Results 31 to 40 of about 103,347 (189)

Enhancing Osteoporosis Treatment through Targeted Nanoparticle Delivery of Risedronate: In Vivo Evaluation and Bioavailability Enhancement

open access: yesPharmaceutics, 2023
Risedronate-loaded mPEG-coated hydroxyapatite, thiolated chitosan-based (coated) and non-coated nanoparticles were tested for their potential effects in the treatment of osteoporosis.
Zoya Saifi   +9 more
doaj   +1 more source

Halloysites modified polyethylene glycol diacrylate/thiolated chitosan double network hydrogel combined with BMP-2 for rat skull regeneration

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2021
Hydrogel serve as bone tissue engineering have lately received great attention for their good biocompatibility and structures similar to natural extracellular matrices.
Qi-Bin Sun   +4 more
doaj   +1 more source

Fabrication of thiolated chitosan based biodegradable nanoparticles of ticagrelor and their pharmacokinetics

open access: yesPolymers and Polymer Composites, 2022
The current study was aimed to design a thiolated chitosan (TC) based mucoadhesive nanoparticle (NP) formulation for enhancing the oral bioavailability of an anti-coagulant, Ticagrelor (TG).
Nariman Shahid   +10 more
doaj   +1 more source

Mucoadhesive polymer films for tissue retraction in laparoscopic surgery : ex-vivo study on their mechanical properties [PDF]

open access: yes, 2014
This work was financially supported by the Engineering and Physical Sciences Research Council (EPSRC), UK, under Grant EP/H010033/1 and the Royal Society (GJF).Safe and effective manipulation of soft tissue during laparoscopic procedures can be achieved ...
Florence, Gordon John   +10 more
core   +1 more source

Thiolated Chitosans: A Multi-talented Class of Polymers for Various Applications [PDF]

open access: yesBiomacromolecules, 2020
Various properties of chitosan can be customized by thiolation for very specific needs in a wide range of application areas. Since the discovery of thiolated chitosans, many studies have proven their advantageous characteristics, such as adhesion to biological surfaces, adjustable cross-linking and swelling behavior, controllable drug release ...
Christoph Federer   +2 more
openaire   +2 more sources

Pharmacokinetic Investigation to Study the In Vivo Bioavailability of Thiolated Chitosan Based Repaglinide Buccal Tablets [PDF]

open access: yesPharmaceutical Sciences, 2020
Background: Repaglinide (REP) is an antihyperglycemic drug having low bioavailability due to its extensive first-pass metabolism. The present study aimed to develop and pharmacokinetic investigte the thiolated chitosan (TC) based buccal tablets of REP ...
Raja Navamanisubramanian   +2 more
doaj   +1 more source

Disulfide bond reconstruction: A novel approach for grafting of thiolated chitosan onto wool [PDF]

open access: yes, 2018
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Chitosan, a natural biopolymer, is used as a multifunctional agent for modification of wool either through ...
Zhang, Pan   +5 more
core   +1 more source

Enhancing drug delivery through chemical modification of chitosan: A review [PDF]

open access: yesPharmacia
Chitosan is a natural polysaccharide used in the pharmaceutical industry and medicine due to its hydrophilic, biocompatible, biodegradable, and non-toxic properties. However, it is insoluble in water, which limits its applications.
Daniel Argilashki, Yordanka Uzunova
doaj   +3 more sources

S-protected thiolated chitosan: Synthesis and in vitro characterization

open access: yesCarbohydrate Polymers, 2012
Purpose of the present study was the generation and evaluation of novel thiolated chitosans, so-named S-protected thiolated chitosans as mucosal drug delivery systems. Stability of all conjugates concerning swelling and disintegration behavior as well as drug release was examined.
Dünnhaupt, Sarah   +5 more
openaire   +2 more sources

Photo‐inactivation of bacteria in hospital effluent via thiolated iron‐doped nanoceria

open access: yesIET Nanobiotechnology, 2019
Hospital wastewater is a major contributor of disease‐causing microbes and the emergence of antibiotic resistant bacteria. In this study, thiolated iron‐doped nanoceria was synthesised and tested for killing of microbes from hospital effluent.
Sara Khan   +4 more
doaj   +1 more source

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