Results 161 to 170 of about 7,935 (218)
Disseminated Tuberculosis With Placental Involvement in a Crohn's Disease Patient Treated With Combination Therapy. [PDF]
Gastro Hep Advde Castro Borges N +5 more
europepmc +1 more source
Proteomics Approaches for Discovering Novel Protein Biomarkers in Inflammatory Bowel Disease-Related Cancer. [PDF]
BiomoleculesSaccon T, Bergamo M, Franchin C.
europepmc +1 more source
Clinical and Economic Impact of Expanded TPMT Testing to Prevent Thiopurine-Induced Myelosuppression in Australia: A Budget Impact Analysis. [PDF]
Clin Transl SciIanni BD +4 more
europepmc +1 more source
[Pharmacogenetic study of thiopurine S-methyltransferase (TPMT) and thiopurine toxicity].
Revista espanola de enfermedades digestivas, 2003 H, Corominas +3 more
openaire +1 more source
Pharmacogenetics of thiopurines [PDF]
Cancer Drug Resistance (Alhambra, Calif ), 2019 Polychemotherapeutic protocols for the treatment of pediatric acute lymphoblastic leukemia (ALL) always include thiopurines. Specific approaches vary in terms of drugs, dosages and combinations. Such therapeutic schemes, including risk-adapted intensity, have been extremely successful for children with ALL who have reached an outstanding 5-year ...
Raffaella Franca +2 more
exaly +5 more sources
Digestive and Liver Disease, 2021 International audienceThe role of thiopurines in therapeutic algorithms of Crohn's disease (CD) and Ulcerative colitis (UC) is being questioned. This work aimed to investigate current practice and future perspectives of Inflammatory Bowel Disease (IBD ...
Manuel Barreiro de Acosta +2 more
exaly +2 more sources
Thiopurines’ Metabolites and Drug Toxicity: A Meta-Analysis
Journal of Clinical Medicine, 2020 Many questions remain unanswered regarding therapeutic drug monitoring (TDM) utility with thiopurines. This study aims to establish a relationship between thiopurines’ metabolites and drug toxicity.
Maria Manuela Estevinho +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
British Journal of Hospital Medicine, 2013
Thiopurines are a class of immunosuppressant and antineoplastic drugs developed by Gertrude Elion and George Hitchings and patented in 1953 for use to treat leukaemia, then used to prevent transplant rejection (Marx, 2005).
Kl, de Wit, Be, White, D, Goldsmith
openaire +3 more sources
Thiopurines are a class of immunosuppressant and antineoplastic drugs developed by Gertrude Elion and George Hitchings and patented in 1953 for use to treat leukaemia, then used to prevent transplant rejection (Marx, 2005).
Kl, de Wit, Be, White, D, Goldsmith
openaire +3 more sources
Investigational New Drugs, 2005
The thiopurine drugs, 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) are commonly used cytotoxic agents. A derivative of 6-MP, azathioprine, is commonly used as an immunosuppressant. A prominent route for the metabolism of these agents is mediated by the enzyme thiopurine methyltransferase (TPMT).
Sally, Coulthard, Linda, Hogarth
openaire +2 more sources
The thiopurine drugs, 6-mercaptopurine (6-MP), 6-thioguanine (6-TG) are commonly used cytotoxic agents. A derivative of 6-MP, azathioprine, is commonly used as an immunosuppressant. A prominent route for the metabolism of these agents is mediated by the enzyme thiopurine methyltransferase (TPMT).
Sally, Coulthard, Linda, Hogarth
openaire +2 more sources