Thiolated-Polymer-Based Nanoparticles as an Avant-Garde Approach for Anticancer Therapies—Reviewing Thiomers from Chitosan and Hyaluronic Acid [PDF]
Pharmaceutics, 2021 Thiomers (or thiolated polymers) have broken through as avant-garde approaches in anticancer therapy. Their distinguished reactivity and properties, closely linked to their final applications, justify the extensive research conducted on their preparation
Roberto Grosso, M.-Violante de-Paz
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Thiomers: A Blessing to Evaluating Era of Pharmaceuticals [PDF]
International Journal of Polymer Science, 2015 Thiomers are the polymers modified for the mucoadhesive properties and other additive properties by incorporating thiol moieties in the backbone of the unmodified polymeric chain by substitution reactions or simple oxidation reactions.
Muhammad Hanif +2 more
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Improved Mucoadhesion, Permeation and In Vitro Anticancer Potential of Synthesized Thiolated Acacia and Karaya Gum Combination: A Systematic Study [PDF]
Molecules, 2022 Thiolation of polymers is one of the most appropriate approaches to impart higher mechanical strength and mucoadhesion. Thiol modification of gum karaya and gum acacia was carried out by esterification with 80% thioglycolic acid.
Neha Munot +6 more
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Augmentation of Antidiabetic Activity of Glibenclamide Microspheres Using S-Protected Okra Powered by QbD: Scintigraphy and In Vivo Studies [PDF]
Pharmaceuticals, 2022 Successful drug delivery by mucoadhesive systems depends on the polymer type, which usually gets adherent on hydration. The intended polymers must sustain the association with biomembranes and preserve or accommodate the drug for an extended time.
Waleed Y. Rizg +12 more
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Rapid and label-free Listeria monocytogenes detection based on stimuli-responsive alginate-platinum thiomer nanobrushes [PDF]
Scientific Reports, 2022 In this work, we demonstrate the development of a rapid and label-free electrochemical biosensor to detect Listeria monocytogenes using a novel stimulus–response thiomer nanobrush material.
Daniela A. Oliveira +2 more
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Pharmaceutics, 2023 Purpose: The aim of this research was to prepare adhesive nanoparticles for the topical application of Minoxidil (MXD). Methods: Thiolated β-CDs were prepared via conjugation of cysteamine with oxidized CDs.
Ammara Akhtar +7 more
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Thiolated Chitosan Conjugated Liposomes for Oral Delivery of Selenium Nanoparticles
Pharmaceutics, 2022 This study aimed to design a hybrid oral liposomal delivery system for selenium nanoparticles (Lip-SeNPs) to improve the bioavailability of selenium.
Atiđa Selmani +13 more
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Intraoral Drug Delivery: Highly Thiolated κ-Carrageenan as Mucoadhesive Excipient
Pharmaceutics, 2023 Aim: This study aims to design a novel thiolated κ-carrageenan (κ-CA-SH) and evaluate its potential as an excipient for the design of mucoadhesive drug delivery systems.
Gergely Kali +4 more
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British Journal of Pharmacy, 2023 This study focuses on the optimisation of pectin thiolation using L-cysteine and assesses the impact of the degree of esterification (DE), polymer to L-cysteine ratio, and concentrations of conjugating reagents on the total and free thiol content of both
Jack Phillip Brown +2 more
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Applied Sciences, 2021 During wound healing, the rapid re-establishment of a functional microcirculation in the wounded tissue is of utmost importance. We applied optical coherence tomography (OCT) angiography to evaluate vascular remodeling in an excisional wound model in the
Martin Pfister +9 more
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