Hong Zheng,2 Ying Wan1 1College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, People’s Republic of China; 2School of Basic Medical Sciences, Anhui ...
Liu J +5 more
doaj +4 more sources
Thiolated Chitosan Microneedle Patch of Levosulpiride from Fabrication, Characterization to Bioavailability Enhancement Approach [PDF]
In this study, a first attempt has been made to deliver levosulpiride transdermally through a thiolated chitosan microneedle patch (TC-MNP). Levosulpiride is slowly and weakly absorbed from the gastrointestinal tract with an oral bioavailability of less ...
Aamir Jalil +2 more
exaly +3 more sources
We derivatized low molecular weight chitosan (LMWC) with 3-mercaptopropanoic acid (3-MPA) by a coupling reaction. The chemical modification of LMWC was characterized by Fourier transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance, 1HNMR.
Reynaldo Esquivel +4 more
doaj +2 more sources
Applications of chitosan derivatives as adjuvants for nanoparticle‐based vaccines: A comprehensive review [PDF]
This review highlights how chitosan derivatives enhance nanoparticle‐based vaccines through superior stability, mucoadhesion, and immune modulation. By triggering robust mucosal, humoral, and cellular responses, these biocompatible polymers serve as a transformative platform for next‐generation immunotherapeutics and safe and effective vaccine delivery
Sayantani Dasgupta +8 more
wiley +2 more sources
S-Protected Thiolated Chitosan versus Thiolated Chitosan as Cell Adhesive Biomaterials for Tissue Engineering. [PDF]
Chitosan (Ch) and different Ch derivatives have been applied in tissue engineering (TE) because of their biocompatibility, favored mechanical properties, and cost-effectiveness. Most of them, however, lack cell adhesive properties that are crucial for TE.
Le-Vinh B +4 more
europepmc +4 more sources
Faiza Naseer,1,2 Tahir Ahmad,1 Kousain Kousar,1 Salik Kakar,3 Rabia Gul,2 Sadia Anjum,4 Usman Shareef2 1Industrial Biotechnology, Atta-ur-Rehman School of Applied Biosciences, National University of Science and Technology, Islamabad, Pakistan; 2Shifa ...
Naseer F +6 more
doaj +2 more sources
Preparation and in vitro evaluation of thiolated chitosan microparticles
The objective of this study was to prepare a microparticulate drug delivery system being based on a new thiomer, namely a chitosan 2-iminothiolane conjugate (chitosan-TBA conjugate).
MACULOTTI, KATIA +5 more
core +4 more sources
Anticancer Analysis of CD44 Targeted Cyclosporine Loaded Thiolated Chitosan Nanoformulations for Sustained Release in Triple-Negative Breast Cancer [Retraction] [PDF]
Abduh MS. Int J Nanomedicine. 2023;18:5713–5732. We, the Editor and Publisher of the journal International Journal of Nanomedicine are retracting the published article.
Abduh MS
doaj +2 more sources
Formulation for the Targeted Delivery of a Vaccine Strain of Oncolytic Measles Virus (OMV) in Hyaluronic Acid Coated Thiolated Chitosan as a Green Nanoformulation for the Treatment of Prostate Cancer: A Viro-Immunotherapeutic Approach [Retraction] [PDF]
Naseer F, Ahmad T, Kousar K, et al. Int J Nanomedicine. 2023;18:185–205. We, the Editor and Publisher of the journal International Journal of Nanomedicine are retracting the published article.
Naseer F +6 more
doaj +2 more sources

