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Thiopurine pharmacogenetics: clinical and molecular studies of thiopurine methyltransferase.
Drug metabolism and disposition: the biological fate of chemicals, 2001Thiopurine drugs are used to treat patients with neoplasia and autoimmune disease as well as transplant recipients. These agents are metabolized, in part, by S-methylation catalyzed by thiopurine methyltransferase (TPMT). The discovery nearly two decades ago that levels of TPMT activity in human tissues are controlled by a common genetic polymorphism ...
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Intrauterine exposure to thiopurines
Reproductive Toxicology, 2012Jharap, B. +3 more
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Thiopurine biology and pharmacology
Trends in Pharmacological Sciences, 1997J, Aarbakke, G, Janka-Schaub, G B, Elion
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The use of thiopurines for the treatment of inflammatory bowel diseases in clinical practice
Digestive and Liver Disease, 2008Simone Saibeni +2 more
exaly

